FI47098C - Process for the preparation of 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetaldehyde having an anti-inflammatory, antipyretic and analgesic effect. - Google Patents
Process for the preparation of 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetaldehyde having an anti-inflammatory, antipyretic and analgesic effect.Info
- Publication number
- FI47098C FI47098C FI257170A FI257170A FI47098C FI 47098 C FI47098 C FI 47098C FI 257170 A FI257170 A FI 257170A FI 257170 A FI257170 A FI 257170A FI 47098 C FI47098 C FI 47098C
- Authority
- FI
- Finland
- Prior art keywords
- indolylacetaldehyde
- antipyretic
- chlorobenzoyl
- inflammatory
- methoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25564263A | 1963-02-01 | 1963-02-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI47098B FI47098B (en) | 1973-05-31 |
| FI47098C true FI47098C (en) | 1973-09-10 |
Family
ID=22969254
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI16964A FI46955C (en) | 1963-02-01 | 1964-01-29 | Process for the preparation of therapeutically active 1-p-chlorobenzoyl-2-lower alkyl-5-lower alkoxy-3-indolylacetic acid |
| FI702570A FI47097C (en) | 1963-02-01 | 1970-09-21 | Process for the preparation of therapeutically effective 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetic acid. |
| FI257570A FI47101C (en) | 1963-02-01 | 1970-09-21 | Process for the preparation of therapeutically active alpha- (3-indolyl) -lower aliphatic acids. |
| FI257070A FI47097B (en) | 1963-02-01 | 1970-09-21 | |
| FI257270A FI47099C (en) | 1963-02-01 | 1970-09-21 | A process for preparing 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetic acid having anti-inflammatory, antipyretic and analgesic activity. |
| FI257170A FI47098C (en) | 1963-02-01 | 1970-09-21 | Process for the preparation of 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetaldehyde having an anti-inflammatory, antipyretic and analgesic effect. |
| FI257370A FI47185C (en) | 1963-02-01 | 1970-09-21 | Process for the preparation of 1-p-chlorobenzoyl-2-methyl-5-methoxy-indole-3-ethanol with anti-inflammatory and antipyretic action. |
| FI257470A FI47100C (en) | 1963-02-01 | 1970-09-21 | Process for the preparation of therapeutically active 1-p-chlorobenzoyl-2-lower-alkyl-5-lower-alkoxy-3-indolyl-acetic acid. |
| FI256870A FI47096C (en) | 1963-02-01 | 1970-09-21 | Process for the preparation of tert-butyl ester of therapeutically active alpha- (3-indolyl) lower aliphatic acids. |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI16964A FI46955C (en) | 1963-02-01 | 1964-01-29 | Process for the preparation of therapeutically active 1-p-chlorobenzoyl-2-lower alkyl-5-lower alkoxy-3-indolylacetic acid |
| FI702570A FI47097C (en) | 1963-02-01 | 1970-09-21 | Process for the preparation of therapeutically effective 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetic acid. |
| FI257570A FI47101C (en) | 1963-02-01 | 1970-09-21 | Process for the preparation of therapeutically active alpha- (3-indolyl) -lower aliphatic acids. |
| FI257070A FI47097B (en) | 1963-02-01 | 1970-09-21 | |
| FI257270A FI47099C (en) | 1963-02-01 | 1970-09-21 | A process for preparing 1-p-chlorobenzoyl-2-methyl-5-methoxy-3-indolylacetic acid having anti-inflammatory, antipyretic and analgesic activity. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI257370A FI47185C (en) | 1963-02-01 | 1970-09-21 | Process for the preparation of 1-p-chlorobenzoyl-2-methyl-5-methoxy-indole-3-ethanol with anti-inflammatory and antipyretic action. |
| FI257470A FI47100C (en) | 1963-02-01 | 1970-09-21 | Process for the preparation of therapeutically active 1-p-chlorobenzoyl-2-lower-alkyl-5-lower-alkoxy-3-indolyl-acetic acid. |
| FI256870A FI47096C (en) | 1963-02-01 | 1970-09-21 | Process for the preparation of tert-butyl ester of therapeutically active alpha- (3-indolyl) lower aliphatic acids. |
Country Status (11)
| Country | Link |
|---|---|
| AT (1) | AT277992B (en) |
| BE (1) | BE643268A (en) |
| BR (1) | BR6456479D0 (en) |
| CH (16) | CH457435A (en) |
| DE (16) | DE1695492A1 (en) |
| DK (11) | DK109334C (en) |
| FI (9) | FI46955C (en) |
| FR (1) | FR1559559A (en) |
| GB (13) | GB1050738A (en) |
| NL (1) | NL6400813A (en) |
| SE (12) | SE302463B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU163233B (en) * | 1970-07-31 | 1973-07-28 | ||
| DE58902127D1 (en) * | 1988-06-21 | 1992-10-01 | Rauter Vita Zahnfabrik | DISPERSED CERAMICS. |
| GB9518994D0 (en) * | 1995-09-16 | 1995-11-15 | Agrevo Uk Ltd | Fungicides |
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0
- GB GB1050728D patent/GB1050728A/en active Active
- GB GB1050736D patent/GB1050736A/en active Active
- GB GB1050729D patent/GB1050729A/en active Active
- GB GB1050733D patent/GB1050733A/en active Active
- GB GB1050740D patent/GB1050740A/en active Active
- GB GB1050735D patent/GB1050735A/en active Active
- GB GB1050734D patent/GB1050734A/en active Active
- GB GB1050732D patent/GB1050732A/en active Active
- GB GB1050737D patent/GB1050737A/en active Active
- GB GB1050739D patent/GB1050739A/en active Active
- GB GB1050731D patent/GB1050731A/en active Active
- GB GB1050730D patent/GB1050730A/en active Active
- GB GB1050738D patent/GB1050738A/en active Active
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1964
- 1964-01-14 DE DE19641695492 patent/DE1695492A1/en active Pending
- 1964-01-24 DE DE19641770116 patent/DE1770116A1/en active Pending
- 1964-01-24 DE DE19641695488 patent/DE1695488A1/en active Pending
- 1964-01-24 DE DE19641770132 patent/DE1770132A1/en active Pending
- 1964-01-24 DE DE19641695490 patent/DE1695490A1/en active Pending
- 1964-01-24 DE DE19641695484 patent/DE1695484A1/en active Pending
- 1964-01-24 DE DE19641470059D patent/DE1470059B1/en active Pending
- 1964-01-24 DE DE19641695487 patent/DE1695487A1/en active Pending
- 1964-01-24 DE DE19641695485 patent/DE1695485A1/en active Pending
- 1964-01-24 DE DE19641695491 patent/DE1695491A1/en active Pending
- 1964-01-24 DE DE19641695486 patent/DE1695486A1/en active Pending
- 1964-01-24 DE DE19641793561 patent/DE1793561A1/en active Pending
- 1964-01-24 DE DE19641695489 patent/DE1695489A1/en active Pending
- 1964-01-24 DE DE19641770802 patent/DE1770802A1/en active Pending
- 1964-01-24 DE DE19641695493 patent/DE1695493A1/en active Pending
- 1964-01-24 DE DE19641770134 patent/DE1770134A1/en active Pending
- 1964-01-28 AT AT01821/67A patent/AT277992B/en not_active IP Right Cessation
- 1964-01-28 BR BR15647964A patent/BR6456479D0/en unknown
- 1964-01-29 FI FI16964A patent/FI46955C/en active
- 1964-01-31 CH CH236068A patent/CH457435A/en unknown
- 1964-01-31 CH CH236268A patent/CH557815A/en not_active IP Right Cessation
- 1964-01-31 CH CH1674768A patent/CH466290A/en unknown
- 1964-01-31 CH CH444166A patent/CH466285A/en unknown
- 1964-01-31 CH CH236168A patent/CH464202A/en unknown
- 1964-01-31 CH CH490268A patent/CH466286A/en unknown
- 1964-01-31 NL NL6400813A patent/NL6400813A/xx unknown
- 1964-01-31 CH CH1674468A patent/CH466288A/en unknown
- 1964-01-31 FR FR1559559D patent/FR1559559A/fr not_active Expired
- 1964-01-31 SE SE89267A patent/SE302463B/xx unknown
- 1964-01-31 SE SE88967A patent/SE317975B/xx unknown
- 1964-01-31 CH CH236368A patent/CH457436A/en unknown
- 1964-01-31 BE BE643268D patent/BE643268A/xx unknown
- 1964-01-31 DK DK598765A patent/DK109334C/en active
- 1964-01-31 CH CH236568A patent/CH464203A/en unknown
- 1964-01-31 CH CH235868A patent/CH457434A/en unknown
- 1964-01-31 CH CH490368A patent/CH466287A/en unknown
- 1964-01-31 CH CH1674568A patent/CH466289A/en unknown
- 1964-01-31 SE SE123764A patent/SE307948B/xx unknown
- 1964-01-31 DK DK598265A patent/DK109562C/en active
- 1964-01-31 DK DK598565A patent/DK109514C/en active
- 1964-01-31 CH CH419468A patent/CH466284A/en unknown
- 1964-01-31 CH CH236668A patent/CH457437A/en unknown
- 1964-01-31 DK DK48964A patent/DK112238B/en unknown
- 1964-01-31 CH CH236468A patent/CH466283A/en unknown
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1965
- 1965-11-22 DK DK598965A patent/DK112314B/en unknown
- 1965-11-22 DK DK598665A patent/DK112239B/en unknown
- 1965-11-22 DK DK598365A patent/DK113501B/en unknown
- 1965-11-22 DK DK598465A patent/DK111751B/en unknown
- 1965-11-22 DK DK598865A patent/DK112313B/en unknown
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1966
- 1966-02-23 DK DK93366A patent/DK112447B/en unknown
- 1966-02-23 DK DK93266A patent/DK112446B/en unknown
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1967
- 1967-01-20 SE SE89367A patent/SE302133B/en unknown
- 1967-01-20 SE SE895/67A patent/SE320069B/xx unknown
- 1967-01-20 SE SE896/67A patent/SE320666B/xx unknown
- 1967-01-20 SE SE894/67A patent/SE320367B/xx unknown
- 1967-01-20 SE SE890/67A patent/SE307133B/xx unknown
- 1967-01-20 SE SE891/67A patent/SE304995B/xx unknown
- 1967-01-20 SE SE88667A patent/SE302130B/en unknown
- 1967-01-20 SE SE88867A patent/SE302132B/en unknown
- 1967-01-31 SE SE88767A patent/SE302131B/xx unknown
- 1967-02-23 CH CH115364A patent/CH489495A/en not_active IP Right Cessation
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1970
- 1970-09-21 FI FI702570A patent/FI47097C/en active
- 1970-09-21 FI FI257570A patent/FI47101C/en active
- 1970-09-21 FI FI257070A patent/FI47097B/fi active
- 1970-09-21 FI FI257270A patent/FI47099C/en active
- 1970-09-21 FI FI257170A patent/FI47098C/en active
- 1970-09-21 FI FI257370A patent/FI47185C/en active
- 1970-09-21 FI FI257470A patent/FI47100C/en active
- 1970-09-21 FI FI256870A patent/FI47096C/en active
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