ES8607968A1 - Un derivado de tetrahidro- -carbolina - Google Patents

Un derivado de tetrahidro- -carbolina

Info

Publication number
ES8607968A1
ES8607968A1 ES537591A ES537591A ES8607968A1 ES 8607968 A1 ES8607968 A1 ES 8607968A1 ES 537591 A ES537591 A ES 537591A ES 537591 A ES537591 A ES 537591A ES 8607968 A1 ES8607968 A1 ES 8607968A1
Authority
ES
Spain
Prior art keywords
lower alkyl
group
phenyl
alkyl
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537591A
Other languages
English (en)
Other versions
ES537591A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of ES537591A0 publication Critical patent/ES537591A0/es
Publication of ES8607968A1 publication Critical patent/ES8607968A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE TETRAHIDRO-B-CARBOLINA Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R1, R2, R3 Y R4 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), CON DISULFURO DE CARBONO EN PRESENCIA O AUSENCIA DE UN COMPUESTO DE FORMULA R41-X1, EN LAS QUE X1 ES UN RESTO REACTIVO, R31 Y R41 PUEDEN SER VARIOS RADICALES Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE EFECTUA EN UN DISOLVENTE INERTE, EN PRESENCIA DE UNA BASE, A UNA TEMPERATURA ENTRE 0JC Y 50JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ENFERMEDADES DEL HIGADO.
ES537591A 1983-11-12 1984-11-12 Un derivado de tetrahidro- -carbolina Expired ES8607968A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838330260A GB8330260D0 (en) 1983-11-12 1983-11-12 Tetrahydro-beta-carboline derivatives

Publications (2)

Publication Number Publication Date
ES537591A0 ES537591A0 (es) 1986-06-01
ES8607968A1 true ES8607968A1 (es) 1986-06-01

Family

ID=10551695

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537591A Expired ES8607968A1 (es) 1983-11-12 1984-11-12 Un derivado de tetrahidro- -carbolina

Country Status (8)

Country Link
US (1) US4628057A (es)
EP (1) EP0145304B1 (es)
JP (1) JPS60120877A (es)
KR (1) KR900007398B1 (es)
CA (1) CA1254210A (es)
DE (1) DE3470541D1 (es)
ES (1) ES8607968A1 (es)
GB (1) GB8330260D0 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100503607C (zh) * 2003-06-02 2009-06-24 新疆华世丹药物研究有限责任公司 去氢骆驼蓬碱衍生物类化合物及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD20923A (es) *
DE20923C (de) * H. LAMPRECHT In Gnarrenburg und G. HlRDES in Bremen Neuerungen an Tropfenzählern
US2187719A (en) * 1938-06-10 1940-01-23 Du Pont Derivative of hexamethylene-di-thio-carbamic acid
ES273769A1 (es) * 1961-01-18 1962-06-01 Geigy Ag J R Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico
US4336260A (en) * 1977-12-08 1982-06-22 The Dow Chemical Company Method and compositions using 1-aryl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid for treating depression

Also Published As

Publication number Publication date
EP0145304A1 (en) 1985-06-19
EP0145304B1 (en) 1988-04-20
CA1254210A (en) 1989-05-16
KR900007398B1 (ko) 1990-10-08
ES537591A0 (es) 1986-06-01
KR850003891A (ko) 1985-06-29
US4628057A (en) 1986-12-09
GB8330260D0 (en) 1983-12-21
JPS60120877A (ja) 1985-06-28
DE3470541D1 (en) 1988-05-26

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960401