FI20060428L - Pintamodifioidut aerosolihiukkaset, menetelmä ja laite niiden tuottamiseksi sekä jauheet ja dispersiot jotka sisältävät kyseisiä hiukkasia - Google Patents

Pintamodifioidut aerosolihiukkaset, menetelmä ja laite niiden tuottamiseksi sekä jauheet ja dispersiot jotka sisältävät kyseisiä hiukkasia Download PDF

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Publication number
FI20060428L
FI20060428L FI20060428A FI20060428A FI20060428L FI 20060428 L FI20060428 L FI 20060428L FI 20060428 A FI20060428 A FI 20060428A FI 20060428 A FI20060428 A FI 20060428A FI 20060428 L FI20060428 L FI 20060428L
Authority
FI
Finland
Prior art keywords
particles
powders
production
dispersions containing
modified aerosol
Prior art date
Application number
FI20060428A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI20060428A0 (fi
Inventor
Esko Kauppinen
Janne Raula
David Brown
Anna Laehde
Original Assignee
Esko Kauppinen
Janne Raula
David Brown
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esko Kauppinen, Janne Raula, David Brown filed Critical Esko Kauppinen
Priority to FI20060428A priority Critical patent/FI20060428L/fi
Publication of FI20060428A0 publication Critical patent/FI20060428A0/fi
Priority to CN200780053165A priority patent/CN101702885A/zh
Priority to EP07730620.7A priority patent/EP2164622B1/de
Priority to JP2010509853A priority patent/JP2010528094A/ja
Priority to BRPI0721714A priority patent/BRPI0721714A2/pt
Priority to US12/602,228 priority patent/US8349295B2/en
Priority to PCT/FI2007/000151 priority patent/WO2007125159A1/en
Priority to CA2688288A priority patent/CA2688288C/en
Publication of FI20060428L publication Critical patent/FI20060428L/fi

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0095Preparation of aerosols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
FI20060428A 2006-05-03 2006-05-03 Pintamodifioidut aerosolihiukkaset, menetelmä ja laite niiden tuottamiseksi sekä jauheet ja dispersiot jotka sisältävät kyseisiä hiukkasia FI20060428L (fi)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FI20060428A FI20060428L (fi) 2006-05-03 2006-05-03 Pintamodifioidut aerosolihiukkaset, menetelmä ja laite niiden tuottamiseksi sekä jauheet ja dispersiot jotka sisältävät kyseisiä hiukkasia
CN200780053165A CN101702885A (zh) 2006-05-03 2007-05-31 表面改性的气溶胶粒子、用于其生产的方法和设备以及包含所述粒子的粉末和分散体
EP07730620.7A EP2164622B1 (de) 2006-05-03 2007-05-31 Oberflächenmodifizierte aerosolteilchen, verfahren zu ihrer herstellung und pulver und dispersionen, die die teilchen enthalten
JP2010509853A JP2010528094A (ja) 2006-05-03 2007-05-31 表面改質されたエアロゾル粒子、その製造のための方法および装置ならびにこの粒子を含む粉末および分散液
BRPI0721714A BRPI0721714A2 (pt) 2006-05-03 2007-05-31 partícula de aerossol de superfície modificada, método e dispositivo para produção das mesmas e pós e dispersões contendo as ditas partículas
US12/602,228 US8349295B2 (en) 2006-05-03 2007-05-31 Surface modified aerosol particles, a method and apparatus for production thereof and powders and dispersions containing said particles
PCT/FI2007/000151 WO2007125159A1 (en) 2006-05-03 2007-05-31 Surface modified aerosol particles, a method and apparatus for production thereof and powders and dispersions containing said particles
CA2688288A CA2688288C (en) 2006-05-03 2007-05-31 Surface modified aerosol particles, a method and apparatus for production thereof and powders and dispersions containing said particles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20060428A FI20060428L (fi) 2006-05-03 2006-05-03 Pintamodifioidut aerosolihiukkaset, menetelmä ja laite niiden tuottamiseksi sekä jauheet ja dispersiot jotka sisältävät kyseisiä hiukkasia

Publications (2)

Publication Number Publication Date
FI20060428A0 FI20060428A0 (fi) 2006-05-03
FI20060428L true FI20060428L (fi) 2007-11-04

Family

ID=36539875

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20060428A FI20060428L (fi) 2006-05-03 2006-05-03 Pintamodifioidut aerosolihiukkaset, menetelmä ja laite niiden tuottamiseksi sekä jauheet ja dispersiot jotka sisältävät kyseisiä hiukkasia

Country Status (8)

Country Link
US (1) US8349295B2 (de)
EP (1) EP2164622B1 (de)
JP (1) JP2010528094A (de)
CN (1) CN101702885A (de)
BR (1) BRPI0721714A2 (de)
CA (1) CA2688288C (de)
FI (1) FI20060428L (de)
WO (1) WO2007125159A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7906453B2 (en) * 2008-01-04 2011-03-15 Cabot Corporation Processes for controlling catalyst particle morphology
WO2009142852A2 (en) * 2008-05-22 2009-11-26 3M Innovative Properties Company Process for manufacturing flowable powder drug compositions
CN104690295B (zh) * 2013-12-05 2017-06-30 南通建陵纳米科技有限公司 制备单分散超细颗粒的方法
EP3157675A1 (de) * 2014-06-09 2017-04-26 Canatu Oy Katalysatorpartikel und verfahren zur herstellung davon
CN105664807B (zh) * 2014-11-19 2019-10-29 中国辐射防护研究院 一种凝聚式单分散气溶胶发生装置
US9585835B1 (en) * 2015-09-16 2017-03-07 Sansa Corporation (Barbados) Inc. Inhalable nicotine formulations and methods of making and using the same
KR101827508B1 (ko) * 2016-05-19 2018-02-12 한국생산기술연구원 고온부식 방지 첨가제 제공장치
US20190133940A1 (en) * 2016-06-30 2019-05-09 Philip Morris Products S.A. Nicotine particles and compositions
UA126853C2 (uk) 2016-06-30 2023-02-15 Філіп Морріс Продактс С.А. Нікотиновмісні частинки
US20190202750A1 (en) * 2016-07-01 2019-07-04 Washington University Synthesis of nanocomposites and their use in enhancing plant nutrition
WO2018202818A1 (en) * 2017-05-04 2018-11-08 Nanologica Ab A process for manufacturing porous silica particles loaded with at least one bioactive compound adapted for lung, nasal, sublingual and/or pharyngeal delivery
EP3645092B1 (de) * 2017-06-30 2024-04-03 Avectas Limited Elektrospray-katheter
WO2022034029A1 (en) * 2020-08-11 2022-02-17 Merck Patent Gmbh Method for the collection of substances comprised in an environment for analytical purposes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990002546A1 (en) * 1988-09-09 1990-03-22 The Ronald T. Dodge Company Pharmaceuticals microencapsulated by vapor deposited polymers and method
JP3506854B2 (ja) * 1996-03-07 2004-03-15 シャープ株式会社 粒子表面改質方法およびその装置
US6051257A (en) * 1997-02-24 2000-04-18 Superior Micropowders, Llc Powder batch of pharmaceutically-active particles and methods for making same
JPH11169704A (ja) 1997-12-12 1999-06-29 Sharp Corp 粒子改質方法および粒子改質装置
JP3942732B2 (ja) * 1998-06-01 2007-07-11 シャープ株式会社 インク、カラーフィルタ、カラー表示装置およびこれらの製造方法
US7521068B2 (en) * 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
AU2918501A (en) * 1999-10-26 2001-05-08 Southern Illinois University Method for nanoparticle detection
FI20002215A0 (fi) * 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
FR2825271B1 (fr) 2001-05-31 2003-08-08 Oreal Composition en aerosol comprenant des particules de silicate et des polymeres

Also Published As

Publication number Publication date
EP2164622B1 (de) 2017-09-20
WO2007125159A1 (en) 2007-11-08
EP2164622A4 (de) 2013-10-23
FI20060428A0 (fi) 2006-05-03
CA2688288A1 (en) 2007-11-08
US20100239507A1 (en) 2010-09-23
BRPI0721714A2 (pt) 2016-10-11
CA2688288C (en) 2016-08-30
US8349295B2 (en) 2013-01-08
EP2164622A1 (de) 2010-03-24
JP2010528094A (ja) 2010-08-19
CN101702885A (zh) 2010-05-05

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