ES8609233A1 - Procedimiento para preparar compuestos intermedios para ob- tener derivados de los acidos 16-fenoxi y 16-fenoxi susti- tuido-prostatrienoicos - Google Patents

Procedimiento para preparar compuestos intermedios para ob- tener derivados de los acidos 16-fenoxi y 16-fenoxi susti- tuido-prostatrienoicos

Info

Publication number
ES8609233A1
ES8609233A1 ES547691A ES547691A ES8609233A1 ES 8609233 A1 ES8609233 A1 ES 8609233A1 ES 547691 A ES547691 A ES 547691A ES 547691 A ES547691 A ES 547691A ES 8609233 A1 ES8609233 A1 ES 8609233A1
Authority
ES
Spain
Prior art keywords
phenoxy
intermediates
making
acid derivatives
prostatrienoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES547691A
Other languages
English (en)
Other versions
ES547691A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES547691A0 publication Critical patent/ES547691A0/es
Publication of ES8609233A1 publication Critical patent/ES8609233A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE COMPUESTOS DE FORMULA (I) SIENDO R1 Y R2 HIDROGENO O UN GRUPO FORMADOR DE ETER Y X HIDROGENO, HALOGENO, TRIFLUOROMETILO, ALQUILO INFERIOR O ALCOXI INFERIOR. SE PREPARA HACIENDO REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN REACTIVO ACETILURO DE LITIO O ACETILURO DE DICLOROCERIO EN UN DISOLVENTE POLAR BAJO ATMOSFERA INERTE Y DE C80 A C40JC; OPCIONALMENTE SE PUEDE PROTEGER EL GRUPO 1-HIDROXI CUANDO EN LA FORMULA (I) R1 Y R2 SON GRUPOS FORMADORES DE ETER SIENDO EL GRUPO PROTECTOR EL T-BUTILDIMILSILILO; U OPCIONALMENTE SEPARAR LOS GRUPOS PROTECTORES SIENDO R1 Y R2 HIDROGENO. SE UTILIZA PARA LA PREPARACION DE UN COMPIESTO INTERMEDIO UTIL PARA LA PREPARACION DE DERIVADOS DE LOS ACIDOS 16-FENOXI- Y 16-FENOXI SUSTITUIDO-PROSTATRIENOICOS.
ES547691A 1984-10-09 1985-10-08 Procedimiento para preparar compuestos intermedios para ob- tener derivados de los acidos 16-fenoxi y 16-fenoxi susti- tuido-prostatrienoicos Expired ES8609233A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65895084A 1984-10-09 1984-10-09
US77481485A 1985-09-13 1985-09-13

Publications (2)

Publication Number Publication Date
ES547691A0 ES547691A0 (es) 1986-09-01
ES8609233A1 true ES8609233A1 (es) 1986-09-01

Family

ID=27097724

Family Applications (1)

Application Number Title Priority Date Filing Date
ES547691A Expired ES8609233A1 (es) 1984-10-09 1985-10-08 Procedimiento para preparar compuestos intermedios para ob- tener derivados de los acidos 16-fenoxi y 16-fenoxi susti- tuido-prostatrienoicos

Country Status (14)

Country Link
EP (1) EP0177933B1 (es)
KR (1) KR890003941B1 (es)
AT (1) ATE42947T1 (es)
AU (1) AU589911B2 (es)
CA (1) CA1246560A (es)
DE (1) DE3570073D1 (es)
DK (2) DK460585A (es)
ES (1) ES8609233A1 (es)
FI (1) FI853907L (es)
HU (1) HU197290B (es)
IL (1) IL76612A (es)
NO (1) NO163485C (es)
NZ (1) NZ213749A (es)
PL (1) PL146525B1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4600785A (en) * 1983-12-22 1986-07-15 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4912235A (en) * 1983-12-22 1990-03-27 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy- and 16-substituted phenoxy-prostatrienoic acid derivatives and their stereoisomers
US4804787A (en) * 1983-12-22 1989-02-14 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
DE102014018512A1 (de) 2014-12-12 2016-06-16 Giesecke & Devrient Gmbh Optisch variables Sicherheitselement

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES449162A1 (es) * 1975-06-23 1977-12-16 Syntex Inc Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.
DE3107100A1 (de) * 1981-02-20 1982-09-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Azaprostacycline, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
US4600785A (en) * 1983-12-22 1986-07-15 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
NZ212914A (en) * 1984-07-31 1988-08-30 Syntex Inc Tetranorprostaglandin derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
ATE42947T1 (de) 1989-05-15
DK61191D0 (da) 1991-04-05
CA1246560A (en) 1988-12-13
NO853968L (no) 1986-04-10
NO163485C (no) 1990-06-06
KR860003211A (ko) 1986-05-21
DE3570073D1 (en) 1989-06-15
AU589911B2 (en) 1989-10-26
NO163485B (no) 1990-02-26
DK460585D0 (da) 1985-10-08
FI853907A0 (fi) 1985-10-08
AU4840585A (en) 1986-04-17
IL76612A (en) 1990-01-18
EP0177933A3 (en) 1986-09-10
HU197290B (en) 1989-03-28
IL76612A0 (en) 1986-02-28
FI853907L (fi) 1986-04-10
DK61191A (da) 1991-04-05
ES547691A0 (es) 1986-09-01
DK460585A (da) 1986-04-10
KR890003941B1 (ko) 1989-10-13
NZ213749A (en) 1989-01-06
EP0177933B1 (en) 1989-05-10
PL255694A1 (en) 1986-12-02
HUT38612A (en) 1986-06-30
EP0177933A2 (en) 1986-04-16
PL146525B1 (en) 1989-02-28

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506