ES8801182A1 - Un procedimiento para la preparacion de derivados aminicos - Google Patents
Un procedimiento para la preparacion de derivados aminicosInfo
- Publication number
- ES8801182A1 ES8801182A1 ES557019A ES557019A ES8801182A1 ES 8801182 A1 ES8801182 A1 ES 8801182A1 ES 557019 A ES557019 A ES 557019A ES 557019 A ES557019 A ES 557019A ES 8801182 A1 ES8801182 A1 ES 8801182A1
- Authority
- ES
- Spain
- Prior art keywords
- represent
- phenyl
- halogen
- alkyl
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
METODO DE PREPARAR DERIVADOS AMINICOS. CONSISTE EN HACER REACCIONAR COMPUESTOS DE FORMULAS AR(CH2)2NHR9 Y R10NHCR2R3CR4R5Y1 CON UN AGENTE ALQUILANTE, EN UN DISOLVENTE Y EN UN INTERVALO DE TEMPERATURAS ENTRE C5 Y 100JC; Y ELIMINAR CUALQUIER GRUPO PROTECTOR PRESENTE EN UN INTERMEDIO DE FORMULA (II), PARA OBTENER DERIVADOS AMINICOS DE FORMULA (I), DONDE R1 ES HALOGENO O UN GRUPO METILO, ETILO, N-PROPILO O N-BUTILO; R2, R3, R4 Y R5 SON CADA UNO DE ELLOS, H, O UNO DE ELLOS ES UN GRUPO METILO O ETILO; X ES UNA CADENA ALQUILENO DE C 4 A 7 Y OTROS; E Y ES UN ANILLO FENILICO Y OTROS. TIENEN APLICACIONES FARMACEUTICAS PARA DISMINUIR LA RESISTENCIA VASCULAR.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858500926A GB8500926D0 (en) | 1985-01-15 | 1985-01-15 | Chemical compounds |
GB858500927A GB8500927D0 (en) | 1985-01-15 | 1985-01-15 | Chemical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
ES557019A0 ES557019A0 (es) | 1987-12-16 |
ES8801182A1 true ES8801182A1 (es) | 1987-12-16 |
Family
ID=26288665
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES550874A Expired ES8704873A1 (es) | 1985-01-15 | 1986-01-14 | Un procedimiento para la preparacion de 3,4-dihidroxifemetilamino derivados 2-ustituidos. |
ES557019A Expired ES8801182A1 (es) | 1985-01-15 | 1986-08-14 | Un procedimiento para la preparacion de derivados aminicos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES550874A Expired ES8704873A1 (es) | 1985-01-15 | 1986-01-14 | Un procedimiento para la preparacion de 3,4-dihidroxifemetilamino derivados 2-ustituidos. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5023378A (es) |
EP (1) | EP0188361B1 (es) |
AU (1) | AU587217B2 (es) |
CA (1) | CA1281036C (es) |
DE (1) | DE3677787D1 (es) |
DK (1) | DK17386A (es) |
ES (2) | ES8704873A1 (es) |
IL (1) | IL77594A (es) |
NZ (1) | NZ214823A (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI864680A (fi) * | 1985-11-20 | 1987-05-21 | Fisons Plc | Aromatiska foereningar. |
EP0314725A1 (en) * | 1987-05-19 | 1989-05-10 | FISONS plc | 2-(3,4-dihydroxyphenyl)ethylamines, their preparation and use as pharmaceutical |
US5281623A (en) * | 1990-08-27 | 1994-01-25 | Eli Lilly And Company | Method for treating inflammation |
US5441984A (en) * | 1994-01-06 | 1995-08-15 | Eli Lilly And Company | Urea, thiourea and guanidine derivatives |
BR9708632A (pt) | 1996-04-09 | 2000-01-18 | Nps Pharma Inc | Composto calcilìticos |
US6818660B2 (en) | 1996-04-09 | 2004-11-16 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
US7202261B2 (en) | 1996-12-03 | 2007-04-10 | Nps Pharmaceuticals, Inc. | Calcilytic compounds |
TW483881B (en) | 1996-12-03 | 2002-04-21 | Nps Pharma Inc | Calcilytic compounds |
US20200223826A1 (en) * | 2017-07-25 | 2020-07-16 | The Board Of Trustees Of The Leland Stanford Junior University | Glucose-6-Phosphate Dehydrogenase (G6PD)-Modulating Agents And Methods Of Treating G6PD Deficiency |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2653977A (en) * | 1953-09-29 | Chxnx | ||
GB987438A (en) * | 1961-10-10 | 1965-03-31 | Frosst & Co Charles E | N,n-disubstituted-1,3-diamino-propanes and 2-propanols |
NL130078C (es) * | 1963-06-11 | |||
ES374103A1 (es) * | 1968-12-03 | 1971-12-16 | Boehringer Sohn Ingelheim | Procedimiento para la preparacion de polimetilendiaminas sustituidas. |
US3789072A (en) * | 1970-04-22 | 1974-01-29 | Squibb & Sons Inc | Carboxamides |
US4024281A (en) * | 1972-05-26 | 1977-05-17 | Smithkline Corporation | N,N-bis[2-(3-substituted-4-hydroxyphenyl)-ethyl or -2-hydroxyethyl]-polymethylenediamines |
DK449974A (es) * | 1973-08-31 | 1975-04-28 | Sandoz Ag | |
US4155907A (en) * | 1976-08-16 | 1979-05-22 | The Dow Chemical Company | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines |
DE3263531D1 (en) * | 1981-08-05 | 1985-06-20 | Fisons Plc | Amine derivatives, processes for their production and pharmaceutical compositions containing them |
AU561190B2 (en) * | 1983-01-21 | 1987-04-30 | Fisons Plc | Aromatic amines |
US4657929A (en) * | 1983-10-25 | 1987-04-14 | Fisons Plc | Compounds |
DE3484048D1 (de) * | 1983-10-25 | 1991-03-07 | Fisons Plc | Phenylethylamine, verfahren zu deren herstellung und diese enthaltende zusammensetzungen. |
-
1986
- 1986-01-14 DK DK17386A patent/DK17386A/da not_active Application Discontinuation
- 1986-01-14 NZ NZ214823A patent/NZ214823A/xx unknown
- 1986-01-14 ES ES550874A patent/ES8704873A1/es not_active Expired
- 1986-01-14 EP EP86300195A patent/EP0188361B1/en not_active Expired - Lifetime
- 1986-01-14 AU AU52289/86A patent/AU587217B2/en not_active Ceased
- 1986-01-14 CA CA000499567A patent/CA1281036C/en not_active Expired - Fee Related
- 1986-01-14 IL IL77594A patent/IL77594A/xx not_active IP Right Cessation
- 1986-01-14 DE DE8686300195T patent/DE3677787D1/de not_active Expired - Fee Related
- 1986-08-14 ES ES557019A patent/ES8801182A1/es not_active Expired
-
1989
- 1989-10-06 US US07/418,208 patent/US5023378A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5023378A (en) | 1991-06-11 |
ES8704873A1 (es) | 1987-04-16 |
AU587217B2 (en) | 1989-08-10 |
CA1281036C (en) | 1991-03-05 |
AU5228986A (en) | 1986-07-24 |
DK17386D0 (da) | 1986-01-14 |
NZ214823A (en) | 1989-08-29 |
DE3677787D1 (de) | 1991-04-11 |
ES557019A0 (es) | 1987-12-16 |
EP0188361B1 (en) | 1991-03-06 |
ES550874A0 (es) | 1987-04-16 |
IL77594A (en) | 1989-12-15 |
DK17386A (da) | 1986-07-16 |
EP0188361A1 (en) | 1986-07-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970401 |