ES8507566A1 - Procedimiento para la obtencion de tiazolidinilesteres sustituidos de amidas de acidos minerales - Google Patents
Procedimiento para la obtencion de tiazolidinilesteres sustituidos de amidas de acidos mineralesInfo
- Publication number
- ES8507566A1 ES8507566A1 ES534388A ES534388A ES8507566A1 ES 8507566 A1 ES8507566 A1 ES 8507566A1 ES 534388 A ES534388 A ES 534388A ES 534388 A ES534388 A ES 534388A ES 8507566 A1 ES8507566 A1 ES 8507566A1
- Authority
- ES
- Spain
- Prior art keywords
- lower alkyl
- hydrogen
- independently
- acid amides
- inorganic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000007522 mineralic acids Chemical class 0.000 title 1
- 125000001984 thiazolidinyl group Chemical group 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 239000001257 hydrogen Substances 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 125000002947 alkylene group Chemical group 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 239000005864 Sulphur Substances 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 150000002829 nitrogen Chemical class 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE TIAZOLIDINILESTERES SUSTITUIDOS DE AMIDAS DE ACIDOS MINERALES, DE SUS ISOMEROS PUROS Y DE LAS MEZCLAS DE SUS ISOMEROS, DE FORMULA (I), EN LA QUE X Y R1-R6 PUEDEN SER VARIOS TIPOS DE RADICALES.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO INTRODUCTOR DE ACIDO FOSFORICO DE FORMULE (III), EN LAS QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). O BIEN, EN UN COMPUESTO DE FORMULA (IV), EN LA QUE Z1 Y Z2 SON GRUPOS SUSTITUIBLES, SE SUSTITUYE EL GRUPO Z1 Y/O Z2.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DEL CARCINOMA MAMAL Y DE LA PROSTATA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH394683 | 1983-07-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES534388A0 ES534388A0 (es) | 1985-09-01 |
ES8507566A1 true ES8507566A1 (es) | 1985-09-01 |
Family
ID=4266884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES534388A Expired ES8507566A1 (es) | 1983-07-19 | 1984-07-17 | Procedimiento para la obtencion de tiazolidinilesteres sustituidos de amidas de acidos minerales |
Country Status (20)
Country | Link |
---|---|
US (1) | US4582841A (es) |
EP (1) | EP0132231A3 (es) |
JP (1) | JPS6041688A (es) |
KR (1) | KR850001225A (es) |
AU (1) | AU3082284A (es) |
CA (1) | CA1238327A (es) |
CS (1) | CS241548B2 (es) |
DD (1) | DD219774A5 (es) |
DK (1) | DK351284A (es) |
ES (1) | ES8507566A1 (es) |
FI (1) | FI842854A (es) |
GR (1) | GR79956B (es) |
HU (1) | HU191429B (es) |
IL (1) | IL72434A (es) |
NO (1) | NO158744C (es) |
NZ (1) | NZ208930A (es) |
PL (1) | PL248811A1 (es) |
PT (1) | PT78919B (es) |
RO (1) | RO89010A (es) |
ZA (1) | ZA845539B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5177091A (en) * | 1990-12-06 | 1993-01-05 | Ciba-Geigy Corporation | Use of carbazones as novel active ingredients in medicaments |
AU658175B2 (en) * | 1991-04-12 | 1995-04-06 | Novartis Ag | Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients |
US7477932B2 (en) | 2003-05-28 | 2009-01-13 | Cardiac Pacemakers, Inc. | Cardiac waveform template creation, maintenance and use |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR204619A1 (es) * | 1973-02-13 | 1976-02-20 | Ciba Geigy Ag | Procedimiento para la elaboracion de un nuevo derivado de 2,2-azina-2,4-tiazolidindiona |
ATE18044T1 (de) * | 1982-01-22 | 1986-03-15 | Ciba Geigy Ag | Substituierte thiazolidinylester von mineralsaeuren. |
-
1984
- 1984-07-12 US US06/630,136 patent/US4582841A/en not_active Expired - Fee Related
- 1984-07-13 EP EP84810347A patent/EP0132231A3/de not_active Withdrawn
- 1984-07-16 CS CS845486A patent/CS241548B2/cs unknown
- 1984-07-16 PT PT78919A patent/PT78919B/pt unknown
- 1984-07-16 FI FI842854A patent/FI842854A/fi not_active Application Discontinuation
- 1984-07-17 GR GR75333A patent/GR79956B/el unknown
- 1984-07-17 DD DD84265345A patent/DD219774A5/de unknown
- 1984-07-17 ES ES534388A patent/ES8507566A1/es not_active Expired
- 1984-07-17 RO RO84115266A patent/RO89010A/ro unknown
- 1984-07-17 CA CA000459023A patent/CA1238327A/en not_active Expired
- 1984-07-18 DK DK351284A patent/DK351284A/da not_active Application Discontinuation
- 1984-07-18 JP JP59147728A patent/JPS6041688A/ja active Pending
- 1984-07-18 ZA ZA845539A patent/ZA845539B/xx unknown
- 1984-07-18 KR KR1019840004210A patent/KR850001225A/ko not_active Application Discontinuation
- 1984-07-18 AU AU30822/84A patent/AU3082284A/en not_active Abandoned
- 1984-07-18 HU HU842798A patent/HU191429B/hu unknown
- 1984-07-18 NO NO842937A patent/NO158744C/no unknown
- 1984-07-18 NZ NZ208930A patent/NZ208930A/en unknown
- 1984-07-18 PL PL24881184A patent/PL248811A1/xx unknown
- 1984-07-18 IL IL72434A patent/IL72434A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HU191429B (en) | 1987-02-27 |
ES534388A0 (es) | 1985-09-01 |
FI842854A (fi) | 1985-01-20 |
CS548684A2 (en) | 1985-07-16 |
NZ208930A (en) | 1987-04-30 |
IL72434A0 (en) | 1984-11-30 |
JPS6041688A (ja) | 1985-03-05 |
NO842937L (no) | 1985-01-21 |
IL72434A (en) | 1988-10-31 |
PT78919B (en) | 1986-10-23 |
KR850001225A (ko) | 1985-03-16 |
PL248811A1 (en) | 1985-12-03 |
DK351284A (da) | 1985-01-20 |
FI842854A0 (fi) | 1984-07-16 |
NO158744B (no) | 1988-07-18 |
DK351284D0 (da) | 1984-07-18 |
CS241548B2 (en) | 1986-03-13 |
RO89010A (ro) | 1986-03-30 |
GR79956B (es) | 1984-10-31 |
AU3082284A (en) | 1985-01-24 |
CA1238327A (en) | 1988-06-21 |
EP0132231A2 (de) | 1985-01-23 |
DD219774A5 (de) | 1985-03-13 |
HUT34988A (en) | 1985-05-28 |
US4582841A (en) | 1986-04-15 |
ZA845539B (en) | 1985-02-27 |
EP0132231A3 (de) | 1985-05-22 |
PT78919A (en) | 1984-08-01 |
NO158744C (no) | 1988-10-26 |
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