ES8604918A1 - Process for the preparation of a furan derivative - Google Patents

Process for the preparation of a furan derivative

Info

Publication number
ES8604918A1
ES8604918A1 ES547108A ES547108A ES8604918A1 ES 8604918 A1 ES8604918 A1 ES 8604918A1 ES 547108 A ES547108 A ES 547108A ES 547108 A ES547108 A ES 547108A ES 8604918 A1 ES8604918 A1 ES 8604918A1
Authority
ES
Spain
Prior art keywords
methyl
preparation
furan derivative
methylsulphinylmethide
ranitidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES547108A
Other languages
Spanish (es)
Other versions
ES547108A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES8604918A1 publication Critical patent/ES8604918A1/en
Publication of ES547108A0 publication Critical patent/ES547108A0/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Ranitidine is prepared by treating the compound < IMAGE > in which R represents H or preferably methyl with a methylating agent such as a methyl halide, dimethyl sulphate or a methyl sulphonic ester. The reaction may be carried out in the presence of a base or an alkali metal methylsulphinylmethide salt. The starting material (II) is readily obtainable in pure crystalline form and the process does not involve evolution of thiol.
ES547108A 1984-09-20 1985-09-19 Process for the preparation of a furan derivative Expired ES8604918A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848423804A GB8423804D0 (en) 1984-09-20 1984-09-20 Chemical process

Publications (2)

Publication Number Publication Date
ES8604918A1 true ES8604918A1 (en) 1986-02-16
ES547108A0 ES547108A0 (en) 1986-02-16

Family

ID=10567015

Family Applications (1)

Application Number Title Priority Date Filing Date
ES547108A Expired ES8604918A1 (en) 1984-09-20 1985-09-19 Process for the preparation of a furan derivative

Country Status (11)

Country Link
JP (1) JPS61106566A (en)
KR (1) KR870001166B1 (en)
AT (1) AT392639B (en)
CA (1) CA1237440A (en)
DK (1) DK426085A (en)
ES (1) ES8604918A1 (en)
FI (1) FI853599L (en)
GB (2) GB8423804D0 (en)
GR (1) GR852283B (en)
IT (1) IT1200117B (en)
PT (1) PT81161B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
NL8303965A (en) * 1982-12-08 1984-07-02 Degussa NEW FOOD DIAMINE AND GUANIDINE DERIVATIVES; METHOD FOR PREPARING THEREOF MEDICINES CONTAINING THEM; METHOD FOR PREPARING SUCH MEDICINES; APPLICATION OF THE COMPOUNDS FOR THE PREPARATION OF MEDICINAL PRODUCTS AND IN MEDICINE.

Also Published As

Publication number Publication date
FI853599A0 (en) 1985-09-19
GB8523178D0 (en) 1985-10-23
AT392639B (en) 1991-05-10
PT81161A (en) 1985-10-01
CA1237440A (en) 1988-05-31
IT1200117B (en) 1989-01-05
PT81161B (en) 1988-01-22
ES547108A0 (en) 1986-02-16
DK426085D0 (en) 1985-09-19
DK426085A (en) 1986-03-21
IT8548572A0 (en) 1985-09-19
KR860002488A (en) 1986-04-26
GR852283B (en) 1985-12-23
ATA274085A (en) 1990-10-15
KR870001166B1 (en) 1987-06-15
FI853599L (en) 1986-03-21
GB2164647A (en) 1986-03-26
GB8423804D0 (en) 1984-10-24
GB2164647B (en) 1988-02-03
JPS61106566A (en) 1986-05-24

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