ES8404179A1 - Procedimiento para la obtencion de un farmaco-deposito implantable y resorbible por el cuerpo a base de fosfato trical- cico. - Google Patents

Procedimiento para la obtencion de un farmaco-deposito implantable y resorbible por el cuerpo a base de fosfato trical- cico.

Info

Publication number
ES8404179A1
ES8404179A1 ES520065A ES520065A ES8404179A1 ES 8404179 A1 ES8404179 A1 ES 8404179A1 ES 520065 A ES520065 A ES 520065A ES 520065 A ES520065 A ES 520065A ES 8404179 A1 ES8404179 A1 ES 8404179A1
Authority
ES
Spain
Prior art keywords
pharmaceuticals
deposition system
pulverulent
sparingly
implanted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES520065A
Other languages
English (en)
Other versions
ES520065A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES520065A0 publication Critical patent/ES520065A0/es
Publication of ES8404179A1 publication Critical patent/ES8404179A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN FARMACO-DEPOSITO IMPLANTABLE Y RESORBIBLE POR EL CUERPO, A BASE DE UN FOSFATO TRICALCICO.CONSISTE EN COMBINAR UN FOSFATO TRICALCICO PULVERULENTO QUE TIENE UN TAMAÑO DE PARTICULA COMPRENDIDO ENTRE 0,5 Y 50 MILIMICRAS, CON UN 0,2 A UN 20 EN PESO DE LA SUSTANCIA ACTIVA Y, EN CASO DADO, CON UN 1 A UN 20 EN PESO DE UN AGLUTINANTE. EL PRODUCTO OBTENIDO SE PRENSA A UNA TEMPERATURA COMPRENDIDA ENTRE LA TEMPERATURA AMBIENTE Y 200 GRADOS Y A UNA PRESION COMPRENDIDA ENTRE 5 Y 1.200 BARES.
ES520065A 1982-02-25 1983-02-24 Procedimiento para la obtencion de un farmaco-deposito implantable y resorbible por el cuerpo a base de fosfato trical- cico. Expired ES8404179A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823206726 DE3206726A1 (de) 1982-02-25 1982-02-25 Pharmakadepot

Publications (2)

Publication Number Publication Date
ES520065A0 ES520065A0 (es) 1984-04-16
ES8404179A1 true ES8404179A1 (es) 1984-04-16

Family

ID=6156637

Family Applications (1)

Application Number Title Priority Date Filing Date
ES520065A Expired ES8404179A1 (es) 1982-02-25 1983-02-24 Procedimiento para la obtencion de un farmaco-deposito implantable y resorbible por el cuerpo a base de fosfato trical- cico.

Country Status (9)

Country Link
EP (1) EP0087662A1 (es)
JP (1) JPS58157715A (es)
AR (1) AR229849A1 (es)
AU (1) AU1024083A (es)
DE (1) DE3206726A1 (es)
DK (1) DK88383A (es)
ES (1) ES8404179A1 (es)
IL (1) IL67974A0 (es)
ZA (1) ZA831223B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3325111A1 (de) * 1983-07-12 1985-01-24 Merck Patent Gmbh, 6100 Darmstadt Implantationsmaterialien
GB8328074D0 (en) * 1983-10-20 1983-11-23 Geistlich Soehne Ag Chemical compositions
NL8401061A (nl) * 1984-04-04 1985-11-01 Stichting Biomaterials Science Werkwijze voor het bereiden van een implantatiemateriaal dat geneesmiddelen afgeeft in het lichaam.
DE3533369A1 (de) * 1985-09-19 1987-03-19 Alois Prof Dr Med Bloemer Antibioticahaltiges mittel und seine verwendung als chirurgisches kunststoffmaterial
DE3729253A1 (de) * 1987-09-02 1989-03-23 Ulrich Dr Mueller Vorrichtung zur verhinderung von infektionen bei aeusseren spannern ("fixateurs externes") in der knochenchirurgie
AP105A (en) * 1987-12-11 1990-11-07 Geo Schwulst Laboratories Ltd Treatment of animals.
DE3810343A1 (de) * 1988-03-26 1989-10-05 Basf Ag Verfahren zur herstellung von festen pharmazeutischen retardformen
EP0376331A3 (en) * 1988-12-29 1991-03-13 Asahi Kogaku Kogyo Kabushiki Kaisha Slow release drug delivery granules and process for production thereof
DE4216496C2 (de) * 1992-05-19 1994-09-22 Werner Prof Dr Med Sattel Verwendung eines Plombenkörpers zum Einsetzen in eine Knochenhöhle, insbesondere in den Markraum eines Röhrenknochens
FR2697184B1 (fr) * 1992-10-28 1994-12-30 Univ Nantes Procédé de fabrication de matériaux, d'intérêt biologique simples ou multiphasés.
DE19521642C2 (de) * 1995-06-14 2000-11-09 Aesculap Ag & Co Kg Implantat, seine Verwendung in der Chirurgie und Verfahren zu seiner Herstellung
DE19527306C1 (de) * 1995-07-26 1997-02-27 Haerle Anton Pharmakafreisetzende Körperchen
DE10113108B4 (de) * 2001-03-15 2007-07-26 Dot Gmbh Wirkstoffhaltige Calciumphosphat-Materialien
IS6389A (is) 2001-08-31 2003-03-03 Heraeus Kulzer Gmbh & Co. Kg Reynsla af sýklalyfjahúðun skrokka, sem í eru örholrými, og einnig af þannig húðuðum skrokkum og notkun þeirra
IS6390A (is) 2001-08-31 2003-03-03 Heraeus Kulzer Gmbh & Co. Kg Reynsla af sýklalyfjahúðun skrokka sem í eru örholrými, þannig húðuðum skrokkum og einnig af notkunþeirra
GB0722484D0 (en) * 2007-11-15 2007-12-27 Ucl Business Plc Solid compositions
DE102012006454A1 (de) 2012-03-30 2013-10-02 Heraeus Medical Gmbh Antiinfektiver Abstandshalter für Osteosyntheseplatten

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2843963A1 (de) * 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
DE2807132C2 (de) * 1978-02-20 1983-11-03 Battelle-Institut E.V., 6000 Frankfurt Implantierbares Pharmaka-Depot
DE2905878A1 (de) * 1979-02-16 1980-08-28 Merck Patent Gmbh Implantationsmaterialien und verfahren zu ihrer herstellung
DK154260C (da) * 1981-02-20 1989-05-22 Mundipharma Gmbh Fremgangsmaade til fremstilling af et knogleimplantat af braendt tricalciumphosphat, specielt til udfyldning af hulrum eller til sammensaetning af knogledele efter fraktur.
EP0061108B1 (de) * 1981-03-19 1986-12-30 mundipharma GmbH Knochenimplantat aus Tricalciumphosphat mit mikro-und makroporöser Struktur, Verfahren zu seiner Herstellung und seiner Verwendung

Also Published As

Publication number Publication date
DK88383A (da) 1983-08-26
AU1024083A (en) 1983-09-01
JPS58157715A (ja) 1983-09-19
ES520065A0 (es) 1984-04-16
DK88383D0 (da) 1983-02-24
AR229849A1 (es) 1983-12-30
DE3206726A1 (de) 1983-09-01
EP0087662A1 (de) 1983-09-07
IL67974A0 (en) 1983-06-15
ZA831223B (en) 1983-11-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991108