ES8708135A1 - New 1,4-di:hydro-pyridine-3,5 di:carboxylic acid derivs. - Google Patents
New 1,4-di:hydro-pyridine-3,5 di:carboxylic acid derivs.Info
- Publication number
- ES8708135A1 ES8708135A1 ES554068A ES554068A ES8708135A1 ES 8708135 A1 ES8708135 A1 ES 8708135A1 ES 554068 A ES554068 A ES 554068A ES 554068 A ES554068 A ES 554068A ES 8708135 A1 ES8708135 A1 ES 8708135A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- new
- hydro
- pyridine
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1,4-Dihydropyridine derivs. of general formula (I) and their salts are new, where Ar = furyl, thienyl, phenyl, pyridyl, 2,1,3-benzoxadiazolyl or 2,1,3-benzothiadiazolyl, all opt. substd. by 1 or 2 of OH, halogen, NO2, CN, CF3, 1-4C alkyl, 1-4C alkoxy, 1-4C fluoroalkoxy 2-5C alkoxycarbonyl, 2-5C acyl, NH2 and mono- or di(1-4C alkyl)amino R1-R3=H, 1-4C alkyl, 3-7C alkoxyalkyl, aryl, aryl(1-4C)alkyl or aryloxy(1-4C)alkyl Ar1 and Ar2= phenyl opt. substd. by 1 or 2 of OH, halogen, 1-4C alkyl, 1-4C alkoxy, NH2, mono-or di(1-4Calkyl)amino and 1-4C fluoroalkoxy A = 2-5C alkylene opt. substd. by 1-4C alkoxy or aryl.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH465284 | 1984-09-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8708135A1 true ES8708135A1 (en) | 1987-10-16 |
ES554068A0 ES554068A0 (en) | 1987-10-16 |
Family
ID=4280111
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES547385A Expired ES8703148A1 (en) | 1984-09-28 | 1985-09-27 | New 1,4-di:hydro-pyridine-3,5 di:carboxylic acid derivs. |
ES554067A Expired ES8800201A1 (en) | 1984-09-28 | 1986-04-16 | New 1,4-di:hydro-pyridine-3,5 di:carboxylic acid derivs. |
ES554068A Expired ES8708135A1 (en) | 1984-09-28 | 1986-04-16 | New 1,4-di:hydro-pyridine-3,5 di:carboxylic acid derivs. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES547385A Expired ES8703148A1 (en) | 1984-09-28 | 1985-09-27 | New 1,4-di:hydro-pyridine-3,5 di:carboxylic acid derivs. |
ES554067A Expired ES8800201A1 (en) | 1984-09-28 | 1986-04-16 | New 1,4-di:hydro-pyridine-3,5 di:carboxylic acid derivs. |
Country Status (14)
Country | Link |
---|---|
KR (1) | KR930001404B1 (en) |
AU (1) | AU574842B2 (en) |
CA (1) | CA1291137C (en) |
DK (1) | DK440885A (en) |
ES (3) | ES8703148A1 (en) |
FI (1) | FI83957C (en) |
GR (1) | GR852364B (en) |
HU (1) | HU194210B (en) |
IE (1) | IE66677B1 (en) |
IL (1) | IL76511A (en) |
NO (1) | NO169586C (en) |
NZ (1) | NZ213629A (en) |
PT (1) | PT81209B (en) |
ZA (1) | ZA857477B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK704488D0 (en) * | 1988-12-19 | 1988-12-19 | Novo Industri As | NEW N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS |
DK142287A (en) * | 1986-03-27 | 1987-09-28 | Byk Gulden Lomberg Chem Fab | OPTIC ACTIVE 1,4-DIHYDROPYRIDINE DERIVATIVES |
HU206181B (en) * | 1988-02-19 | 1992-09-28 | Byk Gulden Lomberg Chem Fab | Process for producing pharmaceutical compositions comprising optically pure r-(+)-niguldipin and its derivatives and suitable for treating tumoros diseases |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI793848A (en) * | 1978-12-18 | 1980-06-19 | Sandoz Ag | BENZOXADIAZOLER OCH BENZOTHIADIAZOLER DERAS FRAMSTAELLNING OCH PHARMACEUTICAL COMPOSITION INNEHAOLLANDE DESSA |
-
1985
- 1985-09-06 FI FI853415A patent/FI83957C/en not_active IP Right Cessation
- 1985-09-25 HU HU853602A patent/HU194210B/en unknown
- 1985-09-26 KR KR1019850007105A patent/KR930001404B1/en not_active IP Right Cessation
- 1985-09-27 NO NO853833A patent/NO169586C/en unknown
- 1985-09-27 NZ NZ213629A patent/NZ213629A/en unknown
- 1985-09-27 DK DK440885A patent/DK440885A/en not_active Application Discontinuation
- 1985-09-27 GR GR852364A patent/GR852364B/el unknown
- 1985-09-27 CA CA000491694A patent/CA1291137C/en not_active Expired
- 1985-09-27 AU AU47948/85A patent/AU574842B2/en not_active Ceased
- 1985-09-27 ES ES547385A patent/ES8703148A1/en not_active Expired
- 1985-09-27 IE IE238485A patent/IE66677B1/en not_active IP Right Cessation
- 1985-09-27 PT PT81209A patent/PT81209B/en not_active IP Right Cessation
- 1985-09-27 ZA ZA857477A patent/ZA857477B/en unknown
- 1985-09-27 IL IL76511A patent/IL76511A/en not_active IP Right Cessation
-
1986
- 1986-04-16 ES ES554067A patent/ES8800201A1/en not_active Expired
- 1986-04-16 ES ES554068A patent/ES8708135A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES554068A0 (en) | 1987-10-16 |
ZA857477B (en) | 1986-05-28 |
IE66677B1 (en) | 1996-01-24 |
NO169586B (en) | 1992-04-06 |
FI853415L (en) | 1986-03-29 |
FI853415A0 (en) | 1985-09-06 |
NO853833L (en) | 1986-04-01 |
HUT38627A (en) | 1986-06-30 |
PT81209A (en) | 1985-10-01 |
ES547385A0 (en) | 1987-02-16 |
ES8703148A1 (en) | 1987-02-16 |
FI83957B (en) | 1991-06-14 |
IE852384L (en) | 1986-03-28 |
HU194210B (en) | 1988-01-28 |
PT81209B (en) | 1988-01-22 |
IL76511A (en) | 1990-06-10 |
ES8800201A1 (en) | 1987-11-01 |
ES554067A0 (en) | 1987-11-01 |
FI83957C (en) | 1991-09-25 |
AU4794885A (en) | 1986-04-10 |
GR852364B (en) | 1985-12-13 |
AU574842B2 (en) | 1988-07-14 |
KR860002497A (en) | 1986-04-26 |
DK440885D0 (en) | 1985-09-27 |
NZ213629A (en) | 1989-07-27 |
NO169586C (en) | 1992-07-15 |
KR930001404B1 (en) | 1993-02-27 |
DK440885A (en) | 1986-03-29 |
CA1291137C (en) | 1991-10-22 |
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