ES8502694A1 - Procedimiento para preparar 1,3,4-benzotriazepinas sustituidas. - Google Patents

Procedimiento para preparar 1,3,4-benzotriazepinas sustituidas.

Info

Publication number
ES8502694A1
ES8502694A1 ES525121A ES525121A ES8502694A1 ES 8502694 A1 ES8502694 A1 ES 8502694A1 ES 525121 A ES525121 A ES 525121A ES 525121 A ES525121 A ES 525121A ES 8502694 A1 ES8502694 A1 ES 8502694A1
Authority
ES
Spain
Prior art keywords
substituted
benzotriazepines
lower alkyl
theire
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES525121A
Other languages
English (en)
Other versions
ES525121A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Publication of ES525121A0 publication Critical patent/ES525121A0/es
Publication of ES8502694A1 publication Critical patent/ES8502694A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/04—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE 1,3,4-BENZOTRIAZEPINAS SUSTITUIDAS, DE FORMULA GENERAL (I), Y SUS SALES DE ADICION DE ACIDOS FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN REACCIONANTE DE FORMULA: R2C-(O-ALCOHIL INFERIOR)3, DISULFURO DE CARBONO O 1,1-CARBONILDIIMIDAZOL.DE APLICACION COMO AGENTES ANTIHIPERTENSIVOS DEBIDO A SU CAPACIDAD PARA REDUCIR LA PRESION SANGUINEA EN MAMIFEROS.
ES525121A 1982-08-26 1983-08-24 Procedimiento para preparar 1,3,4-benzotriazepinas sustituidas. Expired ES8502694A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/412,047 US4482547A (en) 1982-08-26 1982-08-26 Substituted-1,3,4-benzotriazepines

Publications (2)

Publication Number Publication Date
ES525121A0 ES525121A0 (es) 1985-01-16
ES8502694A1 true ES8502694A1 (es) 1985-01-16

Family

ID=23631365

Family Applications (1)

Application Number Title Priority Date Filing Date
ES525121A Expired ES8502694A1 (es) 1982-08-26 1983-08-24 Procedimiento para preparar 1,3,4-benzotriazepinas sustituidas.

Country Status (16)

Country Link
US (1) US4482547A (es)
EP (1) EP0102580B1 (es)
JP (1) JPS5959675A (es)
KR (1) KR840005721A (es)
AT (1) ATE19072T1 (es)
AU (1) AU1844783A (es)
CA (1) CA1227196A (es)
DE (1) DE3362928D1 (es)
DK (1) DK389683A (es)
ES (1) ES8502694A1 (es)
FI (1) FI833025A (es)
GR (1) GR78683B (es)
HU (1) HU188362B (es)
IL (1) IL69560A0 (es)
PT (1) PT77242B (es)
ZA (1) ZA836291B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU212266B (en) * 1992-09-04 1996-04-29 Egyt Gyogyszervegyeszeti Gyar Process for producing novel 1,3,4-benzotriazepin-5(4h)-one derivatives and pharmaceutical preparations containing them
HUE055210T2 (hu) * 2015-02-08 2021-11-29 Alkermes Pharma Ireland Ltd Monometilfumarát prodrug készítmények

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3176008A (en) * 1962-09-11 1965-03-30 American Home Prod 5-phenyl-benzotriazepin-2-one compounds and their production
US4309424A (en) * 1978-10-05 1982-01-05 Hoechst-Roussel Pharmaceuticals Incorporated 4-Phenyl-1,3-benzodiazepines

Also Published As

Publication number Publication date
DK389683A (da) 1984-02-27
KR840005721A (ko) 1984-11-16
EP0102580B1 (en) 1986-04-09
CA1227196A (en) 1987-09-22
DE3362928D1 (en) 1986-05-15
JPS5959675A (ja) 1984-04-05
EP0102580A1 (en) 1984-03-14
IL69560A0 (en) 1983-11-30
FI833025A0 (fi) 1983-08-24
PT77242B (en) 1986-03-18
ZA836291B (en) 1984-04-25
HU188362B (en) 1986-04-28
PT77242A (en) 1983-09-01
DK389683D0 (da) 1983-08-25
FI833025A (fi) 1984-02-27
GR78683B (es) 1984-09-27
US4482547A (en) 1984-11-13
ES525121A0 (es) 1985-01-16
AU1844783A (en) 1984-03-01
ATE19072T1 (de) 1986-04-15

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