FI20095466A0 - Adenoviraalisia vektoreita ja niihin liittyviä menetelmiä ja käyttöjä - Google Patents

Adenoviraalisia vektoreita ja niihin liittyviä menetelmiä ja käyttöjä

Info

Publication number
FI20095466A0
FI20095466A0 FI20095466A FI20095466A FI20095466A0 FI 20095466 A0 FI20095466 A0 FI 20095466A0 FI 20095466 A FI20095466 A FI 20095466A FI 20095466 A FI20095466 A FI 20095466A FI 20095466 A0 FI20095466 A0 FI 20095466A0
Authority
FI
Finland
Prior art keywords
methods
adenoviral vectors
uses related
adenoviral
vectors
Prior art date
Application number
FI20095466A
Other languages
English (en)
Swedish (sv)
Other versions
FI121508B (fi
Inventor
Akseli Hemminki
Anna Kanerva
Vincenzo Cerullo
Sari Pesonen
Original Assignee
Anna Kanerva
Vincenzo Cerullo
Sari Pesonen
Akseli Hemminki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anna Kanerva, Vincenzo Cerullo, Sari Pesonen, Akseli Hemminki filed Critical Anna Kanerva
Publication of FI20095466A0 publication Critical patent/FI20095466A0/fi
Priority to FI20095466A priority Critical patent/FI121508B/fi
Priority to SI200931586A priority patent/SI2379586T1/sl
Priority to PT97960165T priority patent/PT2379586T/pt
Priority to BRPI0924123A priority patent/BRPI0924123B8/pt
Priority to AU2009332883A priority patent/AU2009332883B2/en
Priority to JP2011542856A priority patent/JP2012513209A/ja
Priority to KR1020117016272A priority patent/KR101761094B1/ko
Priority to CA2748180A priority patent/CA2748180C/en
Priority to US12/643,140 priority patent/US9345787B2/en
Priority to RU2011130511/10A priority patent/RU2520823C2/ru
Priority to SG2011046109A priority patent/SG173432A1/en
Priority to PL09796016T priority patent/PL2379586T3/pl
Priority to EP09796016.5A priority patent/EP2379586B1/en
Priority to LTEP09796016.5T priority patent/LT2379586T/lt
Priority to HUE09796016A priority patent/HUE031689T2/en
Priority to ES09796016.5T priority patent/ES2612889T3/es
Priority to PCT/FI2009/051025 priority patent/WO2010072900A1/en
Priority to DK09796016.5T priority patent/DK2379586T3/en
Priority to CN200980151762.9A priority patent/CN102264760B/zh
Application granted granted Critical
Publication of FI121508B publication Critical patent/FI121508B/fi
Priority to ZA2011/04224A priority patent/ZA201104224B/en
Priority to US14/538,707 priority patent/US20150202324A1/en
Priority to JP2015156226A priority patent/JP6280084B2/ja
Priority to US15/075,962 priority patent/US20160208287A1/en
Priority to CY20171100126T priority patent/CY1120039T1/el
Priority to HRP20170165TT priority patent/HRP20170165T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • C12N15/861Adenoviral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/761Adenovirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2810/00Vectors comprising a targeting moiety
    • C12N2810/50Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/60Vectors comprising as targeting moiety peptide derived from defined protein from viruses
    • C12N2810/6009Vectors comprising as targeting moiety peptide derived from defined protein from viruses dsDNA viruses
    • C12N2810/6018Adenoviridae

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI20095466A 2008-12-22 2009-04-27 Adenovirusvektoreita ja niihin liittyviä menetelmiä ja käyttöjä FI121508B (fi)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FI20095466A FI121508B (fi) 2008-12-22 2009-04-27 Adenovirusvektoreita ja niihin liittyviä menetelmiä ja käyttöjä
EP09796016.5A EP2379586B1 (en) 2008-12-22 2009-12-21 Oncolytic adenoviral vectors and methods and uses related thereto
HUE09796016A HUE031689T2 (en) 2008-12-22 2009-12-21 Oncolytic adenoviral vectors and related procedures and applications
BRPI0924123A BRPI0924123B8 (pt) 2008-12-22 2009-12-21 vetores adenovirais oncolíticos, usos dos mesmos, composição farmacêutica e método para produzir gmcsf em uma célula in vitro
AU2009332883A AU2009332883B2 (en) 2008-12-22 2009-12-21 Oncolytic adenoviral vectors and methods and uses related thereto
JP2011542856A JP2012513209A (ja) 2008-12-22 2009-12-21 腫瘍溶解アデノウイルスベクター並びに前記に関連する方法および使用
KR1020117016272A KR101761094B1 (ko) 2008-12-22 2009-12-21 종양용해성 아데노바이러스 벡터 및 이와 관련된 방법 및 용도
CA2748180A CA2748180C (en) 2008-12-22 2009-12-21 Oncolytic adenoviral vectors and methods and uses related thereto
US12/643,140 US9345787B2 (en) 2008-12-22 2009-12-21 Adenoviral vectors and methods and uses related thereto
RU2011130511/10A RU2520823C2 (ru) 2008-12-22 2009-12-21 Аденовирусные векторы и способы и применения, связанные с ними
SG2011046109A SG173432A1 (en) 2008-12-22 2009-12-21 Oncolytic adenoviral vectors and methods and uses related thereto
PL09796016T PL2379586T3 (pl) 2008-12-22 2009-12-21 Onkolityczne wektory adenowirusowe i związane z nimi sposoby i zastosowania
SI200931586A SI2379586T1 (sl) 2008-12-22 2009-12-21 Onkolitični adenovirusni vektorji in z njimi povezani postopki in uporabe
LTEP09796016.5T LT2379586T (lt) 2008-12-22 2009-12-21 Auglio audinius ardantys adenovirusiniai vektoriai ir su jais susiję būdai ir panaudojimas
PT97960165T PT2379586T (pt) 2008-12-22 2009-12-21 Vectores adenovirais oncolíticos e respectivos métodos e utilizações
ES09796016.5T ES2612889T3 (es) 2008-12-22 2009-12-21 Vectores adenovíricos oncolíticos y procedimientos y utilizaciones relacionados con los mismos
PCT/FI2009/051025 WO2010072900A1 (en) 2008-12-22 2009-12-21 Oncolytic adenoviral vectors and methods and uses related thereto
DK09796016.5T DK2379586T3 (en) 2008-12-22 2009-12-21 Oncolytic adenoviral vectors and methods and applications associated therewith
CN200980151762.9A CN102264760B (zh) 2008-12-22 2009-12-21 溶瘤性腺病毒载体及与其相关的方法和用途
ZA2011/04224A ZA201104224B (en) 2008-12-22 2011-06-07 Oncolytic adenoviral vectors and methods and uses related thereto
US14/538,707 US20150202324A1 (en) 2008-12-22 2014-11-11 Adenoviral vectors and methods and uses related thereto
JP2015156226A JP6280084B2 (ja) 2008-12-22 2015-08-06 腫瘍溶解アデノウイルスベクター並びに前記に関連する方法および使用
US15/075,962 US20160208287A1 (en) 2008-12-22 2016-03-21 Adenoviral vectors and methods and uses related thereto
CY20171100126T CY1120039T1 (el) 2008-12-22 2017-01-27 Ογκολυτικοι αδενοϊικοι φορεις και μεθοδοι και χρησεις οι οποιες σχετιζονται με αυτους
HRP20170165TT HRP20170165T1 (hr) 2008-12-22 2017-02-01 Onkolitički adenovirusni vektori i metode i uporabe u vezi s time

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FI20080671 2008-12-22
FI20080671A FI20080671A0 (fi) 2008-12-22 2008-12-22 Onkolyyttiset virukset
FI20095466A FI121508B (fi) 2008-12-22 2009-04-27 Adenovirusvektoreita ja niihin liittyviä menetelmiä ja käyttöjä
FI20095466 2009-04-27

Publications (2)

Publication Number Publication Date
FI20095466A0 true FI20095466A0 (fi) 2009-04-27
FI121508B FI121508B (fi) 2010-12-15

Family

ID=40240530

Family Applications (2)

Application Number Title Priority Date Filing Date
FI20080671A FI20080671A0 (fi) 2008-12-22 2008-12-22 Onkolyyttiset virukset
FI20095466A FI121508B (fi) 2008-12-22 2009-04-27 Adenovirusvektoreita ja niihin liittyviä menetelmiä ja käyttöjä

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI20080671A FI20080671A0 (fi) 2008-12-22 2008-12-22 Onkolyyttiset virukset

Country Status (1)

Country Link
FI (2) FI20080671A0 (fi)

Also Published As

Publication number Publication date
FI121508B (fi) 2010-12-15
FI20080671A0 (fi) 2008-12-22

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