FI112485B - Uusia 1,4-dihydro-4-okso-1,8-naftyridiinijohdannaisia, menetelmä niiden valmistamiseksi ja kasvaintenvastaisia aineita - Google Patents

Uusia 1,4-dihydro-4-okso-1,8-naftyridiinijohdannaisia, menetelmä niiden valmistamiseksi ja kasvaintenvastaisia aineita

Info

Publication number
FI112485B
FI112485B FI965020A FI965020A FI112485B FI 112485 B FI112485 B FI 112485B FI 965020 A FI965020 A FI 965020A FI 965020 A FI965020 A FI 965020A FI 112485 B FI112485 B FI 112485B
Authority
FI
Finland
Prior art keywords
hydrogen atom
preparation
dihydro
oxo
novel
Prior art date
Application number
FI965020A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI965020A (fi
FI965020A0 (fi
Inventor
Kyoji Tomita
Katsumi Chiba
Shigeki Kashimoto
Koh-Ichiro Shibamori
Yasunori Tsuzuki
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of FI965020A0 publication Critical patent/FI965020A0/fi
Publication of FI965020A publication Critical patent/FI965020A/fi
Application granted granted Critical
Publication of FI112485B publication Critical patent/FI112485B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI965020A 1994-06-14 1996-12-13 Uusia 1,4-dihydro-4-okso-1,8-naftyridiinijohdannaisia, menetelmä niiden valmistamiseksi ja kasvaintenvastaisia aineita FI112485B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP15657894 1994-06-14
JP19792194 1994-07-28
JP30691494 1994-11-15
JP33995694 1994-12-28
JP8170595 1995-03-13
PCT/JP1995/001110 WO1995034559A1 (fr) 1994-06-14 1995-06-06 Nouveau compose, son procede de production et agent antitumoral

Publications (3)

Publication Number Publication Date
FI965020A0 FI965020A0 (fi) 1996-12-13
FI965020A FI965020A (fi) 1996-12-16
FI112485B true FI112485B (fi) 2003-12-15

Family

ID=27524935

Family Applications (1)

Application Number Title Priority Date Filing Date
FI965020A FI112485B (fi) 1994-06-14 1996-12-13 Uusia 1,4-dihydro-4-okso-1,8-naftyridiinijohdannaisia, menetelmä niiden valmistamiseksi ja kasvaintenvastaisia aineita

Country Status (27)

Country Link
US (1) US5817669A (de)
EP (1) EP0787726B1 (de)
JP (1) JP3391796B2 (de)
KR (1) KR100350921B1 (de)
CN (1) CN1053668C (de)
AT (1) ATE209645T1 (de)
AU (1) AU679859B2 (de)
BR (1) BR9508037A (de)
CA (1) CA2192824C (de)
CZ (1) CZ292631B6 (de)
DE (1) DE69524251T2 (de)
DK (1) DK0787726T3 (de)
ES (1) ES2163512T3 (de)
FI (1) FI112485B (de)
HK (1) HK1000495A1 (de)
HU (1) HU220072B (de)
MX (1) MX9606331A (de)
NO (1) NO307255B1 (de)
NZ (1) NZ287139A (de)
PL (1) PL181867B1 (de)
PT (1) PT787726E (de)
RO (1) RO117793B1 (de)
RU (1) RU2151770C1 (de)
SI (1) SI0787726T1 (de)
SK (1) SK281341B6 (de)
TW (1) TW319769B (de)
WO (1) WO1995034559A1 (de)

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BR0212864A (pt) * 2001-09-26 2004-08-17 Bayer Pharmaceuticals Corp Derivados de 1,6-naftiridina como antidiabéticos
US6802423B2 (en) * 2002-02-20 2004-10-12 Trans Global Foods, Inc. Disposable food delivery apparatus
EP1610795A4 (de) * 2003-04-07 2007-10-24 Cylene Pharmaceuticals Inc Heterocyclische substituierte 1,4-dihydro-4-oxo-1,8-naphthpyridin-analoga
PL1666477T3 (pl) * 2003-09-10 2013-11-29 Kyorin Seiyaku Kk Pochodna kwasu 7-(4-podstawionego-3-cyklopropyloaminometylo-1- pirolidynylo)chinolonokarboksylowego
DE10352979A1 (de) * 2003-11-13 2005-06-09 Merck Patent Gmbh Pyridopyrimidinone
AU2013201203C1 (en) * 2004-03-15 2015-04-23 Sumitomo Dainippon Pharma Co., Ltd. Sns-595 and methods of using the same
CN103251589B (zh) * 2004-03-15 2015-09-30 逊尼希思制药公司 Sns-595及其使用方法
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
WO2007022474A2 (en) * 2005-08-19 2007-02-22 Cylene Pharmaceuticals, Inc. HUMAN RIBOSOMAL DNA(rDNA) AND RIBOSOMAL RNA (rRNA) NUCLEIC ACIDS AND USES THEREOF
US8580814B2 (en) * 2006-04-03 2013-11-12 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
AU2013219242C1 (en) * 2005-09-02 2016-09-22 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
CA2620915C (en) * 2005-09-02 2014-03-25 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
EP1931339B1 (de) * 2005-09-02 2018-05-16 Sunesis Pharmaceuticals, Inc. Verfahren zur verwendung von (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carbonsäure zur krebsbehandlung
CN104873502A (zh) * 2005-09-02 2015-09-02 逊尼希思制药公司 使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸治疗癌症的方法
KR20080045279A (ko) * 2005-09-14 2008-05-22 얀센 파마슈티카 엔.브이. Ｃ-ｆｍｓ 키나제 저해제로서의5-옥소-5,8-디하이드로-피리도-피리미딘
US7642270B2 (en) 2005-09-14 2010-01-05 Janssen Pharmaceutica N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
TW200800983A (en) 2005-09-14 2008-01-01 Janssen Pharmaceutica Nv 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase
CA2654876A1 (en) 2006-06-12 2007-12-21 Sunesis Pharmaceuticals, Inc. 1-8-naphthyridine compounds for the treatment of cancer
WO2008016678A2 (en) * 2006-08-01 2008-02-07 Sunesis Pharmaceuticals, Inc. Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
WO2008016702A2 (en) 2006-08-02 2008-02-07 Sunesis Pharmaceuticals, Inc. Combined use of (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1(2-thiazolyl)-1,8-naphthyridine-3-carboxylic
US8518872B2 (en) * 2007-10-22 2013-08-27 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-OXO-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid in combination therapy
WO2009075841A2 (en) * 2007-12-10 2009-06-18 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
MX2011006974A (es) * 2008-12-31 2011-11-18 Sunesis Pharmaceuticals Inc Metodo para preparar acido (+)-1,4-dihidro-7-[(3s,4s)-3-metoxi-4-( metilamino)-1-pirrolidinil]-4-oxo-1-) (2-tiazolil)-1, 8-naftiridin-3-carboxilico.
CN102405045A (zh) 2009-02-27 2012-04-04 逊尼希思制药公司 利用sns-595 治疗具有降低的brca2 活性的癌症对象的方法
UA110465C2 (en) * 2009-09-04 2016-01-12 Sunesis Pharmaceutecals Inc Stable sns-595 composition
US8470817B2 (en) * 2009-10-26 2013-06-25 Sunesis Pharmaceuticals, Inc. Compounds and methods for treatment of cancer
NZ618795A (en) 2011-05-13 2015-07-31 Array Biopharma Inc Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as trka kinase inhibitors
CN103497186B (zh) * 2013-09-24 2015-02-25 浙江司太立制药股份有限公司 含有烷氧亚氨基取代的萘啶酮羧酸衍生物及其制备方法
JP7518618B2 (ja) * 2017-03-24 2024-07-18 湧永製薬株式会社 新規ピリドンカルボン酸誘導体又はその塩

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
EP0154780B1 (de) * 1984-01-26 1990-04-11 Abbott Laboratories Antibakterielle Chinolinderivate
JPS61152682A (ja) * 1984-12-27 1986-07-11 Dainippon Pharmaceut Co Ltd ピリドンカルボン酸誘導体、そのエステルおよびその塩
JPS61251667A (ja) * 1985-04-30 1986-11-08 Otsuka Pharmaceut Co Ltd ベンゾヘテロ環化合物
PT82752B (pt) * 1985-06-13 1988-12-15 Schering Corp Processo para a preparacao de derivados policiclicos de quinolina, naftiridina e pirazinopiridina
US4851425A (en) * 1985-06-14 1989-07-25 The Upjohn Company Cyclopentapyrazole and tetrahydroindazole compounds and their use as anti-inflammatory and anti-allergic agents
JPS6233176A (ja) * 1985-08-05 1987-02-13 Toyama Chem Co Ltd １，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩
JP2704428B2 (ja) * 1988-06-15 1998-01-26 富山化学工業株式会社 キノロンカルボン酸誘導体またはその塩
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
JPH06233176A (ja) * 1993-01-29 1994-08-19 Sony Corp ビデオカメラ

Also Published As

Publication number Publication date
NZ287139A (en) 1997-07-27
PL317726A1 (en) 1997-04-28
HK1000495A1 (en) 2002-07-19
DE69524251T2 (de) 2002-07-11
NO307255B1 (no) 2000-03-06
BR9508037A (pt) 1997-09-16
TW319769B (de) 1997-11-11
EP0787726A4 (de) 1997-08-06
HU9603455D0 (en) 1997-02-28
WO1995034559A1 (fr) 1995-12-21
DE69524251D1 (de) 2002-01-10
FI965020A (fi) 1996-12-16
CZ292631B6 (cs) 2003-11-12
SK281341B6 (sk) 2001-02-12
EP0787726B1 (de) 2001-11-28
AU679859B2 (en) 1997-07-10
KR100350921B1 (ko) 2002-11-18
NO965305D0 (no) 1996-12-11
HUT75777A (en) 1997-05-28
MX9606331A (es) 1997-03-29
CA2192824C (en) 2006-11-07
NO965305L (no) 1997-02-04
CA2192824A1 (en) 1995-12-21
PL181867B1 (pl) 2001-09-28
CN1158614A (zh) 1997-09-03
CZ364396A3 (en) 1997-06-11
HU220072B (hu) 2001-10-28
DK0787726T3 (da) 2002-02-11
RO117793B1 (ro) 2002-07-30
ES2163512T3 (es) 2002-02-01
US5817669A (en) 1998-10-06
RU2151770C1 (ru) 2000-06-27
JP3391796B2 (ja) 2003-03-31
SI0787726T1 (en) 2002-04-30
AU2576795A (en) 1996-01-05
FI965020A0 (fi) 1996-12-13
EP0787726A1 (de) 1997-08-06
PT787726E (pt) 2002-04-29
SK157496A3 (en) 1997-08-06
ATE209645T1 (de) 2001-12-15
CN1053668C (zh) 2000-06-21

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Legal Events

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PC Transfer of assignment of patent

Owner name: DAINIPPON SUMITOMO PHARMA CO., LTD.

Free format text: DAINIPPON SUMITOMO PHARMA CO., LTD.

MA Patent expired