FI103988B1 - Process for the preparation of cephalosporin C by fermentation using Acremonium chrysogenium - Google Patents

Process for the preparation of cephalosporin C by fermentation using Acremonium chrysogenium

Info

Publication number
FI103988B1
FI103988B1 FI940778A FI940778A FI103988B1 FI 103988 B1 FI103988 B1 FI 103988B1 FI 940778 A FI940778 A FI 940778A FI 940778 A FI940778 A FI 940778A FI 103988 B1 FI103988 B1 FI 103988B1
Authority
FI
Finland
Prior art keywords
fermentation
cephalosporin
preparation
chrysogenium
acremonium
Prior art date
Application number
FI940778A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI103988B (en
FI940778A (en
FI940778A0 (en
Inventor
Thomas Bayer
Wilhelm Schramm
Wolfgang Rathscheck
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of FI940778A0 publication Critical patent/FI940778A0/en
Publication of FI940778A publication Critical patent/FI940778A/en
Application granted granted Critical
Publication of FI103988B publication Critical patent/FI103988B/en
Publication of FI103988B1 publication Critical patent/FI103988B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Soy Sauces And Products Related Thereto (AREA)

Abstract

Described is a method for the fermentative production of cephalosporin C, the fermentation solution being filtered during fermentation through a cross-flow filtration system. The filtrate obtained from the fermenter can be used again.
FI940778A 1991-08-21 1994-02-18 Process for the preparation of cephalosporin C by fermentation using Acremonium chrysogenium FI103988B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4127648A DE4127648C1 (en) 1991-08-21 1991-08-21
PCT/EP1992/001811 WO1993004188A1 (en) 1991-08-21 1992-08-08 Method for the fermentative production of cephalosporin c using acremonium chrysogenum

Publications (4)

Publication Number Publication Date
FI940778A0 FI940778A0 (en) 1994-02-18
FI940778A FI940778A (en) 1994-03-16
FI103988B FI103988B (en) 1999-10-29
FI103988B1 true FI103988B1 (en) 1999-10-29

Family

ID=6438749

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940778A FI103988B1 (en) 1991-08-21 1994-02-18 Process for the preparation of cephalosporin C by fermentation using Acremonium chrysogenium

Country Status (19)

Country Link
EP (1) EP0599891B1 (en)
JP (1) JPH07501207A (en)
CN (1) CN1045008C (en)
AT (1) ATE130038T1 (en)
AU (1) AU663519B2 (en)
CA (1) CA2116019A1 (en)
CZ (1) CZ281698B6 (en)
DE (2) DE4127648C1 (en)
DK (1) DK0599891T3 (en)
ES (1) ES2079882T3 (en)
FI (1) FI103988B1 (en)
HU (1) HU213570B (en)
NO (1) NO940565D0 (en)
PT (1) PT100796B (en)
RU (1) RU2094463C1 (en)
SK (1) SK279794B6 (en)
TW (1) TW317572B (en)
WO (1) WO1993004188A1 (en)
ZA (1) ZA926271B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100446110B1 (en) * 1997-10-24 2004-10-28 씨제이 주식회사 Cephalosporin c-producing microorganism having tolerance against high concentration of glycerol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57106683A (en) * 1980-12-24 1982-07-02 Takeda Chem Ind Ltd Method for concentrating beta-lactam antibiotic substance
DE3307095A1 (en) * 1983-03-01 1984-09-06 Degussa Ag, 6000 Frankfurt MICROBIOLOGICALLY PRODUCED L-PHENYLALANINE DEHYDROGENASE, METHOD FOR THEIR DETERMINATION AND THEIR USE
CS244333B1 (en) * 1984-11-02 1986-07-17 Jan Rakyta Method of c-cephalosporine fermentation production with utilization of fats as limitating carbonaceous substrate by means of acromonium chrysogenum strain

Also Published As

Publication number Publication date
CA2116019A1 (en) 1993-03-04
CN1071953A (en) 1993-05-12
DK0599891T3 (en) 1996-02-26
FI103988B (en) 1999-10-29
CZ281698B6 (en) 1996-12-11
NO940565L (en) 1994-02-18
TW317572B (en) 1997-10-11
HU9400463D0 (en) 1994-06-28
ZA926271B (en) 1993-04-28
EP0599891A1 (en) 1994-06-08
RU2094463C1 (en) 1997-10-27
SK279794B6 (en) 1999-03-12
HU213570B (en) 1997-08-28
DE4127648C1 (en) 1993-01-14
NO940565D0 (en) 1994-02-18
WO1993004188A1 (en) 1993-03-04
SK19794A3 (en) 1994-08-10
PT100796B (en) 1999-07-30
JPH07501207A (en) 1995-02-09
EP0599891B1 (en) 1995-11-08
HUT69767A (en) 1995-09-28
ATE130038T1 (en) 1995-11-15
ES2079882T3 (en) 1996-01-16
AU2402492A (en) 1993-03-16
FI940778A (en) 1994-03-16
DE59204277D1 (en) 1995-12-14
CZ36694A3 (en) 1994-07-13
PT100796A (en) 1993-09-30
FI940778A0 (en) 1994-02-18
CN1045008C (en) 1999-09-08
AU663519B2 (en) 1995-10-12

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