FI3314123T3 - Järjestelmiä, laitteita ja menetelmiä solujen lajitteluun ja virtaussytometriaan - Google Patents

Järjestelmiä, laitteita ja menetelmiä solujen lajitteluun ja virtaussytometriaan Download PDF

Info

Publication number
FI3314123T3
FI3314123T3 FIEP16815271.8T FI16815271T FI3314123T3 FI 3314123 T3 FI3314123 T3 FI 3314123T3 FI 16815271 T FI16815271 T FI 16815271T FI 3314123 T3 FI3314123 T3 FI 3314123T3
Authority
FI
Finland
Prior art keywords
liquid
sample
fluid
channel
sheath
Prior art date
Application number
FIEP16815271.8T
Other languages
English (en)
Finnish (fi)
Inventor
Jose M Morachis
Sung Hwan Cho
Zhe Mei
Phillip Poonka
Constance Ardila
Gerardo Narez
William Alaynick
Original Assignee
Nanocellect Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanocellect Biomedical Inc filed Critical Nanocellect Biomedical Inc
Application granted granted Critical
Publication of FI3314123T3 publication Critical patent/FI3314123T3/fi

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/04—Pumps having electric drive
    • F04B43/043—Micropumps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B3/00—Devices comprising flexible or deformable elements, e.g. comprising elastic tongues or membranes
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B11/00—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation
    • F04B11/0008—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation using accumulators
    • F04B11/0016—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation using accumulators with a fluid spring
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/0009—Special features
    • F04B43/0081—Special features systems, control, safety measures
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/1253—Machines, pumps, or pumping installations having flexible working members having peristaltic action by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing
    • F04B43/1292—Pumps specially adapted for several tubular flexible members
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/06—Control using electricity
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/08—Regulating by delivery pressure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
    • G01N15/1427—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement with the synchronisation of components, a time gate for operation of components, or suppression of particle coincidences
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457—Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B2205/00—Fluid parameters
    • F04B2205/50—Presence of foreign matter in the fluid
    • F04B2205/503—Presence of foreign matter in the fluid of gas in a liquid flow, e.g. gas bubbles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409—Handling samples, e.g. injecting samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Computer Hardware Design (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Reciprocating Pumps (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Fuel Cell (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
FIEP16815271.8T 2015-06-23 2016-06-23 Järjestelmiä, laitteita ja menetelmiä solujen lajitteluun ja virtaussytometriaan FI3314123T3 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562183640P 2015-06-23 2015-06-23
PCT/US2016/038937 WO2016210077A1 (en) 2015-06-23 2016-06-23 Systems, apparatuses, and methods for cell sorting and flow cytometry

Publications (1)

Publication Number Publication Date
FI3314123T3 true FI3314123T3 (fi) 2024-05-02

Family

ID=57586330

Family Applications (1)

Application Number Title Priority Date Filing Date
FIEP16815271.8T FI3314123T3 (fi) 2015-06-23 2016-06-23 Järjestelmiä, laitteita ja menetelmiä solujen lajitteluun ja virtaussytometriaan

Country Status (8)

Country Link
US (1) US20180163713A1 (enExample)
EP (2) EP4374964A3 (enExample)
JP (2) JP2018523114A (enExample)
CN (1) CN107923382B (enExample)
DK (1) DK3314123T3 (enExample)
ES (1) ES2977951T3 (enExample)
FI (1) FI3314123T3 (enExample)
WO (1) WO2016210077A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105008895B (zh) 2012-10-15 2019-02-15 纳诺赛莱克特生物医药股份有限公司 颗粒分选的系统、设备和方法
US11982611B2 (en) 2017-03-20 2024-05-14 Nanocellect Biomedical, Inc. Systems, apparatuses, and methods for cell sorting and flow cytometry
US20200011782A1 (en) * 2017-03-31 2020-01-09 Sony Corporation Flow channel unit and microparticle analysis device
US11525767B2 (en) 2017-05-24 2022-12-13 Sony Corporation Optimizing method of suction condition of microparticle and microparticle fractionating device
CN110031386B (zh) * 2019-05-16 2023-12-26 重庆博奥新景医学科技有限公司 一种流式细胞仪液路系统及其检测方法
CN114829626A (zh) 2019-10-10 2022-07-29 1859公司 用于微流体筛选的方法和系统
CN114556085A (zh) * 2019-11-05 2022-05-27 索尼集团公司 微粒分选微芯片的灌注方法、微粒分选方法、微粒分选装置和程序
CN113418898B (zh) * 2021-06-18 2022-10-28 贵州医科大学 一种pifo平台的由微流控芯片和荧光传感器组成的集成装置
JP7679254B2 (ja) * 2021-08-05 2025-05-19 株式会社エンプラス 液体取扱装置および液体取扱システム
CN117054177A (zh) * 2022-05-07 2023-11-14 贝克曼库尔特生物科技（苏州）有限公司 流体系统、样本处理仪和在样本处理仪中输送流体的方法
US20240091774A1 (en) * 2022-09-15 2024-03-21 Halcyon Biomedical, Incorporated Passive pressure wave dampener systems
EP4339459A1 (en) * 2022-09-15 2024-03-20 Halcyon Biomedical, Incorporated Passive pressure wave dampener systems

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5828091A (ja) * 1981-08-13 1983-02-18 株式会社石川製作所 脈動防止装置
US7214298B2 (en) * 1997-09-23 2007-05-08 California Institute Of Technology Microfabricated cell sorter
WO1999061888A2 (en) * 1998-05-22 1999-12-02 California Institute Of Technology Microfabricated cell sorter
EP1322936A2 (en) * 2000-10-03 2003-07-02 California Institute Of Technology Microfluidic devices and methods of use
US20080177131A1 (en) * 2000-10-06 2008-07-24 Dancu Michael B Systems and methods of preparing a hybrid coronary bypass vascular graft intended for implantation into a mammal
US6976590B2 (en) * 2002-06-24 2005-12-20 Cytonome, Inc. Method and apparatus for sorting particles
US7157274B2 (en) * 2002-06-24 2007-01-02 Cytonome, Inc. Method and apparatus for sorting particles
EP1663460B1 (en) * 2003-09-04 2015-07-08 Premium Genetics (UK) Limited Multiple laminar flow-based particle and cellular separation with laser steering
JP5138223B2 (ja) * 2003-10-30 2013-02-06 サイトノーム エスティー リミテッド ライアビリティー カンパニー 流体力学的多層シースフロー構造
US9260693B2 (en) * 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
CN101099082B (zh) * 2004-12-03 2013-03-27 塞通诺米/St有限责任公司 用于粒子处理的整体式盒
FR2880880B1 (fr) * 2005-01-18 2008-06-20 Bertin Technologies Soc Par Ac Remplissage d'un microcanal d'un composant d'un microsysteme fluidique
US8303894B2 (en) * 2005-10-13 2012-11-06 Accuri Cytometers, Inc. Detection and fluidic system of a flow cytometer
US8017402B2 (en) * 2006-03-08 2011-09-13 Accuri Cytometers, Inc. Fluidic system for a flow cytometer
JP2007176161A (ja) * 2005-11-30 2007-07-12 Brother Ind Ltd 吐出タイミング決定方法及び液滴吐出方法
US7328722B2 (en) * 2005-12-07 2008-02-12 Accuri Cytometers, Inc. Pulsation attenuator for a fluidic system
US7857005B2 (en) * 2005-12-07 2010-12-28 Accuri Cytometers, Inc. Pulsation attenuator for a fluidic system
US8715573B2 (en) * 2006-10-13 2014-05-06 Accuri Cytometers, Inc. Fluidic system for a flow cytometer with temporal processing
WO2009022994A1 (en) * 2007-08-13 2009-02-19 Agency For Science, Technology And Research Microfluidic separation system
US9134221B2 (en) 2009-03-10 2015-09-15 The Regents Of The University Of California Fluidic flow cytometry devices and particle sensing based on signal-encoding
EP2462347A1 (en) * 2009-08-03 2012-06-13 Koninklijke Philips Electronics N.V. Low restriction resonator with adjustable frequency characteristics for use in compressor nebulizer systems
EP2295096B1 (en) * 2009-09-11 2016-02-10 F. Hoffmann-La Roche AG Micro-fluidic chambers for use in liquid medicament delivery systems
JP5381741B2 (ja) * 2010-01-21 2014-01-08 ソニー株式会社 光学的測定装置及び光学的測定方法
US8366667B2 (en) 2010-02-11 2013-02-05 Baxter International Inc. Flow pulsatility dampening devices
JP2012192641A (ja) * 2011-03-17 2012-10-11 Brother Industries Ltd 液滴噴射装置
CN116165124A (zh) 2012-05-30 2023-05-26 艾瑞斯国际有限公司 流式细胞仪
JP5872403B2 (ja) * 2012-07-20 2016-03-01 株式会社日立ハイテクノロジーズ 生体物質分析用フローセルの製造方法に用いる治具
US10379029B2 (en) * 2012-09-18 2019-08-13 Cytonome/St, Llc Flow cell
CN103970220B (zh) * 2013-01-30 2018-11-06 鸿富锦精密电子(天津)有限公司 扩展卡固定装置
JP6089817B2 (ja) * 2013-03-12 2017-03-08 株式会社リコー 液体吐出ヘッド、画像形成装置
US10371622B2 (en) * 2013-03-14 2019-08-06 Inguran, Llc Device for high throughput sperm sorting
KR20160075568A (ko) * 2013-10-16 2016-06-29 클리어브릿지 바이오메딕스 피티이 엘티디 세포 검출 및 분리를 위한 마이크로유체 분류기
US9963693B2 (en) * 2013-10-21 2018-05-08 Biomet Biologics, Llc Cell washing device using a wave
US20150166956A1 (en) * 2013-12-16 2015-06-18 General Electric Company Devices for separation of particulates, associated methods and systems

Also Published As

Publication number Publication date
EP3314123B1 (en) 2024-04-03
EP3314123A1 (en) 2018-05-02
JP2021192045A (ja) 2021-12-16
CN107923382A (zh) 2018-04-17
CN107923382B (zh) 2019-11-08
EP3314123A4 (en) 2018-11-14
ES2977951T3 (es) 2024-09-03
EP4374964A3 (en) 2024-06-19
EP4374964A2 (en) 2024-05-29
US20180163713A1 (en) 2018-06-14
JP2018523114A (ja) 2018-08-16
JP7397833B2 (ja) 2023-12-13
DK3314123T3 (da) 2024-04-29
WO2016210077A1 (en) 2016-12-29

Similar Documents

Publication Publication Date Title
FI3314123T3 (fi) Järjestelmiä, laitteita ja menetelmiä solujen lajitteluun ja virtaussytometriaan
JP2017525345A5 (enExample)
JP2018523114A5 (enExample)
WO2016073415A3 (en) Microscale plasma separator
GB2556582A (en) Microfluidic devices and methods of use thereof
EP4335471A3 (en) Apparatus for monitoring, regulating, or controlling fluid flow
MX2018007314A (es) Sistema generador de aerosol que comprende entrada de aire variable.
EP2949471A3 (en) Liquid storage unit, liquid discharge apparatus using the same, and method of removing bubbles from liquid storage unit
EP4566715A3 (en) Systems and methods for handling microfluidic droplets
MX2019015772A (es) Dispositivo de transferencia de presion y el sistema y uso asociados, para bombear grandes volumenes de fluidos con particulas a altas presiones.
WO2014011543A3 (en) Perfusion apparatus with reduced pressure fluctuations, and bubble trap
WO2015044454A3 (en) A microfluidic device, use and methods
MX2017014546A (es) Aparatos y metodos para eliminacion de gas intravenoso.
MX2020007588A (es) Dispositivo microfluidico con microcamaras ventiladas.
WO2016128843A8 (en) Disposable cartridge for sample fluid analysis
ATE555309T1 (de) Dämpfer zur reduzierung von druckfluktuationen in einem hydraulischen system
MX380098B (es) Aparato de filtración.
RU2011146136A (ru) Безгазовая камера для текучих сред
GB2580538A8 (en) Gas chromatograph-ion mobility spectrometry combined equipment
EP2722274A3 (en) Flow control actuator with an adjustable frequency
EP3912708A3 (en) Systems and methods for dissolving a gas into a liquid
MX2018005003A (es) Dispensador.
WO2019067319A3 (en) Microfluidic technique for detection of multi-contact miscibility
EP2848768A3 (en) Oil pump
EP3196923A3 (en) Improving ion transfer tube flow and pumping system load