ES8800597A1 - Compositions containing 3-aminopropoxy-indoles for treating hypertension - Google Patents
Compositions containing 3-aminopropoxy-indoles for treating hypertensionInfo
- Publication number
- ES8800597A1 ES8800597A1 ES551634A ES551634A ES8800597A1 ES 8800597 A1 ES8800597 A1 ES 8800597A1 ES 551634 A ES551634 A ES 551634A ES 551634 A ES551634 A ES 551634A ES 8800597 A1 ES8800597 A1 ES 8800597A1
- Authority
- ES
- Spain
- Prior art keywords
- aminopropoxy
- indoles
- compositions containing
- treating hypertension
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- VONDEAICGOZHRO-UHFFFAOYSA-N 3-(1h-indol-2-yloxy)propan-1-amine Chemical class C1=CC=C2NC(OCCCN)=CC2=C1 VONDEAICGOZHRO-UHFFFAOYSA-N 0.000 title 1
- 206010020772 Hypertension Diseases 0.000 title 1
- JIVPVXMEBJLZRO-CQSZACIVSA-N 2-chloro-5-[(1r)-1-hydroxy-3-oxo-2h-isoindol-1-yl]benzenesulfonamide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC([C@@]2(O)C3=CC=CC=C3C(=O)N2)=C1 JIVPVXMEBJLZRO-CQSZACIVSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 239000002876 beta blocker Substances 0.000 abstract 1
- 229960001523 chlortalidone Drugs 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229960004569 indapamide Drugs 0.000 abstract 1
- NDDAHWYSQHTHNT-UHFFFAOYSA-N indapamide Chemical compound CC1CC2=CC=CC=C2N1NC(=O)C1=CC=C(Cl)C(S(N)(=O)=O)=C1 NDDAHWYSQHTHNT-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
Abstract
Pharmaceutical compositions contain: < IMAGE > wherein R is hydrogen or benzoyl, in free form or as acid addition salt. They are suitable for the prophylaxis and therapy of ailments normally treated with beta -adrenoceptor blocking agents and are adapted for administration at longer-than-daily intervals. The compositions may further contain a diuretic e.g. chlorthalidone or indapamide etc.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858502887A GB8502887D0 (en) | 1985-02-05 | 1985-02-05 | Pharmaceutical compositions |
| DE3505740 | 1985-02-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8800597A1 true ES8800597A1 (en) | 1987-11-16 |
| ES551634A0 ES551634A0 (en) | 1987-11-16 |
Family
ID=25829545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES551634A Expired ES8800597A1 (en) | 1985-02-05 | 1986-02-04 | Compositions containing 3-aminopropoxy-indoles for treating hypertension |
Country Status (15)
| Country | Link |
|---|---|
| AT (1) | AT393960B (en) |
| AU (1) | AU5293286A (en) |
| BE (1) | BE904146A (en) |
| CH (1) | CH667388A5 (en) |
| DK (1) | DK52186A (en) |
| ES (1) | ES8800597A1 (en) |
| FR (1) | FR2576788A1 (en) |
| GB (1) | GB2173399A (en) |
| GR (1) | GR860307B (en) |
| HU (1) | HU196125B (en) |
| IT (1) | IT1203737B (en) |
| LU (1) | LU86290A1 (en) |
| NL (1) | NL8600137A (en) |
| PH (1) | PH23077A (en) |
| PT (1) | PT81953B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2677886B1 (en) * | 1991-06-18 | 1995-03-31 | Adir | MATRIX TABLET FOR THE EXTENDED RELEASE OF INDAPAMIDE AFTER ORAL ADMINISTRATION. |
| PL193976B1 (en) | 2002-07-01 | 2007-04-30 | Pliva Krakow | Prolonged effect containing indapamide and method of manufacture of prolonged effect tablets containing indapamide |
| DE102004062257A1 (en) | 2004-12-23 | 2006-07-06 | Merckle Gmbh | Directly compressed indapamide sustained-release tablets |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2738568A (en) * | 1953-08-11 | 1956-03-20 | Civitelli Gennaro | Rasp or file |
| AT273761B (en) * | 1965-11-13 | 1969-08-25 | Philipp August Sonn | Puller for ski steel edges |
| GB1260907A (en) * | 1968-06-07 | 1972-01-19 | Sandoz Ltd | Indole derivatives |
| US4139633A (en) * | 1971-06-15 | 1979-02-13 | Ciba-Geigy Corporation | Pharmaceutical preparations for the treatment of hypertonia |
| AT336176B (en) * | 1971-12-10 | 1977-04-25 | Sandoz Ag | METHOD FOR MANUFACTURING A PHARMACEUTICAL PREPARATION |
| GB1425033A (en) * | 1972-03-10 | 1976-02-18 | Hendrickson A E | Data signal recogniion apparatus |
| US3956616A (en) * | 1974-05-06 | 1976-05-11 | Knollenberg Robert G | Method and apparatus for generating a statistical basis |
| DE2635209C2 (en) * | 1975-08-15 | 1983-01-27 | Sandoz-Patent-GmbH, 7850 Lörrach | 4- (2-Benzoyloxy-3-tert-butylamino-propoxy) -2-methylindole, its (S) -enantiomer, their acid addition salts, processes for their preparation and medicaments containing these compounds |
| AT341396B (en) * | 1976-03-01 | 1978-02-10 | C O Oberg & Co Ab | GRINDING DEVICE |
| DE2638716A1 (en) * | 1976-08-27 | 1978-03-02 | Ici Gmbh | ANTIHYPERTENSIVA |
| DE3140432C2 (en) * | 1980-10-13 | 1985-10-10 | Hitachi, Ltd., Tokio/Tokyo | Speed control circuit |
| US4388320A (en) * | 1981-03-09 | 1983-06-14 | Sandoz Ltd. | 3-Aminopropoxyaryl derivative in the treatment of tremor |
| DD205834B1 (en) * | 1982-03-30 | 1985-12-18 | Mansfeld Kombinat W Pieck Veb | QUICK-CHANGE DEVICE FOR TOOLS |
| FR2529785A1 (en) * | 1982-07-09 | 1984-01-13 | Adir | PHARMACEUTICAL COMPOSITION BASED ON INDAPAMIDE AND 8- (3-TERTBUTYLAMINO 2-HYDROXYPROPOXY) THIACHROMAN |
-
1986
- 1986-01-22 HU HU86310A patent/HU196125B/en unknown
- 1986-01-22 NL NL8600137A patent/NL8600137A/en not_active Application Discontinuation
- 1986-01-24 CH CH277/86A patent/CH667388A5/en not_active IP Right Cessation
- 1986-01-30 FR FR8601417A patent/FR2576788A1/en active Pending
- 1986-01-31 BE BE1/011430A patent/BE904146A/en not_active IP Right Cessation
- 1986-02-03 GB GB08602601A patent/GB2173399A/en not_active Withdrawn
- 1986-02-03 DK DK52186A patent/DK52186A/en not_active Application Discontinuation
- 1986-02-03 PT PT81953A patent/PT81953B/en unknown
- 1986-02-03 AU AU52932/86A patent/AU5293286A/en not_active Abandoned
- 1986-02-03 GR GR860307A patent/GR860307B/en unknown
- 1986-02-04 LU LU86290A patent/LU86290A1/en unknown
- 1986-02-04 IT IT47615/86A patent/IT1203737B/en active
- 1986-02-04 PH PH33378A patent/PH23077A/en unknown
- 1986-02-04 AT AT0026186A patent/AT393960B/en not_active IP Right Cessation
- 1986-02-04 ES ES551634A patent/ES8800597A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| HUT44934A (en) | 1988-05-30 |
| HU196125B (en) | 1988-10-28 |
| FR2576788A1 (en) | 1986-08-08 |
| DK52186D0 (en) | 1986-02-03 |
| GB2173399A (en) | 1986-10-15 |
| GB8602601D0 (en) | 1986-03-12 |
| ATA26186A (en) | 1991-07-15 |
| AU5293286A (en) | 1986-08-14 |
| AT393960B (en) | 1992-01-10 |
| PH23077A (en) | 1989-04-10 |
| DK52186A (en) | 1986-08-06 |
| PT81953B (en) | 1987-12-21 |
| IT8647615A0 (en) | 1986-02-04 |
| NL8600137A (en) | 1986-09-01 |
| PT81953A (en) | 1986-03-01 |
| LU86290A1 (en) | 1986-09-02 |
| ES551634A0 (en) | 1987-11-16 |
| GR860307B (en) | 1986-05-27 |
| CH667388A5 (en) | 1988-10-14 |
| BE904146A (en) | 1986-07-31 |
| IT1203737B (en) | 1989-02-23 |
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