ES8603189A1 - Procedimiento para la preparacion de derivados de 2-(trial- quil-silil)-ergolina - Google Patents
Procedimiento para la preparacion de derivados de 2-(trial- quil-silil)-ergolinaInfo
- Publication number
- ES8603189A1 ES8603189A1 ES542070A ES542070A ES8603189A1 ES 8603189 A1 ES8603189 A1 ES 8603189A1 ES 542070 A ES542070 A ES 542070A ES 542070 A ES542070 A ES 542070A ES 8603189 A1 ES8603189 A1 ES 8603189A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- bond
- alpha
- formula
- trialkylsilyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 150000003839 salts Chemical class 0.000 abstract 4
- 208000028017 Psychotic disease Diseases 0.000 abstract 2
- 230000001090 anti-dopaminergic effect Effects 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 230000000698 schizophrenic effect Effects 0.000 abstract 2
- -1 alkyl lithium Chemical compound 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
- C07F7/0814—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring is substituted at a C ring atom by Si
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843413660 DE3413660A1 (de) | 1984-04-09 | 1984-04-09 | Verfahren zur herstellung von 2-(trialkyl-silyl)-ergolinderivaten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES542070A0 ES542070A0 (es) | 1985-12-16 |
| ES8603189A1 true ES8603189A1 (es) | 1985-12-16 |
Family
ID=6233293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES542070A Expired ES8603189A1 (es) | 1984-04-09 | 1985-04-09 | Procedimiento para la preparacion de derivados de 2-(trial- quil-silil)-ergolina |
Country Status (3)
| Country | Link |
|---|---|
| CS (1) | CS247100B2 (enrdf_load_stackoverflow) |
| DE (1) | DE3413660A1 (enrdf_load_stackoverflow) |
| ES (1) | ES8603189A1 (enrdf_load_stackoverflow) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6856532B2 (ja) | 2015-01-20 | 2021-04-07 | エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ | エルゴリン化合物およびその使用 |
| CA2974113A1 (en) * | 2015-01-20 | 2016-07-28 | Xoc Pharmaceuticals, Inc. | Isoergoline compounds and uses thereof |
| JP2020522504A (ja) | 2017-06-01 | 2020-07-30 | エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ | 多環式化合物およびそれらの用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3251846A (en) * | 1966-05-17 | G-dimethyosoergolenyl-b | ||
| US3029243A (en) * | 1960-06-20 | 1962-04-10 | Miles Lab | Preparation of dihydroagroclavine from a mixture of agroclavine and elymoclavine |
| CH573937A5 (enrdf_load_stackoverflow) * | 1971-08-05 | 1976-03-31 | Spofa Vereinigte Pharma Werke | |
| US4382940A (en) * | 1979-12-06 | 1983-05-10 | Farmitalia Carlo Erba S.P.A. | Ercoline derivatives and therapeutic compositions having CNS affecting activity |
-
1984
- 1984-04-09 DE DE19843413660 patent/DE3413660A1/de active Granted
-
1985
- 1985-04-04 CS CS252585A patent/CS247100B2/cs unknown
- 1985-04-09 ES ES542070A patent/ES8603189A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3413660A1 (de) | 1985-10-17 |
| ES542070A0 (es) | 1985-12-16 |
| CS247100B2 (en) | 1986-11-13 |
| DE3413660C2 (enrdf_load_stackoverflow) | 1992-03-05 |
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