ES8404182A1 - Un metodo de prepara el enantiomero (+) s de secoverin - Google Patents

Un metodo de prepara el enantiomero (+) s de secoverin

Info

Publication number
ES8404182A1
ES8404182A1 ES523978A ES523978A ES8404182A1 ES 8404182 A1 ES8404182 A1 ES 8404182A1 ES 523978 A ES523978 A ES 523978A ES 523978 A ES523978 A ES 523978A ES 8404182 A1 ES8404182 A1 ES 8404182A1
Authority
ES
Spain
Prior art keywords
secoverine
enantiomer
active
spasmolytically
spasmolytically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES523978A
Other languages
English (en)
Other versions
ES523978A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duphar International Research BV
Original Assignee
Duphar International Research BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar International Research BV filed Critical Duphar International Research BV
Publication of ES8404182A1 publication Critical patent/ES8404182A1/es
Publication of ES523978A0 publication Critical patent/ES523978A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • External Artificial Organs (AREA)

Abstract

CONSISTE EN LA REACCION DE (B)-1-(4-METOXIFENIL)-1-METILD IETILAMINA, CON UN COMPUESTO DE FORMULA (I), EN LA QUE X ES UN GRUPO ELIMINABLE, E Y ES UN GRUPO CETONICO PROTEGIDO. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, EN PRESENCIA DE UNA BASE, COMO AGENTE FIFADOR DE ACIDO, A UNA TEMPERATURA COMPRENDIDA ENTRE 0JC Y 200JC.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ESPASMOLITICA.
ES523978A 1982-07-12 1983-07-08 Un metodo de prepara el enantiomero (+) s de secoverin Granted ES523978A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8202810A NL8202810A (nl) 1982-07-12 1982-07-12 Spasmolytisch werkzaam (+)-secoverine.

Publications (2)

Publication Number Publication Date
ES8404182A1 true ES8404182A1 (es) 1984-04-16
ES523978A0 ES523978A0 (es) 1984-04-16

Family

ID=19840015

Family Applications (1)

Application Number Title Priority Date Filing Date
ES523978A Granted ES523978A0 (es) 1982-07-12 1983-07-08 Un metodo de prepara el enantiomero (+) s de secoverin

Country Status (13)

Country Link
EP (1) EP0100569B1 (es)
JP (1) JPS5931741A (es)
AT (1) ATE20230T1 (es)
AU (1) AU562820B2 (es)
CA (1) CA1218076A (es)
DE (1) DE3363919D1 (es)
DK (1) DK316783A (es)
ES (1) ES523978A0 (es)
GR (1) GR78645B (es)
IL (1) IL69187A (es)
NL (1) NL8202810A (es)
PH (1) PH22077A (es)
ZA (1) ZA834981B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8700842A (es) * 1987-04-10 1988-11-01 Duphar Int Res
JPH06508836A (ja) * 1991-06-26 1994-10-06 セプラコア，インコーポレーテッド 光学的に純粋なｒ（＋）オンダンセトロンを使用する嘔吐、吐き気および他の障害の治療のための方法および組成物
AU3147593A (en) * 1991-11-26 1993-06-28 Sepracor, Inc. Methods and compositions for treating hypertension, angina and other disorders using optically pure (-) amlodipine
CA2371822A1 (en) 1999-03-01 2000-09-08 Sepracor Inc. Methods for treating apnea and apnea disorders using optically pure r(+)ondansetron

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4125623A (en) * 1974-04-08 1978-11-14 U.S. Philips Corporation Spasmolytics

Also Published As

Publication number Publication date
NL8202810A (nl) 1984-02-01
ATE20230T1 (de) 1986-06-15
ZA834981B (en) 1984-03-28
EP0100569B1 (en) 1986-06-04
EP0100569A1 (en) 1984-02-15
GR78645B (es) 1984-09-27
DE3363919D1 (en) 1986-07-10
AU562820B2 (en) 1987-06-18
DK316783A (da) 1984-01-13
JPS5931741A (ja) 1984-02-20
IL69187A (en) 1986-08-31
AU1663083A (en) 1984-01-19
CA1218076A (en) 1987-02-17
ES523978A0 (es) 1984-04-16
IL69187A0 (en) 1983-11-30
DK316783D0 (da) 1983-07-08
PH22077A (en) 1988-05-20

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203