ES8507093A1 - Un procedimiento para la preparacion de derivados de acidos bifenil-alcanoicos - Google Patents

Un procedimiento para la preparacion de derivados de acidos bifenil-alcanoicos

Info

Publication number
ES8507093A1
ES8507093A1 ES537632A ES537632A ES8507093A1 ES 8507093 A1 ES8507093 A1 ES 8507093A1 ES 537632 A ES537632 A ES 537632A ES 537632 A ES537632 A ES 537632A ES 8507093 A1 ES8507093 A1 ES 8507093A1
Authority
ES
Spain
Prior art keywords
biphenylylalkanoic
preparation
methods
pharmaceutical compositions
acid derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537632A
Other languages
English (en)
Other versions
ES537632A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr L Zambeletti SpA
Original Assignee
Dr L Zambeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr L Zambeletti SpA filed Critical Dr L Zambeletti SpA
Publication of ES8507093A1 publication Critical patent/ES8507093A1/es
Publication of ES537632A0 publication Critical patent/ES537632A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/616—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety polycyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE ACIDOS BIFENIL-ALCANOICOS.CONSISTE EN HACER REACCIONAR UN ACIDO BIFENIL-ALCANOICO DE FORMULA (II), CON 2-(2,3-EPOSIPROPOXI)-1-METOXIBENCENO, EN PRESENCIA DE UNA BASE INORGANICA U ORGANICA COMO KOH, NAOH, BIMETILAMINA O TRIETILAMINA, EN ALCOHOLES, CETONAS DIOXANO O TETRAHIDROFURANO, PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO; R, H O ALQUILO DE C 1 A 3 LINEAL O RAMIFICADO; R1 Y R2, H, HAL O HIDROXIDO INSUSTITUIDO O ESTERIFICADO Y R3, H, UN GRUPO ACILO ALIFATICO DE C 1 A 4 LINEAL O RAMIFICADO, AROMATICO DIVERSAMENTE SUSTITUIDO O ARILAFATICO.SE UTILIZAN COMO INHIBIDORES DE LA CICLOOXIGENASIS.
ES537632A 1983-11-28 1984-11-14 Un procedimiento para la preparacion de derivados de acidos bifenil-alcanoicos Granted ES537632A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8323912A IT1212840B (it) 1983-11-28 1983-11-28 Derivati di acidi bifenililalcanoici, loro preparazione e composizioni farmaceutiche che licontengono.

Publications (2)

Publication Number Publication Date
ES8507093A1 true ES8507093A1 (es) 1985-09-16
ES537632A0 ES537632A0 (es) 1985-09-16

Family

ID=11210831

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537632A Granted ES537632A0 (es) 1983-11-28 1984-11-14 Un procedimiento para la preparacion de derivados de acidos bifenil-alcanoicos

Country Status (7)

Country Link
US (1) US4570013A (es)
EP (1) EP0143381B1 (es)
JP (1) JPS60155149A (es)
AT (1) ATE32883T1 (es)
DE (1) DE3469734D1 (es)
ES (1) ES537632A0 (es)
IT (1) IT1212840B (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268008A (en) * 1969-07-09 1972-03-22 Bdh Pharmaceuticals Ltd ESTERS OF p-BYPHENYLYLACETIC ACID
GB1275927A (en) * 1969-07-16 1972-06-01 Bdh Pharmaceuticals Ltd ESTERS OF p-BIPHENYLYLACETIC ACID
FR2514355A1 (fr) * 1981-10-14 1983-04-15 Fabre Sa Pierre Derives de biphenyl alcoyl carboxylates, leur procede de preparation et leur utilisation comme medicaments
IT1190727B (it) * 1982-03-10 1988-02-24 Ausonia Farma Srl Composto ad attivita' analgesica,antiinfiammatoria e mucoregolatrice procedimento per la sua preparazione e relative composizioni farmaceutiche

Also Published As

Publication number Publication date
EP0143381B1 (en) 1988-03-09
ATE32883T1 (de) 1988-03-15
IT8323912A0 (it) 1983-11-28
EP0143381A3 (en) 1986-04-02
ES537632A0 (es) 1985-09-16
US4570013A (en) 1986-02-11
DE3469734D1 (en) 1988-04-14
JPS60155149A (ja) 1985-08-15
IT1212840B (it) 1989-11-30
EP0143381A2 (en) 1985-06-05

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