ES8604217A1 - Procedimiento para la fabricacion de 5-aza-indol - Google Patents
Procedimiento para la fabricacion de 5-aza-indolInfo
- Publication number
- ES8604217A1 ES8604217A1 ES543461A ES543461A ES8604217A1 ES 8604217 A1 ES8604217 A1 ES 8604217A1 ES 543461 A ES543461 A ES 543461A ES 543461 A ES543461 A ES 543461A ES 8604217 A1 ES8604217 A1 ES 8604217A1
- Authority
- ES
- Spain
- Prior art keywords
- azaindole
- intermediates
- preparation
- pyridine
- dipropylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Design And Manufacture Of Integrated Circuits (AREA)
- Thin Film Transistor (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 5-AZA-INDOL. CONSISTE EN LA REACCION DE CONDENSACION DE 3-METIL-4-NITRO-PIRIDIN-2-OXIDO, CON UN COMPUESTO DE FORMULA (I), EN LA QUE R, R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES, EN AUSENCIA DE DISOLVENTE O EN EL SENO DE UN DISOLVENTE COMO N,N-DIMETILFORMAMIDA, A UNA TEMPERATURA COMPRENDIDA ENTRE 0JC Y 200JC; SEGUIDA DE LA CICLIZACION DE REDUCCION CON HIDROGENO DEL COMPUESTO FORMADO, EN UN DISOLVENTE COMO ETANOL, EN PRESENCIA DE UN CATALIZADOR COMO NIQUEL RANEY O PALADIO SOBRE CARBON A LA TEMPERATURA DE 60JC. ESTE COMPUESTO TIENE APLICACIONES PARA LA SINTESIS DE COMPUESTOS BIOLOGICAMENTE ACTIVOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8408275A FR2564836B1 (fr) | 1984-05-25 | 1984-05-25 | Procede de preparation de l'aza-5 indole et compose obtenu par ce procede |
Publications (2)
Publication Number | Publication Date |
---|---|
ES543461A0 ES543461A0 (es) | 1986-01-16 |
ES8604217A1 true ES8604217A1 (es) | 1986-01-16 |
Family
ID=9304427
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES543461A Expired ES8604217A1 (es) | 1984-05-25 | 1985-05-24 | Procedimiento para la fabricacion de 5-aza-indol |
Country Status (9)
Country | Link |
---|---|
US (1) | US4625033A (es) |
EP (1) | EP0165225B1 (es) |
JP (1) | JPS60258181A (es) |
AT (1) | ATE33138T1 (es) |
CA (1) | CA1259311A (es) |
DE (1) | DE3561947D1 (es) |
ES (1) | ES8604217A1 (es) |
FR (1) | FR2564836B1 (es) |
PT (1) | PT80485B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1321118C (zh) * | 2005-08-02 | 2007-06-13 | 浙江大学 | 5-氮杂吲哚的制备方法 |
CN103980273A (zh) * | 2014-06-03 | 2014-08-13 | 重庆邮电大学 | 5-氮杂吲哚的制备方法 |
CN105646486B (zh) * | 2016-03-01 | 2017-10-13 | 苏州艾缇克药物化学有限公司 | 一种5‑氮杂吲哚的合成方法 |
-
1984
- 1984-05-25 FR FR8408275A patent/FR2564836B1/fr not_active Expired
-
1985
- 1985-05-13 JP JP60102500A patent/JPS60258181A/ja active Pending
- 1985-05-17 PT PT80485A patent/PT80485B/pt not_active IP Right Cessation
- 1985-05-23 EP EP85870072A patent/EP0165225B1/fr not_active Expired
- 1985-05-23 DE DE8585870072T patent/DE3561947D1/de not_active Expired
- 1985-05-23 AT AT85870072T patent/ATE33138T1/de not_active IP Right Cessation
- 1985-05-24 CA CA000482288A patent/CA1259311A/en not_active Expired
- 1985-05-24 ES ES543461A patent/ES8604217A1/es not_active Expired
- 1985-05-28 US US06/738,438 patent/US4625033A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE33138T1 (de) | 1988-04-15 |
FR2564836B1 (fr) | 1986-09-26 |
PT80485B (en) | 1987-04-21 |
EP0165225A1 (fr) | 1985-12-18 |
CA1259311A (en) | 1989-09-12 |
ES543461A0 (es) | 1986-01-16 |
PT80485A (en) | 1985-06-01 |
JPS60258181A (ja) | 1985-12-20 |
FR2564836A1 (fr) | 1985-11-29 |
DE3561947D1 (en) | 1988-04-28 |
EP0165225B1 (fr) | 1988-03-23 |
US4625033A (en) | 1986-11-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970401 |