ES8601698A1 - Procedimiento para producir preparados farmaceuticos a base de heparina y agentes tensioactivos. - Google Patents

Procedimiento para producir preparados farmaceuticos a base de heparina y agentes tensioactivos.

Info

Publication number
ES8601698A1
ES8601698A1 ES533798A ES533798A ES8601698A1 ES 8601698 A1 ES8601698 A1 ES 8601698A1 ES 533798 A ES533798 A ES 533798A ES 533798 A ES533798 A ES 533798A ES 8601698 A1 ES8601698 A1 ES 8601698A1
Authority
ES
Spain
Prior art keywords
surfactants
heparin
throat
nose
mouth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES533798A
Other languages
English (en)
Other versions
ES533798A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intermedicat GmbH
Original Assignee
Intermedicat GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intermedicat GmbH filed Critical Intermedicat GmbH
Publication of ES8601698A1 publication Critical patent/ES8601698A1/es
Publication of ES533798A0 publication Critical patent/ES533798A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

PROCEDIMIENTO PARA PRODUCIR PREPARADOS FARMACEUTICOS A BASE DE HEPARINA Y AGENTES TENSIOACTIVOS. COMPRENDE: INSORPORAR, CON UNA MAQUINA DISPERSADORA DE CORONA DENTADA, UNA MASA FUNDAMENTAL EN AGUA DE 50 A 70C Y DISPERSAR PARA OBTENER UN GEL TRANSPARENTE; AÑADIR, EN PORCIONES, AL GEL TRANSPARENTE UNA SOLUCION ACUOSA QUE CONTIENE HEPARINA, GLICEROL U OTROS, A UNA TEMPERATURA DE 50 A 70C; AÑADIR UN AGENTE TENSIOACTIVO A UNA TEMPERATURA DE 50 A 70C, Y DURANTE UN PERIODO DE TIEMPO DE 30 A 90 MINUTOS; Y ENFRIAR A TEMPERATURA AMBIENTE Y DESGASIFICAR CON APLICACION DE UN VACIO DE 0,1 A 10 TORR.
ES533798A 1983-06-29 1984-06-28 Procedimiento para producir preparados farmaceuticos a base de heparina y agentes tensioactivos. Granted ES533798A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833323389 DE3323389A1 (de) 1983-06-29 1983-06-29 Auf schleimhaeute des mundes, der nase und/oder des rachens wirkende arzneimittel auf der basis von heparin und tensiden

Publications (2)

Publication Number Publication Date
ES8601698A1 true ES8601698A1 (es) 1985-11-01
ES533798A0 ES533798A0 (es) 1985-11-01

Family

ID=6202664

Family Applications (1)

Application Number Title Priority Date Filing Date
ES533798A Granted ES533798A0 (es) 1983-06-29 1984-06-28 Procedimiento para producir preparados farmaceuticos a base de heparina y agentes tensioactivos.

Country Status (6)

Country Link
EP (1) EP0130550A3 (es)
JP (1) JPS6036414A (es)
DE (1) DE3323389A1 (es)
DK (1) DK312184A (es)
ES (1) ES533798A0 (es)
FI (1) FI842588A (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724231A (en) * 1985-04-16 1988-02-09 Nastech Pharmaceutical, Inc. Nasel compositions containing vitamin B12
DE3601132A1 (de) * 1986-01-16 1987-07-23 Christian Bannert Verfahren zur behandlung der schleimhaut
DE3601923A1 (de) * 1986-01-23 1987-07-30 Behringwerke Ag Nasal applizierbares arzneimittel, verfahren zu seiner herstellung und seine verwendung
GB8614189D0 (en) * 1986-06-11 1986-07-16 Leo Pharm Prod Ltd Pharmaceutical composition
NZ222907A (en) * 1986-12-16 1990-08-28 Novo Industri As Preparation for intranasal administration containing a phospholipid absorption enhancing system
US5179079A (en) * 1986-12-16 1993-01-12 Novo Nordisk A/S Nasal formulation and intranasal administration therewith
DK505488D0 (da) * 1987-12-21 1988-09-09 Bar Shalom Daniel Middel og anvendelse af samme
US5916880A (en) * 1987-12-21 1999-06-29 Bukh Meditec A/S Reduction of skin wrinkling using sulphated sugars
FR2645745B1 (fr) * 1989-04-12 1991-09-27 Anben Ste Civile Compositions therapeutiques pour le traitement ou la prevention du ronflement
US5750134A (en) 1989-11-03 1998-05-12 Riker Laboratories, Inc. Bioadhesive composition and patch
AU7681091A (en) * 1990-04-05 1991-10-30 John R Hoidal Method and medicament for prevention or medication of human leucocyte elastase-mediated pulmonary diseases
JPH04305529A (ja) * 1991-03-30 1992-10-28 Kissei Pharmaceut Co Ltd 経鼻投与製剤
IL101056A (en) * 1992-02-24 1997-03-18 Res & Dev Co Ltd Composition for nasal treatment
US5888984A (en) * 1994-05-12 1999-03-30 Dermal Research Laboratories, Inc. Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same
US5639469A (en) * 1994-06-15 1997-06-17 Minnesota Mining And Manufacturing Company Transmucosal delivery system
PT704206E (pt) * 1994-09-30 2003-01-31 Mika Pharma G Fur Die E Und V Composicao farmaceutica
WO1996019198A1 (en) 1994-12-22 1996-06-27 Astra Aktiebolag Aerosol drug formulations
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
ATE361082T1 (de) * 1999-02-01 2007-05-15 Dermal Res Lab Inc Pharmazeutische zusammensetzung aus komplexen kohlenhydraten deren anwendung
US7879824B2 (en) 2001-07-31 2011-02-01 Dermal Research Laboratories, Inc. Methods of preventing or treating diseases and conditions using complex carbohydrates
US7404489B1 (en) 2003-03-04 2008-07-29 Qol Medical, Llc Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
US7229636B1 (en) 2003-03-04 2007-06-12 Nastech Pharmaceutical Company Inc. Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
JP2009504767A (ja) 2005-08-17 2009-02-05 フレミング・アンド・カンパニー・ファーマシューティカルズ ビタミンｂ１２鼻用スプレーおよび使用方法
AR099333A1 (es) * 2014-02-10 2016-07-13 Troikaa Pharmaceuticals Ltd Formulaciones tópicas de heparina

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3500M (fr) * 1964-06-15 1965-08-23 Fo We Forschungs Und Verwertun Nouveau médicament destiné au traitement des rhinites.
US3574832A (en) * 1968-05-29 1971-04-13 American Cyanamid Co Therapeutic heparin-surfactant compositions
US3577534A (en) * 1968-06-20 1971-05-04 Canada Packers Ltd Stable orally active heparinoid complexes
FR2195427A1 (en) * 1972-08-10 1974-03-08 Eurap Sa Heparin compsns. for oral admin. - contg. wetting agent and substance resistant to gastric fluids
GB1381426A (en) * 1973-04-10 1975-01-22 Chugai Pharmaceutical Co Ltd Method of treating mammals and composition comprising oligosaccha ride sulphuric acid esters and nonionic surface active agents
IT1062779B (it) * 1974-04-04 1985-01-14 Crinos Industria Farmaco Composizione farmaceutica contenente un fattore eparinoidico

Also Published As

Publication number Publication date
JPS6036414A (ja) 1985-02-25
FI842588A0 (fi) 1984-06-27
EP0130550A3 (de) 1986-12-30
DE3323389A1 (de) 1985-01-10
FI842588A (fi) 1984-12-30
EP0130550A2 (de) 1985-01-09
DK312184A (da) 1984-12-30
ES533798A0 (es) 1985-11-01
DK312184D0 (da) 1984-06-26

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