ES8801729A1 - Un ensayo inmunometrio para proteina p21ras humana - Google Patents
Un ensayo inmunometrio para proteina p21ras humanaInfo
- Publication number
- ES8801729A1 ES8801729A1 ES557386A ES557386A ES8801729A1 ES 8801729 A1 ES8801729 A1 ES 8801729A1 ES 557386 A ES557386 A ES 557386A ES 557386 A ES557386 A ES 557386A ES 8801729 A1 ES8801729 A1 ES 8801729A1
- Authority
- ES
- Spain
- Prior art keywords
- antibodies
- ras oncogene
- p21ras
- protein family
- peptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Abstract
METODO DE ENSAYO INMUNOMETRICO PARA PROTEINA DEL TIPO P21 RAS HUMANA. CONSISTE EN SOMETER LA MUESTRA OBJETO DE ANALISIS A UN ENSAYO HETEROGENEO CONSISTENTE EN LA FORMACION DE UN COMPLEJO INMUNE ENTRE LA PROTEINA Y UN ANTICUERPO SELECTIVO EN FORMA CRUZADA CON LAS OTRAS PROTEINAS, Y DETERMINACION DEL CITADO COMPLEJO POR CONTACTO CON UN SEGUNDO ANTICUERPO QUE SE SEÑALA CON UNA ENZIMA. TIENE APLICACION EN DIAGNOSIS PARA LA DETECCION DE CELULAS TUMORALES MAMARIAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73941685A | 1985-05-30 | 1985-05-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES557386A0 ES557386A0 (es) | 1988-02-16 |
ES8801729A1 true ES8801729A1 (es) | 1988-02-16 |
Family
ID=24972206
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES555435A Expired ES8800274A1 (es) | 1985-05-30 | 1986-05-29 | Un procedimiento para la preparacion de un polipeptido-c-terminal p21ras |
ES557386A Expired ES8801729A1 (es) | 1985-05-30 | 1987-02-13 | Un ensayo inmunometrio para proteina p21ras humana |
ES557387A Expired ES8802457A1 (es) | 1985-05-30 | 1987-02-13 | Un procedimiento para la preparacion de polipeptidos inmunogenicos |
ES557385A Expired ES8900246A1 (es) | 1985-05-30 | 1987-02-13 | Un procedimiento para la preparacion de anticuerpos especificos para uno de los miembros de la familia p 2 de proteinas |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES555435A Expired ES8800274A1 (es) | 1985-05-30 | 1986-05-29 | Un procedimiento para la preparacion de un polipeptido-c-terminal p21ras |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES557387A Expired ES8802457A1 (es) | 1985-05-30 | 1987-02-13 | Un procedimiento para la preparacion de polipeptidos inmunogenicos |
ES557385A Expired ES8900246A1 (es) | 1985-05-30 | 1987-02-13 | Un procedimiento para la preparacion de anticuerpos especificos para uno de los miembros de la familia p 2 de proteinas |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0203587A3 (es) |
JP (1) | JPS61289099A (es) |
AU (1) | AU600439B2 (es) |
DK (1) | DK253386A (es) |
ES (4) | ES8800274A1 (es) |
NO (1) | NO862144L (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5733738A (en) * | 1983-08-17 | 1998-03-31 | Ligand Pharmaceuticals | Polypeptide-induced monoclonal receptors to protein ligands |
US6200764B1 (en) | 1985-01-29 | 2001-03-13 | Bayer Corporation | Detection, quantitation and classification of ras proteins in body fluids and tissues |
US5084380A (en) * | 1985-01-29 | 1992-01-28 | Applied Biotechnology | Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins |
AU615876B2 (en) * | 1985-08-21 | 1991-10-17 | Oncogene Science, Inc. | Immunoassay for the detection of Oncogene encoded products |
DK354487A (da) * | 1986-07-11 | 1988-01-12 | Noboru Yanaihara | Oncogen-relaterede peptider |
JPS6374492A (ja) * | 1986-09-18 | 1988-04-04 | Hiroshi Shiyuku | モノクロ−ナル抗体 |
US5112737A (en) * | 1988-02-22 | 1992-05-12 | Applied Biotechnology, Inc. | Monoclonal antibodies against activated ras proteins with amino acid mutations at position 13 of the protein |
WO1989010375A1 (en) * | 1988-04-22 | 1989-11-02 | E.I. Du Pont De Nemours And Company | Monoclonal antibodies specific for the harvey, kirsten and n ras proteins and their use as diagnostic reagents |
DE68928470T2 (de) * | 1988-08-12 | 1998-04-16 | Ligand Pharm Inc | Polypeptid-induzierte monoklonale Rezeptoren gegen Proteinliganden |
CA2044333A1 (en) * | 1990-06-12 | 1991-12-13 | Jackson B. Gibbs | Chemotherapeutic agents |
US5965539A (en) * | 1993-05-18 | 1999-10-12 | Univeristy Of Pittsburgh | Inhibitors of prenyl transferases |
US5705686A (en) * | 1993-05-18 | 1998-01-06 | University Of Pittsburgh | Inhibition of farnesyl transferase |
US5834434A (en) * | 1993-05-18 | 1998-11-10 | University Of Pittsburgh | Inhibitors of farnesyltransferase |
US5602098A (en) * | 1993-05-18 | 1997-02-11 | University Of Pittsburgh | Inhibition of farnesyltransferase |
US6011175A (en) * | 1993-05-18 | 2000-01-04 | University Of Pittsburgh | Inhibition of farnesyltransferase |
US5840683A (en) * | 1995-09-21 | 1998-11-24 | Innapharma, Inc. | Peptides inhibiting the oncogenic action of p21 ras |
US5910478A (en) * | 1995-09-21 | 1999-06-08 | Innapharma, Inc. | Peptidomimetics inhibiting the oncogenic action of p21 ras |
US6221865B1 (en) | 1995-11-06 | 2001-04-24 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
US6310095B1 (en) | 1995-11-06 | 2001-10-30 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
US6204293B1 (en) | 1995-11-06 | 2001-03-20 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
US6693123B2 (en) | 1995-11-06 | 2004-02-17 | University Of Pittsburgh | Inhibitors of protein isoprenyl transferases |
US20020156257A1 (en) * | 2001-03-29 | 2002-10-24 | Chunhua Yan | Isolated human Ras-like proteins, nucleic acid molecules encoding these human Ras-like proteins, and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE56509B1 (en) * | 1982-11-04 | 1991-08-28 | Univ California | Methods for oncogenic detection |
AU2650984A (en) * | 1983-02-14 | 1984-08-30 | Arup Sen | Synthetic polypeptides from viral oncogenes |
ZA84617B (en) * | 1983-02-14 | 1984-09-26 | Arup Sen | Synthetic polypeptides from viryl oncogenes |
CA1219232A (en) * | 1983-08-17 | 1987-03-17 | Richard A. Lerner | Polypeptide-induced monoclonal receptors to protein ligands |
US4798787A (en) * | 1984-09-19 | 1989-01-17 | Cetus Corporation | Peptide antibodies and their use in detecting oncogene products |
-
1986
- 1986-05-28 EP EP86107244A patent/EP0203587A3/en not_active Withdrawn
- 1986-05-29 NO NO862144A patent/NO862144L/no unknown
- 1986-05-29 DK DK253386A patent/DK253386A/da not_active Application Discontinuation
- 1986-05-29 ES ES555435A patent/ES8800274A1/es not_active Expired
- 1986-05-29 JP JP61124628A patent/JPS61289099A/ja active Pending
- 1986-05-29 AU AU58058/86A patent/AU600439B2/en not_active Expired - Fee Related
-
1987
- 1987-02-13 ES ES557386A patent/ES8801729A1/es not_active Expired
- 1987-02-13 ES ES557387A patent/ES8802457A1/es not_active Expired
- 1987-02-13 ES ES557385A patent/ES8900246A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES557386A0 (es) | 1988-02-16 |
AU600439B2 (en) | 1990-08-16 |
AU5805886A (en) | 1986-12-04 |
ES557385A0 (es) | 1989-05-16 |
DK253386D0 (da) | 1986-05-29 |
ES557387A0 (es) | 1988-07-01 |
ES555435A0 (es) | 1987-10-16 |
JPS61289099A (ja) | 1986-12-19 |
EP0203587A3 (en) | 1989-08-09 |
ES8900246A1 (es) | 1989-05-16 |
ES8802457A1 (es) | 1988-07-01 |
NO862144L (no) | 1986-12-01 |
ES8800274A1 (es) | 1987-10-16 |
DK253386A (da) | 1986-12-01 |
EP0203587A2 (en) | 1986-12-03 |
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