ES8507114A1 - Procedimiento para la preparacion de derivados de 1, 4-dihidropiridinas - Google Patents

Procedimiento para la preparacion de derivados de 1, 4-dihidropiridinas

Info

Publication number
ES8507114A1
ES8507114A1 ES537427A ES537427A ES8507114A1 ES 8507114 A1 ES8507114 A1 ES 8507114A1 ES 537427 A ES537427 A ES 537427A ES 537427 A ES537427 A ES 537427A ES 8507114 A1 ES8507114 A1 ES 8507114A1
Authority
ES
Spain
Prior art keywords
hydro
formula
pyridine derivs
derivs
toluene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537427A
Other languages
English (en)
Other versions
ES537427A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fordonal SA
Original Assignee
Fordonal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fordonal SA filed Critical Fordonal SA
Priority to ES537427A priority Critical patent/ES8507114A1/es
Publication of ES537427A0 publication Critical patent/ES537427A0/es
Publication of ES8507114A1 publication Critical patent/ES8507114A1/es
Expired legal-status Critical Current

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  • Pyridine Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 1,4-DIHIDROPIRIDINAS.COMPRENDE: A) CONDENSAR UN ALDEHIDO DE FORMULA (II) CON EL ACETOACETATO DE FORMULA (III) Y CON EL 3-AMINOCROTONONITRILO DE FORMULA (IV), EN TETRAHIDROFURANO, DIOXANO O TOLUENO Y A UNA TEMPERATURA ENTRE 15 Y 110JC, PARA OBTENER UN COMPUESTO DE FORMULA (V) Y B) HACER REACCIONAR A (V) CON UN ALCOHOL DE FORMULA (R-OH), EN PRESENCIA DE ACIDO P-TOLUENSULFONICO, SEPARANDO EL DISOLVENTE POR DESTILACION, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SIENDO R UN GRUPO ALQUILO INFERIOR DE C 6.SE UTILIZAN EN CASOS DE HIPERTENSION Y TRASTORNOS VASCULARES CEREBRALES.
ES537427A 1984-11-07 1984-11-07 Procedimiento para la preparacion de derivados de 1, 4-dihidropiridinas Expired ES8507114A1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES537427A ES8507114A1 (es) 1984-11-07 1984-11-07 Procedimiento para la preparacion de derivados de 1, 4-dihidropiridinas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES537427A ES8507114A1 (es) 1984-11-07 1984-11-07 Procedimiento para la preparacion de derivados de 1, 4-dihidropiridinas

Publications (2)

Publication Number Publication Date
ES537427A0 ES537427A0 (es) 1985-09-16
ES8507114A1 true ES8507114A1 (es) 1985-09-16

Family

ID=8488101

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537427A Expired ES8507114A1 (es) 1984-11-07 1984-11-07 Procedimiento para la preparacion de derivados de 1, 4-dihidropiridinas

Country Status (1)

Country Link
ES (1) ES8507114A1 (es)

Also Published As

Publication number Publication date
ES537427A0 (es) 1985-09-16

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20050516