ES8500741A1 - "procedimiento para la fabricacion de productos farmaceuticos directamente absorbidos por el intestino delgado". - Google Patents

"procedimiento para la fabricacion de productos farmaceuticos directamente absorbidos por el intestino delgado".

Info

Publication number
ES8500741A1
ES8500741A1 ES516399A ES516399A ES8500741A1 ES 8500741 A1 ES8500741 A1 ES 8500741A1 ES 516399 A ES516399 A ES 516399A ES 516399 A ES516399 A ES 516399A ES 8500741 A1 ES8500741 A1 ES 8500741A1
Authority
ES
Spain
Prior art keywords
emulsion
capsule
stomach
pharmaceutical
drug delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516399A
Other languages
English (en)
Other versions
ES516399A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES8500741A1 publication Critical patent/ES8500741A1/es
Publication of ES516399A0 publication Critical patent/ES516399A0/es
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA FABRICACION DE PRODUCTOS FARMACEUTICOS DIRECTAMENTE ABSORBIDOS POR EL INTESTINO DELGADO.COMPRENDE LAS SIGUIENTES FASES: A) FORMACION DE UNA EMULSION CONSTITUIDA POR UN ACEITE QUE POSEE PALMITATO DE VITAMINA A DISUELTO EN EL MISMO, GOMA ARABIGA Y AGUA, SIENDO LA PROPORCION DE GOMA ARABIGA: AGUA:ACEITE, APROXIMADAMENTE 1:2:4; B) HOMOGENEIZACION DE LA EMULSION PARA REDUCIR EL ACEITE A GLOBULOS CON UN DIAMETRO COMPRENDIDO APROXIMADAMENTE ENTRE 500 A Y UNOS 1.000 A Y MEZCLANDO LUEGO LA EMULSION HOMOGENEIZADA CON UNA CANTIDAD DE DEXTRAN EN POLVO EQUIVALENTE APROXIMADAMENTE A 4 VECES EL VOLUMEN DE LA EMULSION; Y C) ENCAPSULAR EN UNA CAPSULA DE GELATINA UNA CANTIDAD DE LA MEZCLA EMULSION-DEXTRAN PARA PROPORCIONAR LA DOSIFICACION UNITARIA DEL PALMITATO DE VITAMINA A.
ES516399A 1981-08-21 1982-08-20 "procedimiento para la fabricacion de productos farmaceuticos directamente absorbidos por el intestino delgado". Granted ES516399A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29490781A 1981-08-21 1981-08-21

Publications (2)

Publication Number Publication Date
ES8500741A1 true ES8500741A1 (es) 1984-11-01
ES516399A0 ES516399A0 (es) 1984-11-01

Family

ID=23135451

Family Applications (1)

Application Number Title Priority Date Filing Date
ES516399A Granted ES516399A0 (es) 1981-08-21 1982-08-20 "procedimiento para la fabricacion de productos farmaceuticos directamente absorbidos por el intestino delgado".

Country Status (11)

Country Link
EP (1) EP0073006B1 (es)
JP (1) JPS5839619A (es)
KR (1) KR840000900A (es)
AR (1) AR231074A1 (es)
AT (1) ATE21212T1 (es)
AU (1) AU557671B2 (es)
CA (1) CA1200492A (es)
DE (1) DE3272452D1 (es)
DK (1) DK373982A (es)
ES (1) ES516399A0 (es)
NO (1) NO822837L (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0212875A3 (en) * 1985-08-12 1988-06-15 William Gough Tucker Medicinal composition and method of making same
KR100560068B1 (ko) * 2002-03-14 2006-03-13 주식회사 태평양 구강용 마이크로 캡슐의 제조방법 및 이 방법에 의해 제조된 마이크로 캡슐을 함유하는 구강용 조성물
JP2005119986A (ja) * 2003-10-15 2005-05-12 Japan Science & Technology Agency 生理活性物質の投与方法、生理活性物質含有乳化液、及び生理活性物質含有乳化液の製造方法
FR3026012B1 (fr) 2014-09-23 2017-12-01 Soc D'exploitation De Produits Pour Les Industries Chimiques Seppic Administration par voie orale d'au moins une substance active pharmaceutique et/ou antigenique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1167794B (de) * 1953-09-03 1964-04-16 Corn Products Company Eine Ges Verfahren zum Einbetten wasserunloeslicher Vitamine und anderer bei der Aufbewahrung sich verschlechternder oder verdampfender Stoffe in eine Umhuellung
DE973095C (de) * 1955-01-19 1959-12-03 Kalle & Co Ag Verfahren zur UEberfuehrung von OElen in streufaehige Pulver durch Spruehtrocknung von OEl-in-Wasser-Emulsionen
GB919193A (en) * 1958-11-12 1963-02-20 Shinshiro Ohtaki A method for producing powder containing oil or fat
US3351531A (en) * 1965-08-09 1967-11-07 Beatrice Foods Co Wheat gluten-encapsulated dried oilin-water dispersions of fat-soluble food, medicaments, flavoring agents or food coloring agents

Also Published As

Publication number Publication date
DE3272452D1 (en) 1986-09-11
AR231074A1 (es) 1984-09-28
ATE21212T1 (de) 1986-08-15
CA1200492A (en) 1986-02-11
JPS5839619A (ja) 1983-03-08
NO822837L (no) 1983-02-22
EP0073006A3 (en) 1983-08-24
ES516399A0 (es) 1984-11-01
DK373982A (da) 1983-02-22
EP0073006B1 (en) 1986-08-06
EP0073006A2 (en) 1983-03-02
KR840000900A (ko) 1984-03-26
AU8706782A (en) 1983-05-12
AU557671B2 (en) 1987-01-08

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