ES8503347A1 - Procedimiento de obtencion de compuestos para la preparacion de agentes inhibidores de la agregacion de plaquetas. - Google Patents
Procedimiento de obtencion de compuestos para la preparacion de agentes inhibidores de la agregacion de plaquetas.Info
- Publication number
- ES8503347A1 ES8503347A1 ES521794A ES521794A ES8503347A1 ES 8503347 A1 ES8503347 A1 ES 8503347A1 ES 521794 A ES521794 A ES 521794A ES 521794 A ES521794 A ES 521794A ES 8503347 A1 ES8503347 A1 ES 8503347A1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- piperidine
- preparation
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS UTILES COMO AGENTES INHIBIDORES DE LA AGREGACION DE PLAQUETAS, EN PARTICULAR PARA PREPARAR COMPUESTOS DE FORMULA (I) Y (II), EN LAS QUE R Y R1 SON HIDROGENO O ALQUILO; Y Z ES UN RADICAL DIAMINICO ORGANICO, Y SUS SALES INCLUIDAS LAS CUATERNARIAS.CONSISTE EN REDUCIR CATALITICAMENTE EL CORRESPONDIENTE COMPUESTO INSATURADO Y EN SU CASO FORMAR LAS SALES CORRESPONDIENTES, FARMACEUTICAMENTE ACEPTABLES, POR REACCION CON HALUROS DE ALQUILO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/368,863 US4443450A (en) | 1982-04-15 | 1982-04-15 | Platelet aggregation inhibitory agents and intermediates therefor |
Publications (2)
Publication Number | Publication Date |
---|---|
ES521794A0 ES521794A0 (es) | 1985-03-01 |
ES8503347A1 true ES8503347A1 (es) | 1985-03-01 |
Family
ID=23453081
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES521794A Expired ES8503347A1 (es) | 1982-04-15 | 1983-04-15 | Procedimiento de obtencion de compuestos para la preparacion de agentes inhibidores de la agregacion de plaquetas. |
ES535122A Expired ES8602762A1 (es) | 1982-04-15 | 1984-08-14 | Metodo de obtener compuestos utiles como agentes inhibidores de la agregacion de plaquetas |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES535122A Expired ES8602762A1 (es) | 1982-04-15 | 1984-08-14 | Metodo de obtener compuestos utiles como agentes inhibidores de la agregacion de plaquetas |
Country Status (12)
Country | Link |
---|---|
US (1) | US4443450A (es) |
EP (1) | EP0096735B1 (es) |
JP (1) | JPS58192869A (es) |
AU (1) | AU556925B2 (es) |
CA (1) | CA1256438A (es) |
DE (1) | DE3380875D1 (es) |
DK (1) | DK163919C (es) |
ES (2) | ES8503347A1 (es) |
GR (1) | GR78182B (es) |
IE (1) | IE55561B1 (es) |
IL (1) | IL68423A (es) |
ZA (1) | ZA832584B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4994462A (en) * | 1982-04-15 | 1991-02-19 | Research Corporation | Platelet aggregation inhibitory agents and intermediate therefor |
US4798830A (en) * | 1982-04-15 | 1989-01-17 | Research Corporation | Platelet aggregation inhibitory agents and intermediates therefor |
AT392783B (de) * | 1987-10-08 | 1991-06-10 | Warner Lambert Co | Neue n-substituierte 3-piperidin- oder 3-tetrahydropyridincarbonsaeuren und derivate |
JPH0623031U (ja) * | 1992-08-25 | 1994-03-25 | 青山眼鏡株式会社 | 眼鏡セット |
US6194413B1 (en) * | 1995-11-13 | 2001-02-27 | Smithkline Beecham Corporation | Hemoregulatory compounds |
CN109824704B (zh) * | 2019-03-15 | 2021-01-15 | 郑州轻工业学院 | 一种基于Evans-Showell型多酸的金属-有机配合物及其制备方法、应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2798070A (en) * | 1954-02-04 | 1957-07-02 | Mcneilab Inc | Quaternary quinoline carboxamide salts and method of preparing same |
NL289475A (es) * | 1962-03-01 | |||
SE431092B (sv) * | 1979-07-10 | 1984-01-16 | Thuresson Af Ekenstam Bo | Terapeutiskt aktiva, substituerade piperidinkarboxianilider |
-
1982
- 1982-04-15 US US06/368,863 patent/US4443450A/en not_active Expired - Fee Related
-
1983
- 1983-04-11 AU AU13411/83A patent/AU556925B2/en not_active Ceased
- 1983-04-12 IE IE825/83A patent/IE55561B1/en not_active IP Right Cessation
- 1983-04-13 GR GR71072A patent/GR78182B/el unknown
- 1983-04-13 ZA ZA832584A patent/ZA832584B/xx unknown
- 1983-04-14 JP JP58066818A patent/JPS58192869A/ja active Granted
- 1983-04-15 EP EP83103664A patent/EP0096735B1/en not_active Expired
- 1983-04-15 IL IL68423A patent/IL68423A/xx unknown
- 1983-04-15 CA CA000425994A patent/CA1256438A/en not_active Expired
- 1983-04-15 DK DK167083A patent/DK163919C/da not_active IP Right Cessation
- 1983-04-15 ES ES521794A patent/ES8503347A1/es not_active Expired
- 1983-04-15 DE DE8383103664T patent/DE3380875D1/de not_active Expired
-
1984
- 1984-08-14 ES ES535122A patent/ES8602762A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE3380875D1 (en) | 1989-12-28 |
ES535122A0 (es) | 1985-12-16 |
DK167083A (da) | 1983-10-16 |
DK163919B (da) | 1992-04-21 |
ES8602762A1 (es) | 1985-12-16 |
IL68423A (en) | 1986-08-31 |
US4443450A (en) | 1984-04-17 |
ZA832584B (en) | 1983-12-28 |
IE830825L (en) | 1983-10-15 |
JPH0530828B2 (es) | 1993-05-11 |
EP0096735B1 (en) | 1989-11-23 |
CA1256438A (en) | 1989-06-27 |
AU1341183A (en) | 1983-10-20 |
ES521794A0 (es) | 1985-03-01 |
DK167083D0 (da) | 1983-04-15 |
DK163919C (da) | 1992-09-21 |
AU556925B2 (en) | 1986-11-27 |
JPS58192869A (ja) | 1983-11-10 |
EP0096735A3 (en) | 1986-08-20 |
GR78182B (es) | 1984-09-26 |
IE55561B1 (en) | 1990-11-07 |
EP0096735A2 (en) | 1983-12-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970401 |