ES8802320A1 - Procedimiento para la obtencion de derivados de piridazo-(1,2-a)(1,2)diacepina - Google Patents

Procedimiento para la obtencion de derivados de piridazo-(1,2-a)(1,2)diacepina

Info

Publication number
ES8802320A1
ES8802320A1 ES557504A ES557504A ES8802320A1 ES 8802320 A1 ES8802320 A1 ES 8802320A1 ES 557504 A ES557504 A ES 557504A ES 557504 A ES557504 A ES 557504A ES 8802320 A1 ES8802320 A1 ES 8802320A1
Authority
ES
Spain
Prior art keywords
pyridazo
aralkyl
alkyl
phosphonic
diazepine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557504A
Other languages
English (en)
Other versions
ES557504A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES557504A0 publication Critical patent/ES557504A0/es
Publication of ES8802320A1 publication Critical patent/ES8802320A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom

Abstract

UN PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE FORMULA GENERAL (I), Y SUS SALES, QUE COMPRENDE: A) REDUCIR UN COMPUESTO DE FORMULA GENERAL (II) MEDIANTE UN COMPLEJO DE BORANO (BORANO/TETRAHIDROFURANO, BORANO/SULFURO DE DIMETILO, BORANO/N,N-DIETILANILINA, ETC.), EN UN DISOLVENTE ORGANICO INERTE; Y B) SI SE DESEA, SEPARAR UNA MEZCLA DE RACEMATOS DIASTEREOISOMERICOS CON METODOS CONOCIDOS (POR EJEMPLO, CROMATOGRAFIA SOBRE GEL DE SILICE); Y/O C) RESOLVER UN RACEMATO MEDIANTE TRATAMIENTO CON UN ACIDO O BASE OPTICAMENTE ACTIVOS, SEPARAR LAS SALES OPTICAMENTE ACTIVAS MEDIANTE CRISTALIZACION FRACCIONADA Y LIBERAR LOS COMPUESTOS OPTICAMENTE UNIFORMES CON METODOS CONVENCIONALES; Y D) CONVERTIR EL COMPUESTO DE FORMULA (I) EN UNA SAL FARMACEUTICAMENTE ACEPTABLE. DE APLICACION FARMACOLOGICA COMO ANTIDEPRESIVO.
ES557504A 1985-07-01 1987-04-15 Procedimiento para la obtencion de derivados de piridazo-(1,2-a)(1,2)diacepina Expired ES8802320A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858516604A GB8516604D0 (en) 1985-07-01 1985-07-01 Pyridazodiazepine derivatives

Publications (2)

Publication Number Publication Date
ES557504A0 ES557504A0 (es) 1988-05-01
ES8802320A1 true ES8802320A1 (es) 1988-05-01

Family

ID=10581602

Family Applications (1)

Application Number Title Priority Date Filing Date
ES557504A Expired ES8802320A1 (es) 1985-07-01 1987-04-15 Procedimiento para la obtencion de derivados de piridazo-(1,2-a)(1,2)diacepina

Country Status (6)

Country Link
JP (1) JPS625984A (es)
KR (1) KR870001226A (es)
ES (1) ES8802320A1 (es)
GB (2) GB8516604D0 (es)
GR (1) GR861710B (es)
ZA (1) ZA864718B (es)

Also Published As

Publication number Publication date
ES557504A0 (es) 1988-05-01
GB8609591D0 (en) 1986-05-21
GR861710B (en) 1986-11-03
KR870001226A (ko) 1987-03-12
ZA864718B (en) 1987-02-25
GB8516604D0 (en) 1985-08-07
JPS625984A (ja) 1987-01-12

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