FI102538B1 - Syntes av LH-RH-analoger medelst temporär minimal skydd - Google Patents

Syntes av LH-RH-analoger medelst temporär minimal skydd

Info

Publication number
FI102538B1
FI102538B1 FI910788A FI910788A FI102538B1 FI 102538 B1 FI102538 B1 FI 102538B1 FI 910788 A FI910788 A FI 910788A FI 910788 A FI910788 A FI 910788A FI 102538 B1 FI102538 B1 FI 102538B1
Authority
FI
Finland
Prior art keywords
synthesis
analogs
transient
minimal protection
amino
Prior art date
Application number
FI910788A
Other languages
English (en)
Finnish (fi)
Other versions
FI102538B (sv
FI910788A0 (fi
FI910788A (fi
Inventor
Jr John J Nestor
Natalie L Mcclure
Humberto Arzeno
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of FI910788A0 publication Critical patent/FI910788A0/fi
Publication of FI910788A publication Critical patent/FI910788A/fi
Application granted granted Critical
Publication of FI102538B1 publication Critical patent/FI102538B1/sv
Publication of FI102538B publication Critical patent/FI102538B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/065—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for hydroxy functions, not being part of carboxy functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Bipolar Integrated Circuits (AREA)
  • Amplifiers (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Escalators And Moving Walkways (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Golf Clubs (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Variable-Direction Aerials And Aerial Arrays (AREA)
  • Fuses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • Semiconductor Integrated Circuits (AREA)
FI910788A 1990-02-20 1991-02-19 Syntes av LH-RH-analoger medelst temporär minimal skydd FI102538B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48242890A 1990-02-20 1990-02-20
US48242890 1990-02-20

Publications (4)

Publication Number Publication Date
FI910788A0 FI910788A0 (fi) 1991-02-19
FI910788A FI910788A (fi) 1991-08-21
FI102538B1 true FI102538B1 (sv) 1998-12-31
FI102538B FI102538B (sv) 1998-12-31

Family

ID=23916033

Family Applications (1)

Application Number Title Priority Date Filing Date
FI910788A FI102538B (sv) 1990-02-20 1991-02-19 Syntes av LH-RH-analoger medelst temporär minimal skydd

Country Status (18)

Country Link
EP (1) EP0443532B1 (sv)
JP (1) JP2927978B2 (sv)
KR (1) KR0152276B1 (sv)
AT (1) ATE107931T1 (sv)
AU (1) AU639751B2 (sv)
CA (1) CA2036657C (sv)
DE (1) DE69102659T2 (sv)
DK (1) DK0443532T3 (sv)
ES (1) ES2057624T3 (sv)
FI (1) FI102538B (sv)
HK (1) HK43097A (sv)
HU (1) HU208158B (sv)
IE (1) IE71945B1 (sv)
NO (1) NO309428B1 (sv)
NZ (1) NZ237159A (sv)
PH (1) PH31062A (sv)
PT (1) PT96807B (sv)
ZA (1) ZA911233B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104231055A (zh) 2013-06-18 2014-12-24 深圳翰宇药业股份有限公司 加尼瑞克前体以及由其制备醋酸加尼瑞克的方法
KR101971418B1 (ko) * 2017-06-30 2019-04-24 애니젠 주식회사 고세렐린의 제조 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4301066A (en) * 1980-05-08 1981-11-17 American Home Products Corp. Preparation of (D-Trp 6)-LH-RH via the heptapeptide H-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
US4632979A (en) * 1984-06-18 1986-12-30 Tulane Educational Fund Therapeutic LHRH analogs
US4677193A (en) * 1985-02-22 1987-06-30 The Salk Institute For Biological Studies Peptides containing an aliphatic-aromatic ketone side chain
US4800191A (en) * 1987-07-17 1989-01-24 Schally Andrew Victor LHRH antagonists

Also Published As

Publication number Publication date
DK0443532T3 (da) 1994-07-25
NZ237159A (en) 1992-11-25
PT96807A (pt) 1991-10-31
NO910664D0 (no) 1991-02-19
NO309428B1 (no) 2001-01-29
NO910664L (no) 1991-08-21
AU639751B2 (en) 1993-08-05
FI102538B (sv) 1998-12-31
PT96807B (pt) 1998-07-31
EP0443532B1 (en) 1994-06-29
PH31062A (en) 1998-02-05
ZA911233B (en) 1992-10-28
EP0443532A2 (en) 1991-08-28
CA2036657C (en) 2003-02-11
HK43097A (en) 1997-04-11
HU910543D0 (en) 1991-09-30
AU7117691A (en) 1991-08-22
DE69102659T2 (de) 1995-02-23
HUT57234A (en) 1991-11-28
KR0152276B1 (ko) 1998-10-01
DE69102659D1 (de) 1994-08-04
HU208158B (en) 1993-08-30
IE910556A1 (en) 1991-08-28
JP2927978B2 (ja) 1999-07-28
JPH04211096A (ja) 1992-08-03
EP0443532A3 (en) 1992-02-26
KR910021411A (ko) 1991-12-20
FI910788A0 (fi) 1991-02-19
IE71945B1 (en) 1997-03-12
ATE107931T1 (de) 1994-07-15
CA2036657A1 (en) 1991-08-21
ES2057624T3 (es) 1994-10-16
FI910788A (fi) 1991-08-21

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