FI3671200T3 - Ce-western-sovelluksia vasta-aineen kehittämiseksi - Google Patents
Ce-western-sovelluksia vasta-aineen kehittämiseksi Download PDFInfo
- Publication number
- FI3671200T3 FI3671200T3 FIEP19218272.3T FI19218272T FI3671200T3 FI 3671200 T3 FI3671200 T3 FI 3671200T3 FI 19218272 T FI19218272 T FI 19218272T FI 3671200 T3 FI3671200 T3 FI 3671200T3
- Authority
- FI
- Finland
- Prior art keywords
- antibody
- primary antibodies
- sample
- antibodies
- detecting
- Prior art date
Links
- 238000011161 development Methods 0.000 title claims 2
- 238000000034 method Methods 0.000 claims 51
- 235000004252 protein component Nutrition 0.000 claims 14
- 239000011159 matrix material Substances 0.000 claims 10
- 235000018102 proteins Nutrition 0.000 claims 9
- 102000004169 proteins and genes Human genes 0.000 claims 9
- 108090000623 proteins and genes Proteins 0.000 claims 9
- 238000000926 separation method Methods 0.000 claims 9
- 239000000356 contaminant Substances 0.000 claims 7
- 238000001514 detection method Methods 0.000 claims 7
- 238000011835 investigation Methods 0.000 claims 5
- 239000000959 ampholyte mixture Substances 0.000 claims 3
- 238000005251 capillar electrophoresis Methods 0.000 claims 3
- 230000003100 immobilizing effect Effects 0.000 claims 3
- 238000012216 screening Methods 0.000 claims 2
- 101001074414 Homo sapiens Putative phospholipase B-like 2 Proteins 0.000 claims 1
- 102100036164 Putative phospholipase B-like 2 Human genes 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 238000012360 testing method Methods 0.000 claims 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
- G01N27/44726—Arrangements for investigating the separated zones, e.g. localising zones by optical means using specific dyes, markers or binding molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44743—Introducing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44795—Isoelectric focusing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862781790P | 2018-12-19 | 2018-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3671200T3 true FI3671200T3 (fi) | 2023-08-28 |
Family
ID=69410996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP19218272.3T FI3671200T3 (fi) | 2018-12-19 | 2019-12-19 | Ce-western-sovelluksia vasta-aineen kehittämiseksi |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11782023B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP4253950A3 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2020101545A (cg-RX-API-DMAC7.html) |
| CA (1) | CA3065460A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK3671200T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2955171T3 (cg-RX-API-DMAC7.html) |
| FI (1) | FI3671200T3 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE062818T2 (cg-RX-API-DMAC7.html) |
| PL (1) | PL3671200T3 (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102799360B1 (ko) * | 2019-05-21 | 2025-04-25 | 리제너론 파아마슈티컬스, 인크. | 숙주 세포 단백질 동정 및 정량화 방법 |
| WO2023177836A1 (en) * | 2022-03-18 | 2023-09-21 | Regeneron Pharmaceuticals, Inc. | Methods and systems for analyzing polypeptide variants |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5002582A (en) | 1982-09-29 | 1991-03-26 | Bio-Metric Systems, Inc. | Preparation of polymeric surfaces via covalently attaching polymers |
| US6087188A (en) | 1992-11-13 | 2000-07-11 | Alk A/S | Two-site immunoassay for an antibody with chemiluminescent label and biotin bound ligand |
| JPH09507571A (ja) | 1993-12-23 | 1997-07-29 | トロピックス・インコーポレーテッド | 化学発光エネルギー移動検定 |
| DE69605712T2 (de) | 1995-03-31 | 2000-04-27 | Laboratory Of Molecular Biophotonics, Hamakita | Anwendung von isoelektrischen Punkt Markern bei der isoelektrischen Fokussierung mit Fluoreszenzdetektierung |
| US6165800A (en) | 1997-05-30 | 2000-12-26 | Bayer Corporation | Chemiluminescent energy transfer conjugates and their uses as labels in binding assays |
| US6126870A (en) | 1997-09-12 | 2000-10-03 | Lumigen, Inc. | Chemiluminescent labeling compounds |
| US6254634B1 (en) | 1998-06-10 | 2001-07-03 | Surmodics, Inc. | Coating compositions |
| WO2000009626A1 (en) | 1998-08-14 | 2000-02-24 | Dainichiseika Color & Chemicals Mfg. Co., Ltd. | Chemiluminescent reagents and chemiluminescence analysis methods with the use of the same |
| ATE556149T1 (de) | 1999-02-23 | 2012-05-15 | Caliper Life Sciences Inc | Manipulation von mikropartikeln in mikrofluidischen systemen |
| JP2001249079A (ja) | 1999-12-28 | 2001-09-14 | Fujirebio Inc | 発光量調節剤を用いた化学発光測定方法及び酵素免疫測定方法 |
| WO2006014680A1 (en) * | 2004-07-19 | 2006-02-09 | Cell Biosciences, Inc. | Methods and devices for analyte detection |
| WO2007035864A2 (en) | 2005-09-20 | 2007-03-29 | Cell Biosciences, Inc. | Electrophoresis standards, methods and kits |
| US20090023156A1 (en) * | 2007-07-20 | 2009-01-22 | Voss Karl O | Methods and reagents for quantifying analytes |
| KR20120027055A (ko) * | 2009-06-26 | 2012-03-20 | 리제네론 파라마큐티칼스 인코포레이티드 | 천연 면역글로불린 포맷을 가지는 용이하게 분리된 이중특이성 항체 |
| US9766206B2 (en) * | 2013-09-27 | 2017-09-19 | ProteinSimple | Apparatus, systems, and methods for capillary electrophoresis |
| AU2016261854B2 (en) * | 2015-05-12 | 2022-05-26 | Regeneron Pharmaceuticals, Inc. | Multimeric protein purity determination |
-
2019
- 2019-12-17 US US16/716,734 patent/US11782023B2/en active Active
- 2019-12-18 CA CA3065460A patent/CA3065460A1/en active Pending
- 2019-12-19 EP EP23180401.4A patent/EP4253950A3/en not_active Withdrawn
- 2019-12-19 ES ES19218272T patent/ES2955171T3/es active Active
- 2019-12-19 PL PL19218272.3T patent/PL3671200T3/pl unknown
- 2019-12-19 EP EP19218272.3A patent/EP3671200B1/en active Active
- 2019-12-19 JP JP2019228754A patent/JP2020101545A/ja not_active Ceased
- 2019-12-19 DK DK19218272.3T patent/DK3671200T3/da active
- 2019-12-19 HU HUE19218272A patent/HUE062818T2/hu unknown
- 2019-12-19 FI FIEP19218272.3T patent/FI3671200T3/fi active
-
2023
- 2023-06-23 US US18/213,390 patent/US20230417701A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3065460A1 (en) | 2020-06-19 |
| EP3671200B1 (en) | 2023-06-21 |
| DK3671200T3 (da) | 2023-08-21 |
| ES2955171T3 (es) | 2023-11-29 |
| EP4253950A3 (en) | 2024-01-17 |
| EP4253950A2 (en) | 2023-10-04 |
| US20230417701A1 (en) | 2023-12-28 |
| US20200200707A1 (en) | 2020-06-25 |
| PL3671200T3 (pl) | 2023-10-09 |
| US11782023B2 (en) | 2023-10-10 |
| JP2020101545A (ja) | 2020-07-02 |
| EP3671200A1 (en) | 2020-06-24 |
| HUE062818T2 (hu) | 2023-12-28 |
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