MX2020007588A - Dispositivo microfluidico con microcamaras ventiladas. - Google Patents

Dispositivo microfluidico con microcamaras ventiladas.

Info

Publication number
MX2020007588A
MX2020007588A MX2020007588A MX2020007588A MX2020007588A MX 2020007588 A MX2020007588 A MX 2020007588A MX 2020007588 A MX2020007588 A MX 2020007588A MX 2020007588 A MX2020007588 A MX 2020007588A MX 2020007588 A MX2020007588 A MX 2020007588A
Authority
MX
Mexico
Prior art keywords
reaction chamber
chamber
microchamber
fluid sample
microfluidic device
Prior art date
Application number
MX2020007588A
Other languages
English (en)
Inventor
Kabir James Yamana
Sean Yamana-Hayes
Original Assignee
Qiagen Sciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qiagen Sciences Llc filed Critical Qiagen Sciences Llc
Publication of MX2020007588A publication Critical patent/MX2020007588A/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Un dispositivo microfluídico con un circuito microfluídico que incluye un conjunto de microcámaras acopladas fluidamente. Cada microcámara incluye una cámara de reacción y una cámara de ventilación asociada. El circuito microfluídico se puede disponer de modo que una muestra de fluido introducida en el dispositivo microfluídico fluya al interior de la cámara de reacción y aire u otro gas presente en la cámara de reacción se evacúe de la microcámara a través de la cámara de ventilación. La microcámara se puede configurar para permitir solamente el flujo de aire al interior de la cámara de ventilación desde la cámara de reacción hasta que el aire haya sido desplazado de la cámara de reacción por la muestra de fluido y/o se haya recibido un volumen predefinido de la muestra de fluido en la cámara de reacción. La microcámara se puede configurar además para liberar la muestra de fluido para que fluya posteriormente de la cámara de reacción al interior de la cámara de ventilación.
MX2020007588A 2018-01-17 2018-12-20 Dispositivo microfluidico con microcamaras ventiladas. MX2020007588A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/873,722 US11154864B2 (en) 2018-01-17 2018-01-17 Microfluidic device with vented microchambers
PCT/US2018/066706 WO2019143440A1 (en) 2018-01-17 2018-12-20 Microfluidic device with vented microchambers

Publications (1)

Publication Number Publication Date
MX2020007588A true MX2020007588A (es) 2020-09-03

Family

ID=65024085

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020007588A MX2020007588A (es) 2018-01-17 2018-12-20 Dispositivo microfluidico con microcamaras ventiladas.

Country Status (13)

Country Link
US (3) US11154864B2 (es)
EP (1) EP3740314B1 (es)
JP (1) JP7366907B2 (es)
KR (1) KR102696831B1 (es)
CN (1) CN111601661B (es)
AU (1) AU2018403222B2 (es)
CA (1) CA3088509A1 (es)
ES (1) ES2973486T3 (es)
MX (1) MX2020007588A (es)
PL (1) PL3740314T3 (es)
RU (1) RU2020126690A (es)
SG (1) SG11202006413RA (es)
WO (1) WO2019143440A1 (es)

Families Citing this family (5)

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US11154864B2 (en) * 2018-01-17 2021-10-26 Qiagen Sciences, Llc Microfluidic device with vented microchambers
LU102655B1 (en) 2021-03-11 2022-09-12 STRATEC CONSUMABLES GmbH Structures for supporting the filling of wells in microfluidic devices
WO2023221023A1 (zh) * 2022-05-19 2023-11-23 京东方科技集团股份有限公司 基因检测基板、基因检测芯片及基因检测样本的制备方法
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EP4435717A1 (en) 2023-03-24 2024-09-25 QIAGEN GmbH Method for providing an analysis of partition image data

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Also Published As

Publication number Publication date
JP7366907B2 (ja) 2023-10-23
EP3740314A1 (en) 2020-11-25
CA3088509A1 (en) 2019-07-25
US20210379593A1 (en) 2021-12-09
CN111601661B (zh) 2023-03-14
US20190217298A1 (en) 2019-07-18
AU2018403222A1 (en) 2020-07-09
US11819851B2 (en) 2023-11-21
EP3740314C0 (en) 2024-02-28
EP3740314B1 (en) 2024-02-28
JP2021511492A (ja) 2021-05-06
WO2019143440A1 (en) 2019-07-25
SG11202006413RA (en) 2020-08-28
AU2018403222B2 (en) 2024-06-20
KR20200110652A (ko) 2020-09-24
RU2020126690A (ru) 2022-02-17
US20240042444A1 (en) 2024-02-08
ES2973486T3 (es) 2024-06-20
PL3740314T3 (pl) 2024-07-22
US11154864B2 (en) 2021-10-26
BR112020013457A2 (pt) 2020-12-01
KR102696831B1 (ko) 2024-08-21
CN111601661A (zh) 2020-08-28

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