AU2402492A - Method for the fermentative production of cephalosporin c using acremonium chrysogenum - Google Patents

Method for the fermentative production of cephalosporin c using acremonium chrysogenum

Info

Publication number
AU2402492A
AU2402492A AU24024/92A AU2402492A AU2402492A AU 2402492 A AU2402492 A AU 2402492A AU 24024/92 A AU24024/92 A AU 24024/92A AU 2402492 A AU2402492 A AU 2402492A AU 2402492 A AU2402492 A AU 2402492A
Authority
AU
Australia
Prior art keywords
cephalosporin
fermentative production
acremonium chrysogenum
chrysogenum
acremonium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU24024/92A
Other versions
AU663519B2 (en
Inventor
Thomas Bayer
Wolfgang Rathscheck
Wilhelm Schramm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz GmbH
Original Assignee
Biochemie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie GmbH filed Critical Biochemie GmbH
Publication of AU2402492A publication Critical patent/AU2402492A/en
Application granted granted Critical
Publication of AU663519B2 publication Critical patent/AU663519B2/en
Assigned to BIOCHEMIE GESELLSCHAFT MBH reassignment BIOCHEMIE GESELLSCHAFT MBH Alteration of Name(s) in Register under S187 Assignors: HOECHST AKTIENGESELLSCHAFT
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Soy Sauces And Products Related Thereto (AREA)

Abstract

Described is a method for the fermentative production of cephalosporin C, the fermentation solution being filtered during fermentation through a cross-flow filtration system. The filtrate obtained from the fermenter can be used again.
AU24024/92A 1991-08-21 1992-08-08 Method for the fermentative production of cephalosporin C using acremonium chrysogenum Ceased AU663519B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4127648 1991-08-21
DE4127648A DE4127648C1 (en) 1991-08-21 1991-08-21
PCT/EP1992/001811 WO1993004188A1 (en) 1991-08-21 1992-08-08 Method for the fermentative production of cephalosporin c using acremonium chrysogenum

Publications (2)

Publication Number Publication Date
AU2402492A true AU2402492A (en) 1993-03-16
AU663519B2 AU663519B2 (en) 1995-10-12

Family

ID=6438749

Family Applications (1)

Application Number Title Priority Date Filing Date
AU24024/92A Ceased AU663519B2 (en) 1991-08-21 1992-08-08 Method for the fermentative production of cephalosporin C using acremonium chrysogenum

Country Status (19)

Country Link
EP (1) EP0599891B1 (en)
JP (1) JPH07501207A (en)
CN (1) CN1045008C (en)
AT (1) ATE130038T1 (en)
AU (1) AU663519B2 (en)
CA (1) CA2116019A1 (en)
CZ (1) CZ281698B6 (en)
DE (2) DE4127648C1 (en)
DK (1) DK0599891T3 (en)
ES (1) ES2079882T3 (en)
FI (1) FI103988B1 (en)
HU (1) HU213570B (en)
NO (1) NO940565L (en)
PT (1) PT100796B (en)
RU (1) RU2094463C1 (en)
SK (1) SK279794B6 (en)
TW (1) TW317572B (en)
WO (1) WO1993004188A1 (en)
ZA (1) ZA926271B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100446110B1 (en) * 1997-10-24 2004-10-28 씨제이 주식회사 Cephalosporin c-producing microorganism having tolerance against high concentration of glycerol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57106683A (en) * 1980-12-24 1982-07-02 Takeda Chem Ind Ltd Method for concentrating beta-lactam antibiotic substance
DE3307095A1 (en) * 1983-03-01 1984-09-06 Degussa Ag, 6000 Frankfurt MICROBIOLOGICALLY PRODUCED L-PHENYLALANINE DEHYDROGENASE, METHOD FOR THEIR DETERMINATION AND THEIR USE
CS244333B1 (en) * 1984-11-02 1986-07-17 Jan Rakyta Method of c-cephalosporine fermentation production with utilization of fats as limitating carbonaceous substrate by means of acromonium chrysogenum strain

Also Published As

Publication number Publication date
CN1071953A (en) 1993-05-12
ZA926271B (en) 1993-04-28
NO940565D0 (en) 1994-02-18
FI103988B (en) 1999-10-29
CZ281698B6 (en) 1996-12-11
WO1993004188A1 (en) 1993-03-04
AU663519B2 (en) 1995-10-12
SK19794A3 (en) 1994-08-10
PT100796A (en) 1993-09-30
DK0599891T3 (en) 1996-02-26
HUT69767A (en) 1995-09-28
FI940778A0 (en) 1994-02-18
HU213570B (en) 1997-08-28
EP0599891A1 (en) 1994-06-08
ES2079882T3 (en) 1996-01-16
FI940778A (en) 1994-03-16
NO940565L (en) 1994-02-18
RU2094463C1 (en) 1997-10-27
JPH07501207A (en) 1995-02-09
DE4127648C1 (en) 1993-01-14
EP0599891B1 (en) 1995-11-08
CA2116019A1 (en) 1993-03-04
CN1045008C (en) 1999-09-08
CZ36694A3 (en) 1994-07-13
PT100796B (en) 1999-07-30
FI103988B1 (en) 1999-10-29
ATE130038T1 (en) 1995-11-15
TW317572B (en) 1997-10-11
HU9400463D0 (en) 1994-06-28
SK279794B6 (en) 1999-03-12
DE59204277D1 (en) 1995-12-14

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Legal Events

Date Code Title Description
PC Assignment registered

Owner name: BIOCHEMIE GESELLSCHAFT MBH

Free format text: FORMER OWNER WAS: HOECHST AKTIENGESELLSCHAFT

MK14 Patent ceased section 143(a) (annual fees not paid) or expired