ES8605984A1 - Procedimiento para la obtencion de antiflogisticos de depo- sito - Google Patents
Procedimiento para la obtencion de antiflogisticos de depo- sitoInfo
- Publication number
- ES8605984A1 ES8605984A1 ES542317A ES542317A ES8605984A1 ES 8605984 A1 ES8605984 A1 ES 8605984A1 ES 542317 A ES542317 A ES 542317A ES 542317 A ES542317 A ES 542317A ES 8605984 A1 ES8605984 A1 ES 8605984A1
- Authority
- ES
- Spain
- Prior art keywords
- depot
- antiphlogistics
- alcohols
- glycerides
- amides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Inorganic Insulating Materials (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
- Organic Insulating Materials (AREA)
- Medicinal Preparation (AREA)
- Dental Preparations (AREA)
- Reinforced Plastic Materials (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ANTIFLOGISTICOS DE DEPOSITO QUE CONTIENEN N-(A,A,A-TRIFLUOR-M-TOLIL)ANTRANILATO DE 2-(2-HIDROXIETOXI)-ETILO. COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE TRANSESTERIFICA EL ACIDO N-(A,A,A-TRIFLUOR-M-TOLIL)ANTRANILICO EN UN DISOLVENTE ORGANICO INERTE CON UN ALCOHOL DE 1 A 5 ATOMOS DE CARBONO DE BAJO PESO MOLECULAR, CON UN EXCESO DE ALCOHOL Y EN PRESENCIA DE CANTIDADES CATALITICAS DE UN CATALIZADOR ACIDO; SEGUNDA, SE ELIMINA AZEOTROPICAMENTE EL AGUA FORMADA, A UNA TEMPERATURA COMPRENDIDA ENTRE 80 Y 160 GRADOS; TERCERA, EL PRODUCTO OBTENIDO SE TRANSESTERIFICA CON 2-)HIDROXIETOXI)-ETANOL, EN PRESENCIA DE UN CATALIZADOR BASICO; Y POR ULTIMO, EL PRODUCTO RESULTANTE DESPUES DE LA ELIMINACION DEL ALCOHOL DE BAJO PESO MOLECULAR, SE MEZCLA INTENSAMENTE CON UN AGENTE DE SUSPENSION. DE APLICACION EN EL TRATAMIENTO DE PROCESOS INFLAMATORIOS Y DOLOROSOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19833324192 DE3324192A1 (de) | 1983-07-05 | 1983-07-05 | Depot-antiphlogistika |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8605984A1 true ES8605984A1 (es) | 1986-04-16 |
ES542317A0 ES542317A0 (es) | 1986-04-16 |
Family
ID=6203192
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES533848A Expired ES8600932A1 (es) | 1983-07-05 | 1984-06-29 | Procedimiento para la obtencion de antiflogisticos de doposito. |
ES542318A Expired ES8603267A1 (es) | 1983-07-05 | 1985-04-16 | Procedimiento para la obtencion de antiflogisticos de depo- sito |
ES542317A Expired ES8605984A1 (es) | 1983-07-05 | 1985-04-16 | Procedimiento para la obtencion de antiflogisticos de depo- sito |
ES542316A Granted ES542316A0 (es) | 1983-07-05 | 1985-04-16 | Procedimiento para la obtencion de antiflogisticos de depo- sito |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES533848A Expired ES8600932A1 (es) | 1983-07-05 | 1984-06-29 | Procedimiento para la obtencion de antiflogisticos de doposito. |
ES542318A Expired ES8603267A1 (es) | 1983-07-05 | 1985-04-16 | Procedimiento para la obtencion de antiflogisticos de depo- sito |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES542316A Granted ES542316A0 (es) | 1983-07-05 | 1985-04-16 | Procedimiento para la obtencion de antiflogisticos de depo- sito |
Country Status (10)
Country | Link |
---|---|
US (1) | US4594357A (es) |
EP (1) | EP0130524B1 (es) |
JP (1) | JPH0647534B2 (es) |
KR (1) | KR910010019B1 (es) |
AT (1) | ATE45673T1 (es) |
DE (2) | DE3324192A1 (es) |
DK (1) | DK165441C (es) |
ES (4) | ES8600932A1 (es) |
GR (1) | GR82116B (es) |
PT (1) | PT78837B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3446873A1 (de) * | 1984-12-21 | 1986-07-10 | Merckle Gmbh | Fluessige diclofenac-zubereitungen |
DE3726797A1 (de) * | 1987-08-12 | 1989-02-23 | Bayer Ag | Arzneimittel fuer den bereich der mundhoehle |
US5360593A (en) * | 1987-12-29 | 1994-11-01 | Alcon Laboratories, Inc. | Heat sterilization of labile antibiotics |
DE3902079A1 (de) * | 1988-04-15 | 1989-10-26 | Bayer Ag | I.m. injektionsformen von gyrase-inhibitoren |
HU205249B (en) * | 1990-11-09 | 1992-04-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing suspensive aerosole composition |
EP0959873B1 (en) * | 1996-12-20 | 2006-03-01 | ALZA Corporation | Gel composition and methods |
CZ300725B6 (cs) * | 1997-09-30 | 2009-07-29 | Eli Lilly And Company | 2-Methylthienbenzodiazepinová formulace |
DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
ATE511512T1 (de) * | 2005-01-05 | 2011-06-15 | Lilly Co Eli | Olanzapinpamoat-dihydrat |
EP1889198B1 (en) | 2005-04-28 | 2014-11-26 | Proteus Digital Health, Inc. | Pharma-informatics system |
WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
DK3395372T3 (da) | 2009-02-20 | 2022-04-19 | Enhanx Biopharm Inc | System til afgivelse af glutathion-baseret medikament |
EP2427178B1 (en) | 2009-05-06 | 2023-01-04 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3590039A (en) * | 1967-12-20 | 1971-06-29 | Geigy Chem Corp | N - (alpha,alpha,alpha,alpha',alpha',alpha' -hexafluoro - 3,5 - xylyl) anthranilic acid and salts thereof |
US3673243A (en) * | 1968-05-08 | 1972-06-27 | Sumitomo Chemical Co | Novel process for producing o-anilinophenylaliphatic acid derivatives |
US3678094A (en) * | 1970-04-20 | 1972-07-18 | Merck & Co Inc | Substituted anilino carboxylic acids |
JPS474775U (es) * | 1971-02-04 | 1972-09-12 | ||
US3778470A (en) * | 1972-08-23 | 1973-12-11 | A Sallman | Chemical intermediates for the production of substituted 2-anilinophenylacetic acids and esters |
JPS5314606A (en) * | 1976-07-27 | 1978-02-09 | Kawasaki Steel Co | Good hydrogen brittleness resistance line pipe steel |
JPS5337857A (en) * | 1976-09-20 | 1978-04-07 | Matsushita Electric Ind Co Ltd | Composite hybrid integrated circuit |
US4307113A (en) * | 1978-04-20 | 1981-12-22 | Sandoz, Inc. | Anthranilic acid derivatives |
JPS5562049A (en) * | 1978-10-31 | 1980-05-10 | Bago Sa Labor | Novel ester of phenyll and pyridinee33carboxylic acid and its manufacture |
US4325949A (en) * | 1980-02-15 | 1982-04-20 | American Cyanamid Company | Combinations of agents which give enhanced anti-inflammatory activity |
DE3026402A1 (de) * | 1980-07-11 | 1982-02-04 | Syntex Corp., Palo Alto, Calif. | Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen |
JPS5859912A (ja) * | 1981-10-06 | 1983-04-09 | Green Cross Corp:The | 鎮痛消炎物質脂肪乳剤 |
-
1983
- 1983-07-05 DE DE19833324192 patent/DE3324192A1/de not_active Withdrawn
-
1984
- 1984-06-20 US US06/622,425 patent/US4594357A/en not_active Expired - Lifetime
- 1984-06-25 DE DE8484107267T patent/DE3479478D1/de not_active Expired
- 1984-06-25 AT AT84107267T patent/ATE45673T1/de not_active IP Right Cessation
- 1984-06-25 EP EP84107267A patent/EP0130524B1/de not_active Expired
- 1984-06-29 ES ES533848A patent/ES8600932A1/es not_active Expired
- 1984-07-03 PT PT78837A patent/PT78837B/pt not_active IP Right Cessation
- 1984-07-03 GR GR75166A patent/GR82116B/el unknown
- 1984-07-04 DK DK328684A patent/DK165441C/da not_active IP Right Cessation
- 1984-07-04 KR KR1019840003849A patent/KR910010019B1/ko not_active IP Right Cessation
- 1984-07-05 JP JP59138117A patent/JPH0647534B2/ja not_active Expired - Lifetime
-
1985
- 1985-04-16 ES ES542318A patent/ES8603267A1/es not_active Expired
- 1985-04-16 ES ES542317A patent/ES8605984A1/es not_active Expired
- 1985-04-16 ES ES542316A patent/ES542316A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
EP0130524A3 (en) | 1986-08-13 |
PT78837B (en) | 1986-06-02 |
KR850000977A (ko) | 1985-03-14 |
JPH0647534B2 (ja) | 1994-06-22 |
DK165441B (da) | 1992-11-30 |
DK165441C (da) | 1993-04-19 |
US4594357A (en) | 1986-06-10 |
DK328684D0 (da) | 1984-07-04 |
KR910010019B1 (ko) | 1991-12-10 |
GR82116B (es) | 1984-12-13 |
PT78837A (en) | 1984-08-01 |
DE3324192A1 (de) | 1985-01-17 |
ES542318A0 (es) | 1985-12-16 |
ES8603267A1 (es) | 1985-12-16 |
ES533848A0 (es) | 1985-10-16 |
ES8600932A1 (es) | 1985-10-16 |
ES8603266A1 (es) | 1985-12-16 |
ES542317A0 (es) | 1986-04-16 |
DE3479478D1 (en) | 1989-09-28 |
EP0130524B1 (de) | 1989-08-23 |
ATE45673T1 (de) | 1989-09-15 |
DK328684A (da) | 1985-01-06 |
JPS6036408A (ja) | 1985-02-25 |
ES542316A0 (es) | 1985-12-16 |
EP0130524A2 (de) | 1985-01-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8605984A1 (es) | Procedimiento para la obtencion de antiflogisticos de depo- sito | |
UA42795C2 (uk) | Протизапальний засіб для зовнішнього застосування, що містить німесулід, і спосіб його одержання | |
IT1127221B (it) | Composizione a base di magnesio per l'immagazzinamento di idrogeno e procedimento per la preparazione di tale composizione | |
HUT41951A (en) | Process for producing insecticide compositions containing fluorinated ethers as active agents and process for producing the active agents | |
JO1704B1 (en) | New potent compounds | |
MY100883A (en) | The use of salicylic acid esters as perfumes, perfume compositions containing them and new salicylic esters. | |
ES8101530A1 (es) | Un procedimiento para la preparacion de alcoholes beta-gama-dihidro-poliprenilicos. | |
MY101804A (en) | Menthol soap | |
HU9601646D0 (en) | 4-benzoylisoxazoles and their use as herbicides | |
ATE175344T1 (de) | Gelbildende präparate, die optisch angereicherte gelbildner enthalten | |
NZ239813A (en) | Fungicidally active compounds, their methods of production and compositions containing them | |
ES8402269A1 (es) | Procedimiento para preparar 3-acetamido-2-(5-metoxiindol-3-il)propanoato de metilo. | |
HUT33961A (en) | Pesticide compositions containing ester of tricyclohexyl-tinhidroxide and process for producing the active agents | |
EP0034721A3 (en) | Polypeptide and its production and use | |
ES8308832A1 (es) | Procedimiento para preparar derivados fluorados de diaminohepteno o -heptina. | |
CA1274851C (en) | 4-ALKYLPHENYL-2-ALKOXYETHYL ETHERS AND AROMATIC COMPOSITIONS CONTAINING THEM | |
ES8606259A1 (es) | Un metodo de producir una composicion farmaceutica que contiene isoxicamato de l-arginina como ingrediente activo. | |
SU778314A1 (ru) | Литейный сплав на основе алюминия | |
ES1028955U (es) | Auriculares. | |
PH14155A (en) | Pharmaceutical compositions containing racemic or optically active 1-(2',6'-dimethyl-phenoxy)-2-methylaminopropane and method of use | |
AU544307B2 (en) | Varification of recorded messages | |
ES8503321A1 (es) | Procedimiento para desengrasar metales y para limpiar en seco materiales textiles en presencia simultanea de agua. | |
SU952037A1 (ru) | Комплект усиливающих рентгеновских экранов | |
UA16859A1 (uk) | Кріопротектор гемопоетичhих клітиh | |
JPS53112834A (en) | Hydroxybenzoic ester and antiseptic agent containing the same as effective ingredient |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20041004 |