FI47101B - - Google Patents

Info

Publication number
FI47101B
FI47101B FI257570A FI257570A FI47101B FI 47101 B FI47101 B FI 47101B FI 257570 A FI257570 A FI 257570A FI 257570 A FI257570 A FI 257570A FI 47101 B FI47101 B FI 47101B
Authority
FI
Finland
Application number
FI257570A
Other languages
Finnish (fi)
Other versions
FI47101C (en
Inventor
Gal George
Sletzinger Meyer
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of FI47101B publication Critical patent/FI47101B/fi
Publication of FI47101C publication Critical patent/FI47101C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/281-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/36Oxygen atoms in position 3, e.g. adrenochrome

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI257570A 1963-02-01 1970-09-21 Process for the preparation of therapeutically active alpha- (3-indolyl) -lower aliphatic acids. FI47101C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25564263A 1963-02-01 1963-02-01

Publications (2)

Publication Number Publication Date
FI47101B true FI47101B (en) 1973-05-31
FI47101C FI47101C (en) 1973-09-10

Family

ID=22969254

Family Applications (9)

Application Number Title Priority Date Filing Date
FI16964A FI46955C (en) 1963-02-01 1964-01-29 Process for the preparation of therapeutically active 1-p-chlorobenzoyl-2-lower alkyl-5-lower alkoxy-3-indolylacetic acid
FI257170A FI47098C (en) 1963-02-01 1970-09-21 Process for the preparation of 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetaldehyde having an anti-inflammatory, antipyretic and analgesic effect.
FI257370A FI47185C (en) 1963-02-01 1970-09-21 Process for the preparation of 1-p-chlorobenzoyl-2-methyl-5-methoxy-indole-3-ethanol with anti-inflammatory and antipyretic action.
FI257070A FI47097B (en) 1963-02-01 1970-09-21
FI257270A FI47099C (en) 1963-02-01 1970-09-21 A process for preparing 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetic acid having anti-inflammatory, antipyretic and analgesic activity.
FI257570A FI47101C (en) 1963-02-01 1970-09-21 Process for the preparation of therapeutically active alpha- (3-indolyl) -lower aliphatic acids.
FI702570A FI47097C (en) 1963-02-01 1970-09-21 Process for the preparation of therapeutically effective 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetic acid.
FI256870A FI47096C (en) 1963-02-01 1970-09-21 Process for the preparation of tert-butyl ester of therapeutically active alpha- (3-indolyl) lower aliphatic acids.
FI257470A FI47100C (en) 1963-02-01 1970-09-21 Process for the preparation of therapeutically active 1-p-chlorobenzoyl-2-lower-alkyl-5-lower-alkoxy-3-indolyl-acetic acid.

Family Applications Before (5)

Application Number Title Priority Date Filing Date
FI16964A FI46955C (en) 1963-02-01 1964-01-29 Process for the preparation of therapeutically active 1-p-chlorobenzoyl-2-lower alkyl-5-lower alkoxy-3-indolylacetic acid
FI257170A FI47098C (en) 1963-02-01 1970-09-21 Process for the preparation of 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetaldehyde having an anti-inflammatory, antipyretic and analgesic effect.
FI257370A FI47185C (en) 1963-02-01 1970-09-21 Process for the preparation of 1-p-chlorobenzoyl-2-methyl-5-methoxy-indole-3-ethanol with anti-inflammatory and antipyretic action.
FI257070A FI47097B (en) 1963-02-01 1970-09-21
FI257270A FI47099C (en) 1963-02-01 1970-09-21 A process for preparing 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetic acid having anti-inflammatory, antipyretic and analgesic activity.

Family Applications After (3)

Application Number Title Priority Date Filing Date
FI702570A FI47097C (en) 1963-02-01 1970-09-21 Process for the preparation of therapeutically effective 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetic acid.
FI256870A FI47096C (en) 1963-02-01 1970-09-21 Process for the preparation of tert-butyl ester of therapeutically active alpha- (3-indolyl) lower aliphatic acids.
FI257470A FI47100C (en) 1963-02-01 1970-09-21 Process for the preparation of therapeutically active 1-p-chlorobenzoyl-2-lower-alkyl-5-lower-alkoxy-3-indolyl-acetic acid.

Country Status (11)

Country Link
AT (1) AT277992B (en)
BE (1) BE643268A (en)
BR (1) BR6456479D0 (en)
CH (16) CH464203A (en)
DE (16) DE1695492A1 (en)
DK (11) DK109334C (en)
FI (9) FI46955C (en)
FR (1) FR1559559A (en)
GB (13) GB1050737A (en)
NL (1) NL6400813A (en)
SE (12) SE317975B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU163233B (en) * 1970-07-31 1973-07-28
ATE79741T1 (en) * 1988-06-21 1992-09-15 Rauter Vita Zahnfabrik DISPERSED CERAMIC COMPOUND.
GB9518994D0 (en) * 1995-09-16 1995-11-15 Agrevo Uk Ltd Fungicides

Also Published As

Publication number Publication date
CH466283A (en) 1968-12-15
DE1695486A1 (en) 1971-04-15
DK109514C (en) 1968-05-06
GB1050737A (en)
CH489495A (en) 1970-04-30
CH466286A (en) 1968-12-15
NL6400813A (en) 1964-08-03
GB1050738A (en)
DE1695489A1 (en) 1970-08-13
DK112313B (en) 1968-12-02
GB1050736A (en)
FI46955C (en) 1973-08-10
SE320367B (en) 1970-02-09
GB1050739A (en)
DK109562C (en) 1968-05-13
CH457436A (en) 1968-06-15
CH457434A (en) 1968-06-15
FI47099C (en) 1973-09-10
DE1695484A1 (en) 1971-04-15
FI47096C (en) 1973-09-10
BE643268A (en) 1964-07-31
FI47100B (en) 1973-05-31
DE1695493A1 (en) 1971-04-01
DE1695492A1 (en) 1971-04-01
GB1050740A (en)
DE1695491A1 (en) 1971-04-15
CH466288A (en) 1968-12-15
CH466285A (en) 1968-12-15
FI47100C (en) 1973-09-10
FI47098B (en) 1973-05-31
GB1050733A (en)
GB1050729A (en)
CH457435A (en) 1968-06-15
FI47097B (en) 1973-05-31
SE307133B (en) 1968-12-23
FI47097C (en) 1973-09-10
CH466287A (en) 1968-12-15
CH464202A (en) 1968-10-31
CH466290A (en) 1968-12-15
CH464203A (en) 1968-10-31
SE302463B (en) 1968-07-22
DK112238B (en) 1968-11-25
FI47101C (en) 1973-09-10
DE1770134A1 (en) 1971-09-30
FI47099B (en) 1973-05-31
CH466289A (en) 1968-12-15
SE302130B (en) 1968-07-08
CH557815A (en) 1975-01-15
CH466284A (en) 1968-12-15
SE302133B (en) 1968-07-08
SE307948B (en) 1969-01-27
SE304995B (en) 1968-10-14
DK112314B (en) 1968-12-02
DK112239B (en) 1968-11-25
DE1470059B1 (en) 1970-01-29
DK113501B (en) 1969-03-31
DE1695490A1 (en) 1971-04-15
DK112447B (en) 1968-12-16
DE1695487A1 (en) 1970-10-01
SE320666B (en) 1970-02-16
AT277992B (en) 1970-01-12
GB1050732A (en)
FI47098C (en) 1973-09-10
GB1050731A (en)
DE1770132A1 (en) 1971-09-30
DE1770802A1 (en) 1972-02-17
DK111751B (en) 1968-10-07
FI47185B (en) 1973-07-02
GB1050734A (en)
DK112446B (en) 1968-12-16
SE317975B (en) 1969-12-01
DE1770116A1 (en) 1971-10-14
DE1695488A1 (en) 1970-09-17
SE302132B (en) 1968-07-08
GB1050728A (en)
CH457437A (en) 1968-06-15
SE320069B (en) 1970-02-02
SE302131B (en) 1968-07-08
FI47185C (en) 1973-10-10
DE1695485A1 (en) 1971-04-15
FI47096B (en) 1973-05-31
FR1559559A (en) 1969-03-14
DE1793561A1 (en) 1972-01-20
GB1050730A (en)
DK109334C (en) 1968-04-16
GB1050735A (en)
BR6456479D0 (en) 1973-09-20
FI46955B (en) 1973-05-02

Similar Documents

Publication Publication Date Title
FI47098B (en)
AT260747B (en)
BE627012A (en)
BE642549A (en)
BE462764A (en)
BE465565A (en)
BE507458A (en)
BE533484A (en)
BE547422A (en)
BE571209A (en)
BE582314A (en)
BE603935A (en)
BE608372A (en)
BE612803A (en)
BE614220A (en)
BE616247A (en)
BE616830A (en)
BE616967A (en)
BE619061A (en)
BE620325A (en)
BE621232A (en)
BE621517A (en)
BE622160A (en)
BE623117A (en)
BE623162A (en)