ES8501758A1 - Procedimiento para preparar 3-(1h-tetrazol-5-il)-4 (3 h)-quinazolinonas. - Google Patents

Procedimiento para preparar 3-(1h-tetrazol-5-il)-4 (3 h)-quinazolinonas.

Info

Publication number
ES8501758A1
ES8501758A1 ES519005A ES519005A ES8501758A1 ES 8501758 A1 ES8501758 A1 ES 8501758A1 ES 519005 A ES519005 A ES 519005A ES 519005 A ES519005 A ES 519005A ES 8501758 A1 ES8501758 A1 ES 8501758A1
Authority
ES
Spain
Prior art keywords
tetrazol
quinazolinones
appropriate
benzamide
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES519005A
Other languages
English (en)
Other versions
ES519005A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Chemical Co
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of ES519005A0 publication Critical patent/ES519005A0/es
Publication of ES8501758A1 publication Critical patent/ES8501758A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C07D257/06—Five-membered rings with nitrogen atoms directly attached to the ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Adhesive Tapes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Materials For Photolithography (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR 3-(1H-TETRAZOL-5-IL)-4 (3H)-QUINAZOLINONAS, DE FORMULA GENERAL (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN HACER REACCIONAR UNA 2-AMINO BENZAMIDA, DE FORMULA GENERAL (II), CON UN ORTO-ESTER DE FORMULA: R-CO-(C1-4ALQUILO)3, CALENTANDO, OPCIONALMENTE EN PRESENCIA DE UN DISOLVENTE INERTE, PARA OBTENER EL DESEADO TETRAZOL. SI SE TRATA ADECUADAMENTE CON UNA SOLUCION DE UNA BASE APROPIADA SE OBTIENE LA CORRESPONDIENTE SAL FARMACEUTICAMENTE ACEPTABLE.DE APLICACION EN FARMACIA POR SU ACTIVIDAD ANTIALERGICA.
ES519005A 1982-01-18 1983-01-14 Procedimiento para preparar 3-(1h-tetrazol-5-il)-4 (3 h)-quinazolinonas. Expired ES8501758A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/340,577 US4419357A (en) 1982-01-18 1982-01-18 3-(1H-Tetrazol-5-yl)-4(3H)-quinazolinones

Publications (2)

Publication Number Publication Date
ES519005A0 ES519005A0 (es) 1984-12-16
ES8501758A1 true ES8501758A1 (es) 1984-12-16

Family

ID=23333997

Family Applications (1)

Application Number Title Priority Date Filing Date
ES519005A Expired ES8501758A1 (es) 1982-01-18 1983-01-14 Procedimiento para preparar 3-(1h-tetrazol-5-il)-4 (3 h)-quinazolinonas.

Country Status (18)

Country Link
US (1) US4419357A (es)
EP (1) EP0086340B1 (es)
JP (1) JPS58124783A (es)
KR (1) KR880002358B1 (es)
AT (1) ATE18908T1 (es)
AU (2) AU555629B2 (es)
CA (1) CA1254204A (es)
DE (1) DE3362735D1 (es)
DK (1) DK159271C (es)
ES (1) ES8501758A1 (es)
GB (2) GB2113220B (es)
GR (1) GR77393B (es)
IE (1) IE54441B1 (es)
IL (1) IL67686A (es)
NO (1) NO830115L (es)
NZ (1) NZ203034A (es)
PH (1) PH18222A (es)
ZA (1) ZA83240B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4419357A (en) * 1982-01-18 1983-12-06 The Dow Chemical Company 3-(1H-Tetrazol-5-yl)-4(3H)-quinazolinones
US4644065A (en) 1984-05-15 1987-02-17 Merrell Dow Pharmaceuticals Inc. Process for the preparation of 4(3H)-quinazolinones
GB8429739D0 (en) * 1984-11-24 1985-01-03 Fbc Ltd Fungicides
US4761474A (en) * 1986-02-25 1988-08-02 Merrell Dow Pharmaceuticals Inc. 3-(1H-tetrazol-5-yl)thieno[2,3-d]pyrimidin-4(3H)-ones
US4757075A (en) * 1986-10-14 1988-07-12 Merrell Dow Pharmaceuticals Inc. Tetrazolylquinazolinones as anti-hyperuricemic agents
US8975288B2 (en) * 2012-04-10 2015-03-10 The Penn State Research Foundation F2 derivatives as antibacterial agents
EA027847B1 (ru) * 2012-04-27 2017-09-29 Басф Се Замещенные n-(тетразол-5-ил)- и n-(триазол-5-ил)арилкарбоксамидные соединения и их применение в качестве гербицидов

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH364040A (fr) * 1960-04-19 1962-08-31 Ipa Anstalt Dispositif de détection pour vérifier si un élément d'une installation électrique est sous tension
US4035368A (en) * 1975-04-02 1977-07-12 Riker Laboratories, Inc. Substituted 3-(1H-tetrazol-5-yl)-quinoline compounds
GB1561350A (en) * 1976-11-05 1980-02-20 May & Baker Ltd Benzamide derivatives
AU508970B2 (en) * 1976-02-13 1980-04-17 Bristol-Myers Company Tetrazole derivatives
US4122274A (en) * 1977-05-25 1978-10-24 Bristol-Myers Company 3-Tetrazolo-5,6,7,8-substituted-pyrido[1,2-a]pyrimidin-4-ones
US4209620A (en) * 1978-06-19 1980-06-24 Bristol-Myers Company Substituted 3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives having antiallergy activity
NZ192392A (en) * 1978-12-19 1983-02-15 M Ishikawa 3-(substituted (phenyl or pyridyl)) -3,4-dihydroquinazolin-4-ones
GB2095240A (en) * 1981-03-05 1982-09-29 Fujisawa Pharmaceutical Co Dihydropyrimidine derivatives, processes for preparation thereof and pharmaceutical composition comprising the same
US4419357A (en) * 1982-01-18 1983-12-06 The Dow Chemical Company 3-(1H-Tetrazol-5-yl)-4(3H)-quinazolinones

Also Published As

Publication number Publication date
ZA83240B (en) 1983-10-26
JPH0450310B2 (es) 1992-08-13
GB8300957D0 (en) 1983-02-16
IE830078L (en) 1983-07-18
GB2170800A (en) 1986-08-13
AU555629B2 (en) 1986-10-02
DK159271B (da) 1990-09-24
GB8428402D0 (en) 1984-12-19
CA1254204A (en) 1989-05-16
IE54441B1 (en) 1989-10-11
AU6151786A (en) 1986-12-11
GB2113220A (en) 1983-08-03
KR840003250A (ko) 1984-08-20
DE3362735D1 (de) 1986-05-07
EP0086340B1 (en) 1986-04-02
US4419357A (en) 1983-12-06
DK16783A (da) 1983-07-19
DK159271C (da) 1991-02-18
IL67686A0 (en) 1983-05-15
AU1037783A (en) 1983-07-28
NO830115L (no) 1983-07-19
AU570852B2 (en) 1988-03-24
ES519005A0 (es) 1984-12-16
EP0086340A1 (en) 1983-08-24
GB2170800B (en) 1987-01-07
NZ203034A (en) 1985-09-13
KR880002358B1 (ko) 1988-10-29
ATE18908T1 (de) 1986-04-15
GB2113220B (en) 1985-09-04
JPS58124783A (ja) 1983-07-25
PH18222A (en) 1985-04-30
GR77393B (es) 1984-09-11
IL67686A (en) 1985-12-31
DK16783D0 (da) 1983-01-17

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FD1A Patent lapsed

Effective date: 19970519