FI118511B - Pienten partikkelien muodostuminen - Google Patents
Pienten partikkelien muodostuminen Download PDFInfo
- Publication number
- FI118511B FI118511B FI971947A FI971947A FI118511B FI 118511 B FI118511 B FI 118511B FI 971947 A FI971947 A FI 971947A FI 971947 A FI971947 A FI 971947A FI 118511 B FI118511 B FI 118511B
- Authority
- FI
- Finland
- Prior art keywords
- polymer
- att
- solvent
- kännetecknat
- och
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/10—Complex coacervation, i.e. interaction of oppositely charged particles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Surgical Instruments (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heat Sensitive Colour Forming Recording (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Confectionery (AREA)
- Soft Magnetic Materials (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9403846 | 1994-11-09 | ||
SE9403846A SE9403846D0 (sv) | 1994-11-09 | 1994-11-09 | Small particle formation |
SE9501302 | 1995-11-03 | ||
PCT/SE1995/001302 WO1996014833A1 (en) | 1994-11-09 | 1995-11-03 | Small particle formation |
Publications (3)
Publication Number | Publication Date |
---|---|
FI971947A0 FI971947A0 (fi) | 1997-05-07 |
FI971947A FI971947A (fi) | 1997-05-07 |
FI118511B true FI118511B (fi) | 2007-12-14 |
Family
ID=20395907
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI971947A FI118511B (fi) | 1994-11-09 | 1997-05-07 | Pienten partikkelien muodostuminen |
Country Status (27)
Country | Link |
---|---|
US (1) | US5780062A (no) |
EP (1) | EP0788350B1 (no) |
JP (1) | JP4098827B2 (no) |
KR (1) | KR970706799A (no) |
CN (1) | CN1165478A (no) |
AT (1) | ATE213625T1 (no) |
AU (1) | AU700644B2 (no) |
BR (1) | BR9509720A (no) |
CA (1) | CA2203512A1 (no) |
CZ (1) | CZ129597A3 (no) |
DE (1) | DE69525639T2 (no) |
DK (1) | DK0788350T3 (no) |
EE (1) | EE9700214A (no) |
ES (1) | ES2173204T3 (no) |
FI (1) | FI118511B (no) |
HU (1) | HUT77629A (no) |
IL (1) | IL115878A0 (no) |
IS (1) | IS4467A (no) |
NO (1) | NO971986D0 (no) |
NZ (1) | NZ295497A (no) |
PL (1) | PL320425A1 (no) |
PT (1) | PT788350E (no) |
SE (1) | SE9403846D0 (no) |
SK (1) | SK55997A3 (no) |
TR (1) | TR199501400A2 (no) |
WO (1) | WO1996014833A1 (no) |
ZA (1) | ZA959386B (no) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE1009856A5 (fr) * | 1995-07-14 | 1997-10-07 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule. |
US6143211A (en) * | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
US7029700B2 (en) * | 2000-01-14 | 2006-04-18 | Brown University Research Foundation | Micronized freeze-dried particles |
AU2001231000A1 (en) * | 2000-01-19 | 2001-07-31 | Pharmaceutical Discovery Corporation | Dry powder formulations of antihistamine for nasal administration |
US9700866B2 (en) | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
US6869617B2 (en) * | 2000-12-22 | 2005-03-22 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
US20050048126A1 (en) | 2000-12-22 | 2005-03-03 | Barrett Rabinow | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
ATE319432T1 (de) * | 2000-12-22 | 2006-03-15 | Baxter Int | Verfahren zur herstellung von submikropartikel- suspensionen pharmazeutischer substanzen |
US6623761B2 (en) | 2000-12-22 | 2003-09-23 | Hassan Emadeldin M. | Method of making nanoparticles of substantially water insoluble materials |
US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
US6951656B2 (en) * | 2000-12-22 | 2005-10-04 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
US20040022862A1 (en) * | 2000-12-22 | 2004-02-05 | Kipp James E. | Method for preparing small particles |
US6977085B2 (en) * | 2000-12-22 | 2005-12-20 | Baxter International Inc. | Method for preparing submicron suspensions with polymorph control |
US7193084B2 (en) * | 2000-12-22 | 2007-03-20 | Baxter International Inc. | Polymorphic form of itraconazole |
US20030096013A1 (en) * | 2000-12-22 | 2003-05-22 | Jane Werling | Preparation of submicron sized particles with polymorph control |
US6884436B2 (en) * | 2000-12-22 | 2005-04-26 | Baxter International Inc. | Method for preparing submicron particle suspensions |
US20040256749A1 (en) * | 2000-12-22 | 2004-12-23 | Mahesh Chaubal | Process for production of essentially solvent-free small particles |
DE10117049A1 (de) * | 2001-04-05 | 2002-10-17 | Novartis Ag | Zusammensetzung |
EP1401399A2 (en) * | 2001-06-22 | 2004-03-31 | Pfizer Products Inc. | Pharmaceutical compositions containing polymer and drug assemblies |
BR0211705A (pt) * | 2001-08-06 | 2004-09-28 | Astrazeneca Ab | Processo para a preparação de uma dispersão estável de partìculas sólidas em um meio aquoso, dispersão estável aquosa, partìcula sólida, composição farmacêutica, método para a inibição do amadurecimento de ostwald em uma dispersão de partìculas sólidas substancialmente insolúveis em água em um meio aquoso, e, uso de um inibidor |
US6746635B2 (en) * | 2001-08-08 | 2004-06-08 | Brown University Research Foundation | Methods for micronization of hydrophobic drugs |
JP2005504090A (ja) | 2001-09-26 | 2005-02-10 | バクスター・インターナショナル・インコーポレイテッド | 分散体および溶媒相または液相の除去によるサブミクロンサイズ−ナノ粒子の調製 |
US20060003012A9 (en) * | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
US7112340B2 (en) * | 2001-10-19 | 2006-09-26 | Baxter International Inc. | Compositions of and method for preparing stable particles in a frozen aqueous matrix |
GB0216700D0 (en) * | 2002-07-18 | 2002-08-28 | Astrazeneca Ab | Process |
US20040028747A1 (en) * | 2002-08-06 | 2004-02-12 | Tucker Christopher J. | Crystalline drug particles prepared using a controlled precipitation process |
GB0230087D0 (en) * | 2002-12-24 | 2003-01-29 | Astrazeneca Ab | Therapeutic agents |
GB0230088D0 (en) * | 2002-12-24 | 2003-01-29 | Astrazeneca Ab | Therapeutic agents |
GB0302673D0 (en) * | 2003-02-06 | 2003-03-12 | Astrazeneca Ab | Pharmaceutical formulations |
GB0302672D0 (en) * | 2003-02-06 | 2003-03-12 | Astrazeneca Ab | Pharmaceutical formulations |
GB0302671D0 (en) * | 2003-02-06 | 2003-03-12 | Astrazeneca Ab | Pharmaceutical formulations |
US7511079B2 (en) * | 2003-03-24 | 2009-03-31 | Baxter International Inc. | Methods and apparatuses for the comminution and stabilization of small particles |
BRPI0410767A (pt) * | 2003-05-19 | 2006-07-04 | Baxter Int | formulações farmacêuticas de partìcula pequena de agentes antiataque e antidemência e agentes imunossupressores |
GB0314057D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
EP1641779A1 (en) * | 2003-06-18 | 2006-04-05 | AstraZeneca AB | 2-substitued 5, 6-diaryl-pyrazine derivatives as cb1 modulator. |
GB0314261D0 (en) * | 2003-06-19 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
US8986736B2 (en) * | 2003-06-24 | 2015-03-24 | Baxter International Inc. | Method for delivering particulate drugs to tissues |
EP1663158A2 (en) * | 2003-06-24 | 2006-06-07 | Baxter International Inc. | Specific delivery of drugs to the brain |
AU2004275764B2 (en) | 2003-09-22 | 2010-01-14 | Baxter Healthcare S.A. | High-pressure sterilization to terminally sterilize pharmaceutical preparations and medical products |
WO2005032511A2 (en) * | 2003-09-30 | 2005-04-14 | Spherics, Inc. | Nanoparticulate therapeutic biologically active agents |
DE10351087A1 (de) * | 2003-10-31 | 2005-05-25 | Bayer Technology Services Gmbh | Feste Wirkstoff-Formulierung |
EP1713443A2 (en) * | 2004-01-29 | 2006-10-25 | Baxter International Inc. | Nanosuspensions of anti-retroviral agents for increased central nervous system delivery |
EP1711163A2 (en) * | 2004-02-05 | 2006-10-18 | Baxter International Inc. | Dispersions prepared by use of self-stabilizing agents |
RU2006144851A (ru) * | 2004-06-15 | 2008-06-20 | Бакстер Интернэшнл Инк. (Us) | Применение терапевтических средств ex-vivo в виде твердых микрочастиц |
WO2006034147A2 (en) * | 2004-09-16 | 2006-03-30 | Abraxis Bioscience, Inc. | Compositions and methods for the preparation and administration of poorly water soluble drugs |
WO2008135828A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
WO2008135855A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer |
CA2723470C (en) * | 2007-05-07 | 2013-12-03 | Hale Biopharma Ventures, Llc | Nasal administration of benzodiazepines |
US8530463B2 (en) * | 2007-05-07 | 2013-09-10 | Hale Biopharma Ventures Llc | Multimodal particulate formulations |
US8426467B2 (en) | 2007-05-22 | 2013-04-23 | Baxter International Inc. | Colored esmolol concentrate |
US8722736B2 (en) | 2007-05-22 | 2014-05-13 | Baxter International Inc. | Multi-dose concentrate esmolol with benzyl alcohol |
WO2008149230A2 (en) | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate |
US8974827B2 (en) | 2007-06-04 | 2015-03-10 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
US8101274B2 (en) * | 2007-06-11 | 2012-01-24 | Spedden Richard H | Solid state membranes with surface-embedded glycosylated amphiphilic molecules and micelles formed therefrom |
GB0714223D0 (en) * | 2007-07-20 | 2007-08-29 | Fujifilm Mfg Europe Bv | Preparation of fine particles |
US9233078B2 (en) | 2007-12-06 | 2016-01-12 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer |
EP2231169B1 (en) | 2007-12-06 | 2016-05-04 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
RU2496482C2 (ru) | 2008-03-05 | 2013-10-27 | Бакстер Интернэшнл Инк. | Композиции и способы для доставки лекарственных средств |
US20090258865A1 (en) * | 2008-03-28 | 2009-10-15 | Hale Biopharma Ventures, Llc | Administration of benzodiazepine compositions |
CN101278921B (zh) * | 2008-06-03 | 2010-06-09 | 海南百那医药发展有限公司 | 盐酸托烷司琼微囊及其注射剂生产方法 |
US20100151037A1 (en) * | 2008-08-07 | 2010-06-17 | Yivan Jiang | Method for the preparation of nanoparticles containing a poorly water-soluble pharmaceutically active compound |
CN102176882A (zh) | 2008-08-07 | 2011-09-07 | 生物活性外科公司 | 医疗器械和植入物的干细胞捕获和固定涂层 |
US10952965B2 (en) * | 2009-05-15 | 2021-03-23 | Baxter International Inc. | Compositions and methods for drug delivery |
CN102784103A (zh) * | 2011-05-16 | 2012-11-21 | 中国科学院上海药物研究所 | 一种通过混合胶束技术制备的普罗布考纳米混悬液及其制备方法 |
WO2012170866A1 (en) * | 2011-06-10 | 2012-12-13 | Norac Pharma | Benzoyl peroxide microparticle process |
CN107737100A (zh) | 2011-06-14 | 2018-02-27 | 哈尔生物药投资有限责任公司 | 苯二氮卓组合物的投与 |
WO2015071841A1 (en) | 2013-11-12 | 2015-05-21 | Druggability Technologies Holdings Limited | Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them |
US20180155290A1 (en) * | 2015-05-08 | 2018-06-07 | Davuluri Ramamohan Rao | Improved Process for the Preparation of Aripiprazole with Reduced Particle Size |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3013839A1 (de) * | 1979-04-13 | 1980-10-30 | Freunt Ind Co Ltd | Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung |
CA1282405C (en) * | 1984-05-21 | 1991-04-02 | Michael R. Violante | Method for making uniformly sized particles from water-insoluble organic compounds |
US4826689A (en) * | 1984-05-21 | 1989-05-02 | University Of Rochester | Method for making uniformly sized particles from water-insoluble organic compounds |
US4606940A (en) * | 1984-12-21 | 1986-08-19 | The Ohio State University Research Foundation | Small particle formation and encapsulation |
JPH0249720A (ja) * | 1988-05-18 | 1990-02-20 | Mitsubishi Kasei Corp | 難溶性薬剤組成物 |
SE464743B (sv) * | 1989-06-21 | 1991-06-10 | Ytkemiska Inst | Foerfarande foer framstaellning av laekemedelspartiklar |
IT1243390B (it) * | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
-
1994
- 1994-11-09 SE SE9403846A patent/SE9403846D0/xx unknown
-
1995
- 1995-11-03 HU HU9800181A patent/HUT77629A/hu unknown
- 1995-11-03 KR KR1019970703072A patent/KR970706799A/ko not_active Application Discontinuation
- 1995-11-03 CA CA002203512A patent/CA2203512A1/en not_active Abandoned
- 1995-11-03 ES ES95938091T patent/ES2173204T3/es not_active Expired - Lifetime
- 1995-11-03 CN CN95196084A patent/CN1165478A/zh active Pending
- 1995-11-03 PT PT95938091T patent/PT788350E/pt unknown
- 1995-11-03 SK SK559-97A patent/SK55997A3/sk unknown
- 1995-11-03 AT AT95938091T patent/ATE213625T1/de not_active IP Right Cessation
- 1995-11-03 JP JP51597096A patent/JP4098827B2/ja not_active Expired - Fee Related
- 1995-11-03 EE EE9700214A patent/EE9700214A/xx unknown
- 1995-11-03 US US08/553,460 patent/US5780062A/en not_active Expired - Lifetime
- 1995-11-03 CZ CZ971295A patent/CZ129597A3/cs unknown
- 1995-11-03 PL PL95320425A patent/PL320425A1/xx unknown
- 1995-11-03 NZ NZ295497A patent/NZ295497A/en unknown
- 1995-11-03 DE DE69525639T patent/DE69525639T2/de not_active Expired - Lifetime
- 1995-11-03 WO PCT/SE1995/001302 patent/WO1996014833A1/en active IP Right Grant
- 1995-11-03 BR BR9509720A patent/BR9509720A/pt unknown
- 1995-11-03 AU AU38851/95A patent/AU700644B2/en not_active Ceased
- 1995-11-03 EP EP95938091A patent/EP0788350B1/en not_active Expired - Lifetime
- 1995-11-03 DK DK95938091T patent/DK0788350T3/da active
- 1995-11-06 ZA ZA959386A patent/ZA959386B/xx unknown
- 1995-11-06 IL IL11587895A patent/IL115878A0/xx unknown
- 1995-11-09 TR TR95/01400A patent/TR199501400A2/xx unknown
-
1997
- 1997-04-21 IS IS4467A patent/IS4467A/is unknown
- 1997-04-29 NO NO971986A patent/NO971986D0/no unknown
- 1997-05-07 FI FI971947A patent/FI118511B/fi not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CN1165478A (zh) | 1997-11-19 |
IL115878A0 (en) | 1996-01-31 |
AU700644B2 (en) | 1999-01-14 |
EP0788350B1 (en) | 2002-02-27 |
SE9403846D0 (sv) | 1994-11-09 |
JP4098827B2 (ja) | 2008-06-11 |
KR970706799A (ko) | 1997-12-01 |
ATE213625T1 (de) | 2002-03-15 |
CZ129597A3 (en) | 1997-12-17 |
US5780062A (en) | 1998-07-14 |
PT788350E (pt) | 2002-07-31 |
IS4467A (is) | 1997-04-21 |
DE69525639D1 (de) | 2002-04-04 |
FI971947A0 (fi) | 1997-05-07 |
NZ295497A (en) | 1998-05-27 |
WO1996014833A1 (en) | 1996-05-23 |
CA2203512A1 (en) | 1996-05-23 |
DK0788350T3 (da) | 2002-04-29 |
ES2173204T3 (es) | 2002-10-16 |
TR199501400A2 (tr) | 1996-06-21 |
PL320425A1 (en) | 1997-09-29 |
FI971947A (fi) | 1997-05-07 |
BR9509720A (pt) | 1997-10-21 |
NO971986L (no) | 1997-04-29 |
NO971986D0 (no) | 1997-04-29 |
HUT77629A (hu) | 1998-06-29 |
EP0788350A1 (en) | 1997-08-13 |
EE9700214A (et) | 1998-04-15 |
JPH10508840A (ja) | 1998-09-02 |
ZA959386B (en) | 1996-05-09 |
SK55997A3 (en) | 1998-01-14 |
AU3885195A (en) | 1996-06-06 |
DE69525639T2 (de) | 2002-08-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI118511B (fi) | Pienten partikkelien muodostuminen | |
Qin et al. | Supra-amphiphilic aggregates formed by p-sulfonatocalix [4] arenes and the antipsychotic drug chlorpromazine | |
Anal et al. | Preparation and characterization of nanoparticles formed by chitosan–caseinate interactions | |
Wang et al. | Stability of nanosuspensions in drug delivery | |
Nesamony et al. | Calcium alginate nanoparticles synthesized through a novel interfacial cross-linking method as a potential protein drug delivery system | |
Riley et al. | Colloidal stability and drug incorporation aspects of micellar-like PLA–PEG nanoparticles | |
EP0309527B1 (en) | Process for preparing a powder of water-insoluble polymer which can be redispersed in a liquid phase and process for preparing a dispersion of the powdered polymer | |
CN107410829B (zh) | 一种提高多糖/蛋白复合物乳化稳定性的方法 | |
JP2003521508A (ja) | リポソーム | |
HUT73808A (en) | Injectable liposomatic pharmaceutical compositions | |
Kroes-Nijboer et al. | Stability of aqueous food grade fibrillar systems against pH change | |
KR20180025318A (ko) | 친유성 화합물 전달용 나노캡슐 및 그 제조 방법 | |
CA2442539A1 (en) | Method and composition for solubilising a biologically active compound with low water solubility | |
Chen et al. | Protein/surfactant interfacial interactions paet 2. Electrophoretic mobility of mixed protein+ surfactant systems | |
Hu et al. | Polymersomes: Preparation and characterization | |
Péroche et al. | Synthesis and characterisation of novel nanospheres made from amphiphilic perfluoroalkylthio-β-cyclodextrins | |
Helttunen et al. | Solid lipid nanoparticles from amphiphilic calixpyrroles | |
Kumar et al. | A Review on Lyotropic Liquid Crystals and Its Potential Applications | |
Hasan et al. | Novel castor oil/water/ethanol Pickering emulsions stabilized by magnetic nanoparticles and magnetically controllable demulsification | |
Vandorpe et al. | Poly (organo phosphazene) nanoparticles surface modified with poly (ethylene oxide) | |
CA2460649A1 (en) | Novel calixarene based dispersible colloidal systems in the form of nanoparticles | |
Sahib et al. | Preparation and in-vitro hematological evaluation of chlorambucil loaded lipid nanoparticles | |
Haso et al. | Solution behaviour of a polymer with polyoxometalate inorganic molecular clusters in its main chain | |
Chopra et al. | Formulation, characterization and in vivo evaluation of self-nanoemulsifying drug delivery system for oral delivery of valsartan | |
Monnier et al. | A guide to investigating colloidal nanoparticles by cryogenic transmission electron microscopy: pitfalls and benefits |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Patent granted |
Ref document number: 118511 Country of ref document: FI |
|
MM | Patent lapsed |