ES8800603A1 - Un metodo para producir anticuerpos monoclonales - Google Patents

Un metodo para producir anticuerpos monoclonales

Info

Publication number
ES8800603A1
ES8800603A1 ES554206A ES554206A ES8800603A1 ES 8800603 A1 ES8800603 A1 ES 8800603A1 ES 554206 A ES554206 A ES 554206A ES 554206 A ES554206 A ES 554206A ES 8800603 A1 ES8800603 A1 ES 8800603A1
Authority
ES
Spain
Prior art keywords
tumour
antigen
associated antigen
range
ycr010
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554206A
Other languages
English (en)
Other versions
ES554206A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hybritech Inc
Original Assignee
Hybritech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybritech Inc filed Critical Hybritech Inc
Publication of ES554206A0 publication Critical patent/ES554206A0/es
Publication of ES8800603A1 publication Critical patent/ES8800603A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1063—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from stomach or intestines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ANTICUERPOS MONOCLONALES. CONSISTE EN INMUNIZAR UN RATON U OTRO HOSPEDANTE ADECUADO CON UN ANTIGENO PURIFICADO DERIVADO DE UNA FUENTE DE TEJIDO HUMANO NORMAL O TEJIDO HUMANO TUMORAL; FUSIONAR CELULAS DE BAZO DEL RATON U HOSPEDANTE ASI INMUNIZADO CON CELULAS DE MIELOMA DE RATON; CULTIVAR LAS LINEAS DE CELULAS HIBRIDAS ASI FORMADAS EN UN MEDIO ADECUADO; SELECCIONAR Y CLONAR LINEAS Y RECUPERAR EL ANTICUERPO MONOCLONAL ASI OBTENIDO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA LA DETECCION, EL DIAGNOSTICO Y EL TRATAMIENTO DE CANCER EN SERES HUMANOS.
ES554206A 1985-04-22 1986-04-21 Un metodo para producir anticuerpos monoclonales Expired ES8800603A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72620185A 1985-04-22 1985-04-22

Publications (2)

Publication Number Publication Date
ES554206A0 ES554206A0 (es) 1987-11-16
ES8800603A1 true ES8800603A1 (es) 1987-11-16

Family

ID=24917619

Family Applications (1)

Application Number Title Priority Date Filing Date
ES554206A Expired ES8800603A1 (es) 1985-04-22 1986-04-21 Un metodo para producir anticuerpos monoclonales

Country Status (7)

Country Link
EP (1) EP0199586A3 (es)
JP (1) JPS61282096A (es)
AU (1) AU5637086A (es)
DK (1) DK172686A (es)
ES (1) ES8800603A1 (es)
FI (1) FI861691A (es)
NO (1) NO861491L (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5521285A (en) * 1984-01-31 1996-05-28 Akzo Nobel N.V. CTAA 28A32, the antigen recognized by MCA 28A32
US4693975A (en) * 1984-11-20 1987-09-15 The Wistar Institute Human hybridroma fusion partner for production of human monoclonal antibodies
ES8800604A1 (es) * 1985-04-22 1987-11-16 Hybritech Inc Un metodo para producir anticuerpos monoclonales
JP2519038B2 (ja) * 1986-07-29 1996-07-31 郁男 山科 単クロ―ン抗体及びその製造方法
JPH0661276B2 (ja) * 1987-02-24 1994-08-17 ポ−ラ化成工業株式会社 腫瘍関連抗原に特異的な抗体およびこれを利用する抗原の測定法
DK169987D0 (da) * 1987-04-03 1987-04-03 Jens Christian Jensenius Human tumor-associated antigen, ca-ou1
JP2688824B2 (ja) * 1987-05-29 1997-12-10 郁男 山科 単クローン抗体ｎｋｙ１３
US5073493A (en) * 1987-05-29 1991-12-17 Ikuo Yamashina Monoclonal antibody nky13
EP0397419A3 (en) * 1989-05-10 1991-04-03 Hybritech Incorporated Novel tumor-associated antigen, antibodies, compositions and uses therefor
DK0537168T3 (da) * 1990-04-12 1996-09-02 Akzo Nobel Nv Antigenet CTAA 28A32, som genkendes af MCA 28A32
SE9500148D0 (sv) * 1995-01-18 1995-01-18 Bioinvent Internatioal Ab Antibodies for use in cancer therapy and diagnosis
US20050027106A1 (en) * 2003-07-28 2005-02-03 Young David S. F. Cancerous disease modifying antibodies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468457A (en) * 1981-06-01 1984-08-28 David M. Goldenberg Method for producing a CSAp tryptic peptide and anti-CSAp antibodies

Also Published As

Publication number Publication date
EP0199586A2 (en) 1986-10-29
JPS61282096A (ja) 1986-12-12
AU5637086A (en) 1986-10-30
FI861691A (fi) 1986-10-23
EP0199586A3 (en) 1988-05-04
DK172686D0 (da) 1986-04-16
ES554206A0 (es) 1987-11-16
NO861491L (no) 1986-10-23
DK172686A (da) 1986-10-23
FI861691A0 (fi) 1986-04-22

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