ES8802362A1 - Procedimiento para la obtencion de derivados de la 13-beta-milbemicina - Google Patents

Procedimiento para la obtencion de derivados de la 13-beta-milbemicina

Info

Publication number
ES8802362A1
ES8802362A1 ES556156A ES556156A ES8802362A1 ES 8802362 A1 ES8802362 A1 ES 8802362A1 ES 556156 A ES556156 A ES 556156A ES 556156 A ES556156 A ES 556156A ES 8802362 A1 ES8802362 A1 ES 8802362A1
Authority
ES
Spain
Prior art keywords
milbemycin
formula
beta
group
milbemycin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES556156A
Other languages
English (en)
Spanish (es)
Other versions
ES556156A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8802362A1 publication Critical patent/ES8802362A1/es
Publication of ES556156A0 publication Critical patent/ES556156A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES556156A 1984-12-14 1986-06-02 Procedimiento para la obtencion de derivados de la 13-beta-milbemicina Expired ES8802362A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH594084 1984-12-14
CH228985 1985-05-30

Publications (2)

Publication Number Publication Date
ES8802362A1 true ES8802362A1 (es) 1988-05-16
ES556156A0 ES556156A0 (es) 1988-05-16

Family

ID=25690025

Family Applications (3)

Application Number Title Priority Date Filing Date
ES556155A Expired ES8801285A1 (es) 1984-12-14 1986-06-02 Procedimiento para la obtencion de derivados de la 13-beta-milbemicina
ES556157A Expired ES8802156A1 (es) 1984-12-14 1986-06-02 Procedimiento para la obtencion de derivados de la 13-beta-milbemicina
ES556156A Expired ES8802362A1 (es) 1984-12-14 1986-06-02 Procedimiento para la obtencion de derivados de la 13-beta-milbemicina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES556155A Expired ES8801285A1 (es) 1984-12-14 1986-06-02 Procedimiento para la obtencion de derivados de la 13-beta-milbemicina
ES556157A Expired ES8802156A1 (es) 1984-12-14 1986-06-02 Procedimiento para la obtencion de derivados de la 13-beta-milbemicina

Country Status (18)

Country Link
US (1) US4959386A (en:Method)
EP (1) EP0186043B1 (en:Method)
JP (1) JPH0689003B2 (en:Method)
CN (1) CN85109493A (en:Method)
AU (1) AU590529B2 (en:Method)
BR (1) BR8506253A (en:Method)
CA (1) CA1261824A (en:Method)
DE (1) DE3583285D1 (en:Method)
DK (1) DK578185A (en:Method)
ES (3) ES8801285A1 (en:Method)
FI (1) FI854906A7 (en:Method)
GB (1) GB2168345B (en:Method)
GR (1) GR852980B (en:Method)
HU (1) HUT39569A (en:Method)
IL (1) IL77310A (en:Method)
NZ (1) NZ214553A (en:Method)
PT (1) PT81669B (en:Method)
ZW (1) ZW23185A1 (en:Method)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU574852B2 (en) * 1984-10-26 1988-07-14 Sankyo Company Limited 13 - acyloxy - 5 - ketomilbemycin derivatives and preparation of 13 - hydroxy - 5 - ketomilbemycin derivatives
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use
AR243191A1 (es) * 1986-03-25 1993-07-30 Sankyo Co Procedimiento para preparar compuestos de macrolida
EP0253767A1 (de) * 1986-07-02 1988-01-20 Ciba-Geigy Ag Parasitizide und Insektizide
DE3778768D1 (de) * 1986-07-02 1992-06-11 Ciba Geigy Ag Pestizide.
US4897416A (en) * 1987-02-18 1990-01-30 Ciba-Geigy Corporation Insecticides and parasiticides
GB8804440D0 (en) * 1988-02-25 1988-03-23 Pfizer Ltd Antiparasitic agents
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
JPH085894B2 (ja) * 1990-03-01 1996-01-24 三共株式会社 ミルベマイシンエーテル誘導体
US5290804A (en) * 1991-05-01 1994-03-01 Merck & Co., Inc. Anthelmintic milbemycin analogs of novel microorganisms
AU666750B2 (en) * 1992-09-01 1996-02-22 Novartis Animal Health K.K. Novel processes for the production of 13-ether derivatives of milbemycins, and novel intermediates therefor
BR9607262A (pt) 1995-02-24 1997-12-30 Norvatis Ag Novartis Sa Novart Composição para controlar parasitas
AT501406A1 (de) * 1997-12-23 2006-08-15 Syngenta Participations Ag Verfahren zur bekämpfung von mollusken
JP4373080B2 (ja) * 2002-12-24 2009-11-25 三井化学アグロ株式会社 ミルベマイシン類の精製法
CN101514220B (zh) * 2009-04-02 2012-07-11 浙江大学 具有农药活性的弥拜霉素衍生物及其用途

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
NZ186851A (en) * 1977-04-11 1984-12-14 Merck & Co Inc Glycosyloxy derivatives of milbemycin and parasiticidal compositions
US4093629A (en) * 1977-04-11 1978-06-06 Merck & Co., Inc. Derivatives of antibiotic substance milbemycin and processes therefor
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
PH16612A (en) * 1977-12-19 1983-11-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
US4289760A (en) * 1980-05-02 1981-09-15 Merck & Co., Inc. 23-Keto derivatives of C-076 compounds
US4285963A (en) * 1980-08-07 1981-08-25 Merck & Co., Inc. Novel derivatives of C-076 compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4333925A (en) * 1981-05-11 1982-06-08 Merck & Co., Inc. Derivatives of C-076 compounds
US4412991A (en) * 1981-08-28 1983-11-01 Merck & Co., Inc. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use
US4457920A (en) * 1981-09-03 1984-07-03 Merck & Co., Inc. 4a-Substituted avermectin compounds
NZ201681A (en) * 1981-09-03 1985-11-08 Merck & Co Inc Avermectin derivatives and parasiticidal compositions
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
US4427663A (en) * 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
JPS5920285A (ja) * 1982-07-23 1984-02-01 Sankyo Co Ltd ミルベマイシンｄの５−二塩基酸エステル誘導体及びその塩
JPS59108785A (ja) * 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の５−オキシム誘導体
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use

Also Published As

Publication number Publication date
US4959386A (en) 1990-09-25
FI854906A7 (fi) 1986-06-15
IL77310A (en) 1989-07-31
DK578185A (da) 1986-06-15
ES556157A0 (es) 1988-04-01
ZW23185A1 (en) 1987-07-16
GB8530419D0 (en) 1986-01-22
JPH0689003B2 (ja) 1994-11-09
BR8506253A (pt) 1986-08-26
EP0186043A1 (de) 1986-07-02
ES8802156A1 (es) 1988-04-01
HUT39569A (en) 1986-10-29
ES556155A0 (es) 1987-12-16
EP0186043B1 (de) 1991-06-19
GB2168345A (en) 1986-06-18
NZ214553A (en) 1989-06-28
CN85109493A (zh) 1986-12-17
DK578185D0 (da) 1985-12-13
DE3583285D1 (de) 1991-07-25
PT81669B (en) 1987-10-09
PT81669A (en) 1986-01-01
ES8801285A1 (es) 1987-12-16
AU5119185A (en) 1986-06-26
AU590529B2 (en) 1989-11-09
GR852980B (en:Method) 1986-04-08
FI854906A0 (fi) 1985-12-11
JPS61180787A (ja) 1986-08-13
GB2168345B (en) 1988-05-25
ES556156A0 (es) 1988-05-16
CA1261824A (en) 1989-09-26

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