ES8701990A1 - Procedimiento para la determinacion de la capacidad de fijacion de la globulina fijadora de tiroxina - Google Patents

Procedimiento para la determinacion de la capacidad de fijacion de la globulina fijadora de tiroxina

Info

Publication number
ES8701990A1
ES8701990A1 ES551762A ES551762A ES8701990A1 ES 8701990 A1 ES8701990 A1 ES 8701990A1 ES 551762 A ES551762 A ES 551762A ES 551762 A ES551762 A ES 551762A ES 8701990 A1 ES8701990 A1 ES 8701990A1
Authority
ES
Spain
Prior art keywords
binding
antibody against
enzyme
tbg
thyroxine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551762A
Other languages
English (en)
Other versions
ES551762A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES551762A0 publication Critical patent/ES551762A0/es
Publication of ES8701990A1 publication Critical patent/ES8701990A1/es
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA DETERMINAR LA CAPACIDAD DE FIJACION DE LA G/LOBULINA FIJADORA DE TIROXINA. COMPRENDE: A) INCUBAR LA MUESTRA DE SUERO A INVESTIGAR CON T3 O T4 MARCADA CON ENZIMAS CONOCIDAS COMO LA PEROXIDASA O LA B-GALACTOSIDASA UNIDAS A TRAVES DE UN ESPACIADOR CON UNA LONGITUD DE 3 A 8 ATOMOS DE CARBONO COMO POR EJEMPLO EL ACIDO AMINOBUTIRICO O LA GLICINA; B) INCUBAR CON UN ANTICUERPO CONTRA T4 O TGB INMOVILIZADO CONTRA LA PARTE FC DEL ANTICUERPO, DURANTE MENOS DE 5 MINUTOS EN CASO DE UTILIZARSE ANTICUERPOS ANTI-T4; C) SEPARAR LAS FASES; Y D) MEDIR LA ENZIMA DE MARCACION EN UNA DE LAS FASES. APLICABLE EN MEDICINA, DONDE LA DETERMINACION DE LA CAPACIDAD DE FIJACION DE TGB TIENE IMPORTANCIA ESPECIAL EN EL DIAGNOSTICO DE LA GLANDULA TIROIDES.
ES551762A 1985-02-08 1986-02-07 Procedimiento para la determinacion de la capacidad de fijacion de la globulina fijadora de tiroxina Expired ES8701990A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853504406 DE3504406A1 (de) 1985-02-08 1985-02-08 Verfahren zur bestimmung der bindungskapazitaet des thyroxin bindenden globulins

Publications (2)

Publication Number Publication Date
ES551762A0 ES551762A0 (es) 1986-12-16
ES8701990A1 true ES8701990A1 (es) 1986-12-16

Family

ID=6262061

Family Applications (1)

Application Number Title Priority Date Filing Date
ES551762A Expired ES8701990A1 (es) 1985-02-08 1986-02-07 Procedimiento para la determinacion de la capacidad de fijacion de la globulina fijadora de tiroxina

Country Status (5)

Country Link
EP (1) EP0190765B1 (es)
JP (1) JPS61186855A (es)
AT (1) ATE54373T1 (es)
DE (2) DE3504406A1 (es)
ES (1) ES8701990A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3628795A1 (de) * 1986-08-25 1988-03-03 Hoechst Ag Neue thyroninderivate
US4824777A (en) * 1987-07-08 1989-04-25 Ciba Corning Diagnostics Corp. Method for determining thyroxine uptake
AU618022B2 (en) * 1987-10-02 1991-12-12 Roche Diagnostics Corporation Homogeneous t-4 uptake assay
DE3812610A1 (de) * 1988-04-15 1989-10-26 Boehringer Mannheim Gmbh Verfahren zur bestimmung der thyroxinbindekapazitaet und dazu geeignete standardloesung
CA2131727A1 (en) * 1992-03-30 1993-10-14 Diana E. Clarisse Reagents and methods for the detection and quantification of thyroxine in fluid samples
NL1014927C2 (nl) * 2000-04-12 2001-10-15 Petronella Mariette Meulenberg Werkwijze voor de bepaling van een hormonenverstorende activiteit van milieuverontreinigende stoffen.
JP2007529394A (ja) 2004-03-15 2007-10-25 オーチス エレベータ カンパニー 少なくとも一つの外面が粗面化されたジャケットを有するエレベーターの耐荷重部材

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4040907A (en) * 1974-06-20 1977-08-09 Syva Company Iodothyronine enzyme conjugates
JPS533519A (en) * 1976-06-26 1978-01-13 Nippon Nohyaku Co Ltd Preventives for viral blight of plant
DE2825650C3 (de) * 1978-06-12 1981-02-05 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Bestimmung des Thyroxin-bindungsindex im Serum
US4238471A (en) * 1978-07-12 1980-12-09 Becton, Dickinson And Company Assay for thyroid hormone binding capacity
US4410633A (en) * 1980-09-25 1983-10-18 Corning Glass Works Method for the measurement of free thyroxine or 3,5,3'-triiodothyronine in a liquid sample
US4481298A (en) * 1981-04-13 1984-11-06 Amf Incorporated Pre-precipitated double antibody immunoassay method

Also Published As

Publication number Publication date
JPS61186855A (ja) 1986-08-20
ES551762A0 (es) 1986-12-16
DE3504406A1 (de) 1986-08-14
ATE54373T1 (de) 1990-07-15
EP0190765B1 (de) 1990-07-04
EP0190765A1 (de) 1986-08-13
DE3672356D1 (de) 1990-08-09

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