FI111946B - Kemiluminesoiva leimayhdiste, sitä sisältävä konjugaatti ja sen käyttöön perustuva diagnostinen määritys - Google Patents

Kemiluminesoiva leimayhdiste, sitä sisältävä konjugaatti ja sen käyttöön perustuva diagnostinen määritys Download PDF

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Publication number
FI111946B
FI111946B FI950764A FI950764A FI111946B FI 111946 B FI111946 B FI 111946B FI 950764 A FI950764 A FI 950764A FI 950764 A FI950764 A FI 950764A FI 111946 B FI111946 B FI 111946B
Authority
FI
Finland
Prior art keywords
analyte
chemiluminescent
assay
compound
reaction
Prior art date
Application number
FI950764A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI950764A (fi
FI950764A0 (fi
Inventor
Kastooriranganath Ramakrishnan
Original Assignee
Nichols Inst Diagnostics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Nichols Inst Diagnostics filed Critical Nichols Inst Diagnostics
Publication of FI950764A0 publication Critical patent/FI950764A0/fi
Publication of FI950764A publication Critical patent/FI950764A/fi
Application granted granted Critical
Publication of FI111946B publication Critical patent/FI111946B/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FI950764A 1992-08-21 1995-02-20 Kemiluminesoiva leimayhdiste, sitä sisältävä konjugaatti ja sen käyttöön perustuva diagnostinen määritys FI111946B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/933,478 US5395938A (en) 1992-08-21 1992-08-21 Biotinylated chemiluminescent labels and their conjugates, assays and assay kits
US93347892 1992-08-21
US9307896 1993-08-19
PCT/US1993/007896 WO1994004538A1 (fr) 1992-08-21 1993-08-19 Traceurs, conjugues, dosages, materiels de dosage chimioluminescents biotinyles

Publications (3)

Publication Number Publication Date
FI950764A0 FI950764A0 (fi) 1995-02-20
FI950764A FI950764A (fi) 1995-04-20
FI111946B true FI111946B (fi) 2003-10-15

Family

ID=25464042

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950764A FI111946B (fi) 1992-08-21 1995-02-20 Kemiluminesoiva leimayhdiste, sitä sisältävä konjugaatti ja sen käyttöön perustuva diagnostinen määritys

Country Status (12)

Country Link
US (1) US5395938A (fr)
EP (1) EP0656005B1 (fr)
JP (1) JP4068137B2 (fr)
AT (1) ATE238309T1 (fr)
AU (1) AU677017B2 (fr)
CA (1) CA2142867C (fr)
DE (1) DE69332903T2 (fr)
ES (1) ES2198417T3 (fr)
FI (1) FI111946B (fr)
NO (1) NO314308B1 (fr)
NZ (1) NZ255853A (fr)
WO (1) WO1994004538A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE111083T1 (de) * 1986-10-22 1994-09-15 Abbott Lab Chemilumineszierende acridinium- und phenantridiniumsalze.
US6087188A (en) * 1992-11-13 2000-07-11 Alk A/S Two-site immunoassay for an antibody with chemiluminescent label and biotin bound ligand
DE4407423A1 (de) * 1994-03-05 1995-09-07 Boehringer Mannheim Gmbh Entstörmittel zum Einsatz bei Immunoassays
GB2289334B (en) * 1994-05-10 1998-08-26 Molecular Light Technology Lim Enzyme linked chemiluminescent assay
US5663054A (en) * 1995-03-03 1997-09-02 Abbott Laboratories Determination of steroids by competitive immunoassay
US6056923A (en) * 1997-06-25 2000-05-02 Clmp, Inc. Dual injector for chemiluminescence immunoanalyzing system
FR2781802B1 (fr) * 1998-07-31 2001-05-11 Bio Merieux Derives satures ou insatures de l'abietane, conjugues derives et utilisations dans une composition diagnostique, un reactif et un dispositif
KR20000074881A (ko) * 1999-05-26 2000-12-15 황승용 마이크로웰을 이용한 디엔에이 돌연변이의 확인방법 및 키트
US7087395B1 (en) 2001-01-16 2006-08-08 Quest Diagnostics Investments Incorporated Vitamin D assay
US20030082179A1 (en) * 2001-07-03 2003-05-01 Hutchison James Scott Parathyroid hormone antibodies and related methods
US6723851B2 (en) * 2001-10-31 2004-04-20 Quest Diagnostics Investment Incorporated Chemiluminescent compounds and use thereof
US20050042632A1 (en) * 2002-02-13 2005-02-24 Sirna Therapeutics, Inc. Antibodies having specificity for nucleic acids
US7071311B2 (en) * 2002-02-13 2006-07-04 Sirna Therapeutics, Inc. Antibodies having specificity for 2′-C-allyl nucleic acids
EP1539702B1 (fr) * 2002-08-20 2012-04-11 Quest Diagnostics Investments Incorporated Reactifs de marquage acridinium chimioluminescents hydrophiles
US6924154B2 (en) * 2002-08-20 2005-08-02 Quest Diagnostics Investments Incorporated Hydrophilic chemilumescent acridinium labeling reagents
US20050112586A1 (en) * 2003-11-24 2005-05-26 Roland Janzen Method and composition for stabilizing liquid reagents
KR100778633B1 (ko) 2007-04-13 2007-11-28 성균관대학교산학협력단 비오틴과 비오틴-폴리에틸렌글리콜이 접합된 ｇｌｐ-1유도체, 이의 제조방법 및 이를 포함하는 약학 조성물
WO2014145619A1 (fr) 2013-03-15 2014-09-18 Hycor Biomedical, Inc. Dispositif et procédés associés de réalisation de mesures de luminescence et de fluorescence d'un échantillon

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4363759A (en) * 1978-04-10 1982-12-14 Miles Laboratories, Inc. Chemiluminescent-labeled haptens and antigens
US4656252A (en) * 1980-01-24 1987-04-07 Giese Roger W Amidobiotin compounds useful in a avidin-biotin multiple layering process
EP0082636B2 (fr) * 1981-12-11 2006-10-18 The Welsh National School of Medicine Composés et procédé pour le marquage luminescent
US4687747A (en) * 1984-07-02 1987-08-18 Mallinckrodt, Inc. Phenanthridinium ester as a labelling compound in luminometric immunoassay
DE3601031A1 (de) * 1986-01-16 1987-07-23 Behringwerke Ag Maleimido-derivate von biotin-hydrazid, verfahren zu ihrer herstellung und ihre verwendung
US4709037A (en) * 1987-02-17 1987-11-24 Hoechst Celanese Corporation Biotinylating agents
US5180828A (en) * 1990-02-09 1993-01-19 Molecular Devices Corporation Chromophoric reagents for incorporation of biotin or other haptens into macromolecules
ES2038092T1 (es) * 1990-09-07 1993-07-16 The Board Of Governors Of Wayne State University Un compuesto de dioxetano.
US5162352A (en) * 1991-08-22 1992-11-10 E. R. Squibb & Sons, Inc. 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs

Also Published As

Publication number Publication date
AU677017B2 (en) 1997-04-10
NO314308B1 (no) 2003-03-03
NZ255853A (en) 1997-05-26
CA2142867C (fr) 2010-03-16
JPH08504751A (ja) 1996-05-21
DE69332903D1 (de) 2003-05-28
NO950632D0 (no) 1995-02-20
NO950632L (no) 1995-04-07
FI950764A (fi) 1995-04-20
ATE238309T1 (de) 2003-05-15
ES2198417T3 (es) 2004-02-01
EP0656005A4 (fr) 1995-07-26
WO1994004538A1 (fr) 1994-03-03
AU5086493A (en) 1994-03-15
US5395938A (en) 1995-03-07
EP0656005B1 (fr) 2003-04-23
FI950764A0 (fi) 1995-02-20
JP4068137B2 (ja) 2008-03-26
DE69332903T2 (de) 2004-03-04
CA2142867A1 (fr) 1994-03-03
EP0656005A1 (fr) 1995-06-07

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