ES8800040A1 - Procedimiento para la obtencion de una composicion farmaceutica de liberacion retardada a base de 9,10-dihidro-alcaloides. - Google Patents
Procedimiento para la obtencion de una composicion farmaceutica de liberacion retardada a base de 9,10-dihidro-alcaloides.Info
- Publication number
- ES8800040A1 ES8800040A1 ES551635A ES551635A ES8800040A1 ES 8800040 A1 ES8800040 A1 ES 8800040A1 ES 551635 A ES551635 A ES 551635A ES 551635 A ES551635 A ES 551635A ES 8800040 A1 ES8800040 A1 ES 8800040A1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical
- ergot alkaloid
- containing compositions
- dihydroergotamine
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
PROCEDIMIENTO PARA OBTENER UNA COMPOSICION FARMACEUTICAMENTE DE LIBERACION RETARDADA DE 9,10-HIDRIDRO-ALCALOIDES. COMPRENDE: A) COMBINAR A (A) CON (B), ENTRE 30 Y 90GC Y EN UNA PROPORCION EN PESO DE A/B DE 1:0,5 A 1:10; B) SOLIDIFICAR LA COMBINACION FORMADA; C) ENFRIAR LA COMBINACION SOLIDIFICADA HASTA LA TEMPERATURA AMBIENTE; D) GRANULAR LA COMBINACION ENFRIADA A TEMPERATURA AMBIENTE; E) COMBINAR A LOS GRANULOS DE MASA CON UNA SUSTANCIA (C) EN UNA PORCION EN PESO DE (A+B)/(C) DE 1:4 A 1:50, PARA OBTENER DICHA COMPOSICION FARMACEUTICA. SIENDO: (A), UN 9,10--DIHIDRO-ALCALOIDE; (B), UNA MATERIA GRASA ELEGIDA ENTRE LOS ESTERES DE ACIDOS GRASOS COMO PALMITATO DE CETILO O LOS GLICERIDOS (DIPALMITATO ESTEARATO DE GLICEROL); Y (C), UNA SUSTANCIA HIDROFILA E HINCHABLE TAL COMO HIDROCOLOIDE DE CELULOSA (HIDROXIPROPILMETIL-CELULOSA). SE UTILIZA PARA EL TRATAMIENTO DE ATAQUES DE JAQUECA AGUDA RELACIONADA CON CEFALAGIA VASCULAR. O
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858502889A GB8502889D0 (en) | 1985-02-05 | 1985-02-05 | Co-dergocrine compositions |
| GB858517604A GB8517604D0 (en) | 1985-07-12 | 1985-07-12 | Dihydroergotamine compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES551635A0 ES551635A0 (es) | 1987-10-16 |
| ES8800040A1 true ES8800040A1 (es) | 1987-10-16 |
Family
ID=26288767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES551635A Expired ES8800040A1 (es) | 1985-02-05 | 1986-02-04 | Procedimiento para la obtencion de una composicion farmaceutica de liberacion retardada a base de 9,10-dihidro-alcaloides. |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS61183225A (es) |
| KR (1) | KR920010388B1 (es) |
| AU (1) | AU597570B2 (es) |
| BE (1) | BE904152A (es) |
| CA (1) | CA1263087A (es) |
| CH (1) | CH667592A5 (es) |
| CY (1) | CY1604A (es) |
| DE (1) | DE3602577A1 (es) |
| DK (1) | DK167138B1 (es) |
| ES (1) | ES8800040A1 (es) |
| FR (1) | FR2576787B1 (es) |
| GB (1) | GB2170407B (es) |
| GR (1) | GR860310B (es) |
| HK (1) | HK57191A (es) |
| HU (1) | HU195729B (es) |
| IE (1) | IE59293B1 (es) |
| IT (1) | IT1191255B (es) |
| LU (1) | LU86289A1 (es) |
| NL (1) | NL8600161A (es) |
| NZ (1) | NZ215020A (es) |
| PH (1) | PH23384A (es) |
| PT (1) | PT81954B (es) |
| SE (1) | SE8600496L (es) |
| SG (1) | SG56191G (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2610827B1 (fr) * | 1987-02-18 | 1991-09-13 | Pf Medicament | Comprime de dihydroergotamine (d.h.e.) du type a matrice hydrophile et son procede de fabrication |
| YU47044B (sh) * | 1987-03-11 | 1994-12-28 | LEK TOVARNA FARMACEVTSKIH IN KEMIČNIH IZDELKOV n.sol.o. | Postupak za dobijanje tableta sa produženim delovanjem na bazi hidroksipropil-metilceluloze velike molekularne mase |
| US7771746B2 (en) | 1999-12-03 | 2010-08-10 | Polichem Sa | Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof |
| RU2256454C2 (ru) * | 1999-12-03 | 2005-07-20 | Полишем С.А. | Способы получения фармацевтических композиций алкалоидов спорыньи с пролонгированным действием, характеризующихся улучшенной биодоступностью, и содержащие указанные алкалоиды композиции |
| US20030153620A1 (en) | 2000-05-12 | 2003-08-14 | Meakin Timothy David | Treating eczema and/or psoriasis |
| NZ504526A (en) * | 2000-05-12 | 2003-05-30 | Meracol Corp Ltd | Treating herpes simplex symptoms using a mixture of cetyl myristate and cetyl palmitate |
| WO2001085163A1 (en) * | 2000-05-12 | 2001-11-15 | Meracol Corporation Limited | Treating eczema and/or psoriasis |
| US6696491B2 (en) | 2000-05-12 | 2004-02-24 | Meracol Corporation Limited | Treating irritable bowel syndrome or disease |
| WO2003026640A1 (en) * | 2001-09-28 | 2003-04-03 | Meracol Corporation Limited | Treating food allergies and/or food intolerances |
| CN111297815B (zh) * | 2020-04-29 | 2022-04-15 | 宝利化（南京）制药有限公司 | 一种甲磺酸二氢麦角碱缓释片及其制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3147187A (en) * | 1962-09-10 | 1964-09-01 | Don Hall Lab | Sustained release pharmaceutical |
| CH630257A5 (en) * | 1975-03-17 | 1982-06-15 | Hoffmann La Roche | Sustained release formulation |
| DE3124983A1 (de) * | 1981-06-25 | 1983-01-20 | Meditest Inst Fuer Medizinisch | Arzneiformen zur oralen verabreichung |
| CH649300A5 (de) * | 1981-08-07 | 1985-05-15 | Sandoz Ag | Ergopeptinderivate, ihre herstellung und verwendung. |
| US4369172A (en) * | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
| DE3303616A1 (de) * | 1982-02-12 | 1983-08-25 | Sandoz-Patent-GmbH, 7850 Lörrach | Mutterkornalkaloide, verfahren zu deren herstellung sowie diese verbindungen enthaltende pharmazeutische zubereitungen |
| US4421736A (en) * | 1982-05-20 | 1983-12-20 | Merrel Dow Pharmaceuticals Inc. | Sustained release diethylpropion compositions |
| JPS604120A (ja) * | 1983-06-22 | 1985-01-10 | Shionogi & Co Ltd | 作用持続型ピナシジル製剤 |
| GB2154874B (en) * | 1984-02-29 | 1987-11-04 | Sandoz Ltd | Bromoscriptine compositions |
| GB8413795D0 (en) * | 1984-05-30 | 1984-07-04 | Sandoz Ltd | Organic compounds |
-
1986
- 1986-01-24 NL NL8600161A patent/NL8600161A/nl not_active Application Discontinuation
- 1986-01-24 HU HU86361A patent/HU195729B/hu not_active IP Right Cessation
- 1986-01-27 CH CH296/86A patent/CH667592A5/de not_active IP Right Cessation
- 1986-01-29 DE DE19863602577 patent/DE3602577A1/de not_active Ceased
- 1986-01-31 FR FR868601477A patent/FR2576787B1/fr not_active Expired - Lifetime
- 1986-02-03 DK DK052086A patent/DK167138B1/da not_active IP Right Cessation
- 1986-02-03 IE IE29186A patent/IE59293B1/en not_active IP Right Cessation
- 1986-02-03 BE BE1/011431A patent/BE904152A/fr not_active IP Right Cessation
- 1986-02-03 AU AU52942/86A patent/AU597570B2/en not_active Ceased
- 1986-02-03 GB GB08602602A patent/GB2170407B/en not_active Expired
- 1986-02-03 KR KR1019860000698A patent/KR920010388B1/ko not_active IP Right Cessation
- 1986-02-03 NZ NZ215020A patent/NZ215020A/xx unknown
- 1986-02-03 PT PT81954A patent/PT81954B/pt not_active IP Right Cessation
- 1986-02-03 CA CA000501011A patent/CA1263087A/en not_active Expired
- 1986-02-03 GR GR860310A patent/GR860310B/el unknown
- 1986-02-04 LU LU86289A patent/LU86289A1/fr unknown
- 1986-02-04 SE SE8600496A patent/SE8600496L/ not_active Application Discontinuation
- 1986-02-04 JP JP61023666A patent/JPS61183225A/ja active Pending
- 1986-02-04 ES ES551635A patent/ES8800040A1/es not_active Expired
- 1986-02-04 PH PH33379A patent/PH23384A/en unknown
- 1986-02-05 IT IT47620/86A patent/IT1191255B/it active
-
1991
- 1991-07-16 SG SG561/91A patent/SG56191G/en unknown
- 1991-07-25 HK HK571/91A patent/HK57191A/xx unknown
-
1992
- 1992-04-03 CY CY1604A patent/CY1604A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES551635A0 (es) | 1987-10-16 |
| JPS61183225A (ja) | 1986-08-15 |
| NL8600161A (nl) | 1986-09-01 |
| DK52086A (da) | 1986-08-06 |
| DE3602577A1 (de) | 1986-08-28 |
| CA1263087A (en) | 1989-11-21 |
| PH23384A (en) | 1989-07-26 |
| PT81954A (en) | 1986-03-01 |
| IT8647620A0 (it) | 1986-02-05 |
| SE8600496D0 (sv) | 1986-02-04 |
| SG56191G (en) | 1991-08-23 |
| KR860006265A (ko) | 1986-09-09 |
| HUT41984A (en) | 1987-06-29 |
| IE59293B1 (en) | 1994-02-09 |
| KR920010388B1 (ko) | 1992-11-27 |
| HK57191A (en) | 1991-08-02 |
| CY1604A (en) | 1992-04-03 |
| GB2170407A (en) | 1986-08-06 |
| FR2576787A1 (fr) | 1986-08-08 |
| NZ215020A (en) | 1989-07-27 |
| CH667592A5 (de) | 1988-10-31 |
| GR860310B (en) | 1986-05-27 |
| IT1191255B (it) | 1988-02-24 |
| LU86289A1 (fr) | 1986-09-02 |
| FR2576787B1 (fr) | 1990-01-12 |
| IE860291L (en) | 1986-08-05 |
| DK167138B1 (da) | 1993-09-06 |
| BE904152A (fr) | 1986-08-04 |
| GB2170407B (en) | 1988-10-26 |
| DK52086D0 (da) | 1986-02-03 |
| SE8600496L (sv) | 1986-08-06 |
| AU597570B2 (en) | 1990-06-07 |
| AU5294286A (en) | 1986-08-14 |
| GB8602602D0 (en) | 1986-03-12 |
| PT81954B (pt) | 1988-07-01 |
| HU195729B (en) | 1988-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |