ES8800201A1 - Procedimiento para preparar compuestos diarilicos - Google Patents

Procedimiento para preparar compuestos diarilicos

Info

Publication number
ES8800201A1
ES8800201A1 ES554067A ES554067A ES8800201A1 ES 8800201 A1 ES8800201 A1 ES 8800201A1 ES 554067 A ES554067 A ES 554067A ES 554067 A ES554067 A ES 554067A ES 8800201 A1 ES8800201 A1 ES 8800201A1
Authority
ES
Spain
Prior art keywords
alkyl
new
hydro
pyridine
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554067A
Other languages
English (en)
Other versions
ES554067A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of ES554067A0 publication Critical patent/ES554067A0/es
Publication of ES8800201A1 publication Critical patent/ES8800201A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR COMPUESTOS DIARILICOS. CONSISTE EN HACER REACCIONAR A ALDEHIDOS DE FORMULA (II) CON ENAMINAS DE FORMULA (III) Y CON DERIVADOS DE ACIDOS BETA-CETOCARBOXILICOS DE FORMULA (IV), EN DIMETILFORMAMINA, Y ENTRE 20 Y 150GC, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACOLOGICAMENTE ACEPTALBES. SIENDO: (A), ALQUILENO DE C 2 A 5 Y OTROS; AR, UN CICLO DE FORMULA (V); R1, R2 Y R3, H, ALQUILO DE C 1 A 6 Y OTROS; R4 Y R5, H, HIDROXI, HAL Y OTROS; R6, R7, R8 Y R9, H, HIDROXI, ALQUILO DE C 1 A 4 Y OTROS; E Y, O, S O VINILENO. SE UTILIZAN PARA COMBATIR LAS ENFERMEDADES CORONARIAS, ANGINA DE PECHO E INFARTO DE MIOCARDIO. *FORMULA* P
ES554067A 1984-09-28 1986-04-16 Procedimiento para preparar compuestos diarilicos Expired ES8800201A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH465284 1984-09-28

Publications (2)

Publication Number Publication Date
ES554067A0 ES554067A0 (es) 1987-11-01
ES8800201A1 true ES8800201A1 (es) 1987-11-01

Family

ID=4280111

Family Applications (3)

Application Number Title Priority Date Filing Date
ES547385A Expired ES8703148A1 (es) 1984-09-28 1985-09-27 Procedimiento para preparar compuestos diarilicos
ES554068A Expired ES8708135A1 (es) 1984-09-28 1986-04-16 Procedimiento para preparar compuestos diarilicos
ES554067A Expired ES8800201A1 (es) 1984-09-28 1986-04-16 Procedimiento para preparar compuestos diarilicos

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES547385A Expired ES8703148A1 (es) 1984-09-28 1985-09-27 Procedimiento para preparar compuestos diarilicos
ES554068A Expired ES8708135A1 (es) 1984-09-28 1986-04-16 Procedimiento para preparar compuestos diarilicos

Country Status (14)

Country Link
KR (1) KR930001404B1 (es)
AU (1) AU574842B2 (es)
CA (1) CA1291137C (es)
DK (1) DK440885A (es)
ES (3) ES8703148A1 (es)
FI (1) FI83957C (es)
GR (1) GR852364B (es)
HU (1) HU194210B (es)
IE (1) IE66677B1 (es)
IL (1) IL76511A (es)
NO (1) NO169586C (es)
NZ (1) NZ213629A (es)
PT (1) PT81209B (es)
ZA (1) ZA857477B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK704488D0 (da) * 1988-12-19 1988-12-19 Novo Industri As Nye n-substituerede azaheterocykliske carboxylsyrer
DK142287A (da) * 1986-03-27 1987-09-28 Byk Gulden Lomberg Chem Fab Optisk aktive 1,4-dihydropyridinderivater
HU206181B (en) * 1988-02-19 1992-09-28 Byk Gulden Lomberg Chem Fab Process for producing pharmaceutical compositions comprising optically pure r-(+)-niguldipin and its derivatives and suitable for treating tumoros diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK525179A (da) * 1978-12-18 1980-06-19 Sandoz Ag Fremgangsmaade til fremstilling af benzoxadiazoler og benzothiazoler

Also Published As

Publication number Publication date
KR930001404B1 (ko) 1993-02-27
HUT38627A (en) 1986-06-30
FI853415L (fi) 1986-03-29
CA1291137C (en) 1991-10-22
NZ213629A (en) 1989-07-27
IE66677B1 (en) 1996-01-24
ES554068A0 (es) 1987-10-16
ES8703148A1 (es) 1987-02-16
PT81209B (pt) 1988-01-22
NO169586C (no) 1992-07-15
FI83957C (fi) 1991-09-25
AU4794885A (en) 1986-04-10
NO169586B (no) 1992-04-06
DK440885A (da) 1986-03-29
ES8708135A1 (es) 1987-10-16
AU574842B2 (en) 1988-07-14
GR852364B (es) 1985-12-13
ZA857477B (en) 1986-05-28
KR860002497A (ko) 1986-04-26
IE852384L (en) 1986-03-28
ES547385A0 (es) 1987-02-16
HU194210B (en) 1988-01-28
IL76511A (en) 1990-06-10
PT81209A (de) 1985-10-01
FI853415A0 (fi) 1985-09-06
ES554067A0 (es) 1987-11-01
NO853833L (no) 1986-04-01
DK440885D0 (da) 1985-09-27
FI83957B (fi) 1991-06-14

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