ES8407293A1 - Procedimiento para la preparacion de derivados de piridin-pirimidinona - Google Patents
Procedimiento para la preparacion de derivados de piridin-pirimidinonaInfo
- Publication number
- ES8407293A1 ES8407293A1 ES529415A ES529415A ES8407293A1 ES 8407293 A1 ES8407293 A1 ES 8407293A1 ES 529415 A ES529415 A ES 529415A ES 529415 A ES529415 A ES 529415A ES 8407293 A1 ES8407293 A1 ES 8407293A1
- Authority
- ES
- Spain
- Prior art keywords
- ring
- linear
- pyridine
- compounds
- pyrimidinone derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- WKONRVDUTQPZHA-UHFFFAOYSA-N pyridine;1h-pyrimidin-2-one Chemical class C1=CC=NC=C1.O=C1N=CC=CN1 WKONRVDUTQPZHA-UHFFFAOYSA-N 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical group C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 3
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical group C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical group C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 229930192474 thiophene Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Furan Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE PIRIDIN-PIRIMIDINONA, DE FORMULA GENERAL (I), Y SUS SALES FARMACEUTICAMENTE Y FISIOLOGICAMENTE ACEPTABLES.CONSISTE EN HACER REACCIONAR UNA AMIDINA DE FORMULA GENERAL (II), EN UNA REACCION CATALIZADA POR UNA BASE, CON UN DERIVADO PIRIDINICO DE FORMULA (III).DE APLICACION EN TERAPIA COMO AGENTES ANTIULCEROSOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3306102A DE3306102C1 (de) | 1983-02-22 | 1983-02-22 | Pyridin-Pyrimidinon-Derivate,Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES529415A0 ES529415A0 (es) | 1984-10-01 |
| ES8407293A1 true ES8407293A1 (es) | 1984-10-01 |
Family
ID=6191499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES529415A Expired ES8407293A1 (es) | 1983-02-22 | 1984-02-02 | Procedimiento para la preparacion de derivados de piridin-pirimidinona |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4559344A (es) |
| EP (1) | EP0119510B1 (es) |
| JP (1) | JPS59163385A (es) |
| KR (1) | KR840007595A (es) |
| AT (1) | ATE26713T1 (es) |
| AU (1) | AU562495B2 (es) |
| DE (2) | DE3306102C1 (es) |
| DK (1) | DK42784A (es) |
| ES (1) | ES8407293A1 (es) |
| GR (1) | GR79815B (es) |
| HU (1) | HU192538B (es) |
| IE (1) | IE840386L (es) |
| IL (1) | IL70594A (es) |
| NZ (1) | NZ206853A (es) |
| PT (1) | PT78004B (es) |
| YU (1) | YU254283A (es) |
| ZA (1) | ZA839589B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8411954D0 (en) * | 1984-05-10 | 1984-06-13 | Glaxo Group Ltd | Cephalosporin antibiotics |
| US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1565966A (en) * | 1976-08-04 | 1980-04-23 | Allen & Hanburys Ltd | Aminoalkyl furan derivatives |
| US4521418A (en) * | 1979-02-21 | 1985-06-04 | Smith Kline & French Laboratories Limited | Guanidinothiazolyl derivatives |
| CA1211111A (en) * | 1982-02-15 | 1986-09-09 | Isao Yanagisawa | Process for preparing novel pyrimidone compounds |
| US4808589A (en) * | 1982-02-20 | 1989-02-28 | Smith Kline & French Laboratories Limited | Pyrimidone derivatives |
-
1983
- 1983-02-22 DE DE3306102A patent/DE3306102C1/de not_active Expired
- 1983-12-20 YU YU02542/83A patent/YU254283A/xx unknown
- 1983-12-21 AU AU22723/83A patent/AU562495B2/en not_active Ceased
- 1983-12-27 ZA ZA839589A patent/ZA839589B/xx unknown
-
1984
- 1984-01-01 IL IL70594A patent/IL70594A/xx unknown
- 1984-01-10 GR GR73465A patent/GR79815B/el unknown
- 1984-01-17 NZ NZ206853A patent/NZ206853A/en unknown
- 1984-01-21 KR KR1019840000268A patent/KR840007595A/ko not_active Withdrawn
- 1984-01-25 PT PT78004A patent/PT78004B/pt unknown
- 1984-01-26 US US06/574,077 patent/US4559344A/en not_active Expired - Fee Related
- 1984-01-31 DK DK42784A patent/DK42784A/da not_active Application Discontinuation
- 1984-02-02 ES ES529415A patent/ES8407293A1/es not_active Expired
- 1984-02-20 JP JP59031340A patent/JPS59163385A/ja active Pending
- 1984-02-20 IE IE840386A patent/IE840386L/xx unknown
- 1984-02-20 HU HU84652A patent/HU192538B/hu unknown
- 1984-02-22 DE DE8484101863T patent/DE3463270D1/de not_active Expired
- 1984-02-22 AT AT84101863T patent/ATE26713T1/de not_active IP Right Cessation
- 1984-02-22 EP EP84101863A patent/EP0119510B1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK42784A (da) | 1984-08-23 |
| IL70594A (en) | 1988-06-30 |
| JPS59163385A (ja) | 1984-09-14 |
| YU254283A (en) | 1986-06-30 |
| ATE26713T1 (de) | 1987-05-15 |
| DE3463270D1 (en) | 1987-05-27 |
| DK42784D0 (da) | 1984-01-31 |
| ZA839589B (en) | 1984-09-26 |
| ES529415A0 (es) | 1984-10-01 |
| GR79815B (es) | 1984-10-31 |
| IE840386L (en) | 1984-08-22 |
| US4559344A (en) | 1985-12-17 |
| IL70594A0 (en) | 1984-04-30 |
| PT78004B (de) | 1986-04-10 |
| PT78004A (de) | 1984-02-01 |
| NZ206853A (en) | 1986-03-14 |
| DE3306102C1 (de) | 1984-08-02 |
| KR840007595A (ko) | 1984-12-08 |
| AU562495B2 (en) | 1987-06-11 |
| EP0119510B1 (de) | 1987-04-22 |
| HU192538B (en) | 1987-06-29 |
| AU2272383A (en) | 1984-08-30 |
| EP0119510A1 (de) | 1984-09-26 |
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