ES8505177A1 - Procedimiento para la obtencion de un nuevo derivado del acido tiolactico - Google Patents

Procedimiento para la obtencion de un nuevo derivado del acido tiolactico

Info

Publication number
ES8505177A1
ES8505177A1 ES530841A ES530841A ES8505177A1 ES 8505177 A1 ES8505177 A1 ES 8505177A1 ES 530841 A ES530841 A ES 530841A ES 530841 A ES530841 A ES 530841A ES 8505177 A1 ES8505177 A1 ES 8505177A1
Authority
ES
Spain
Prior art keywords
activity
bronchosecretolitic
acid derivative
thiolactic acid
thiolactic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530841A
Other languages
English (en)
Other versions
ES530841A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medea Research SRL
Original Assignee
Medea Research SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medea Research SRL filed Critical Medea Research SRL
Publication of ES530841A0 publication Critical patent/ES530841A0/es
Publication of ES8505177A1 publication Critical patent/ES8505177A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DEL COMPUESTO DE FORMULA (I) Y SUS DIASTEREOISOMEROS Y ENANTIOMEROS.MEDIANTE REACCION DEL CLORHIDRATO DE HOMOCISTEIN-TIOLACTONA CON UN DERIVADO ACTIVADO DEL ACIDO S-TENOIL-TIOLACTICO, EN PRESENCIA DE DISOLVENTES APROTICOS ANHIDROS Y DE ACEPTORES DE LA ACIDEZ, PREFERENTEMENTE AMINAS TERCIARIAS COMO LA TRIETILAMINA. EL DERIVADO ACTIVADO SE OBTIENE PREFERENTEMENTE POR REACCION DEL ACIDO S-TENOIL-TIOLACTICO CON CLOROCARBONATO DE ETILO, A TEMPERATURAS COMPRENDIDAS ENTRE C10JC Y 10JC.DE APLICACION DE ENFERMEDADES DEL SISTEMA RESPIRATORIO Y OTORRINOLARINGOLOGICO.
ES530841A 1983-03-23 1984-03-22 Procedimiento para la obtencion de un nuevo derivado del acido tiolactico Expired ES8505177A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8320236A IT1212723B (it) 1983-03-23 1983-03-23 Derivato dell'acido tiolattico ad attivita'broncosecretogoga.

Publications (2)

Publication Number Publication Date
ES530841A0 ES530841A0 (es) 1985-05-16
ES8505177A1 true ES8505177A1 (es) 1985-05-16

Family

ID=11165014

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530841A Expired ES8505177A1 (es) 1983-03-23 1984-03-22 Procedimiento para la obtencion de un nuevo derivado del acido tiolactico

Country Status (8)

Country Link
US (1) US4481212A (es)
EP (1) EP0120534B1 (es)
JP (1) JPS59186977A (es)
AT (1) ATE25084T1 (es)
DE (2) DE3462137D1 (es)
ES (1) ES8505177A1 (es)
IT (1) IT1212723B (es)
ZA (1) ZA841941B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4867641A (en) * 1986-09-12 1989-09-19 Kabushiki Kaisha Daikin Seisakusho Outer wall structure of a torque converter and others
IT1241415B (it) * 1990-03-05 1994-01-14 Yason Srl Derivato dell'acido s-(2-tenoil)-tiolattico ad attivita' farmacologica
IT1246766B (it) 1990-11-12 1994-11-26 Medea Res Srl N-((2-tenoilmercapto-3-metil)-butanoil)-omocisteina tiolattone, sua preparazione e suo uso come agente terapeutico

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344956A (en) * 1976-04-06 1982-08-17 Nicolo Ercoli Oxotetrahydrothiophenes
CA1121825A (en) * 1978-04-11 1982-04-13 Franco Bolasco 2-(2-thenoylthio)-propionylglycine: method for its preparation and pharmaceutical formulations containing said compound

Also Published As

Publication number Publication date
IT8320236A0 (it) 1983-03-23
EP0120534A1 (en) 1984-10-03
EP0120534B1 (en) 1987-01-21
DE120534T1 (de) 1985-01-17
US4481212A (en) 1984-11-06
IT1212723B (it) 1989-11-30
DE3462137D1 (en) 1987-02-26
ATE25084T1 (de) 1987-02-15
ZA841941B (en) 1984-10-31
JPS642596B2 (es) 1989-01-18
ES530841A0 (es) 1985-05-16
JPS59186977A (ja) 1984-10-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050222