ES8403096A1 - Procedimiento para preparar derivados fluorados de alcano diamina, inhibidores de decarboxilasa. - Google Patents

Procedimiento para preparar derivados fluorados de alcano diamina, inhibidores de decarboxilasa.

Info

Publication number
ES8403096A1
ES8403096A1 ES515092A ES515092A ES8403096A1 ES 8403096 A1 ES8403096 A1 ES 8403096A1 ES 515092 A ES515092 A ES 515092A ES 515092 A ES515092 A ES 515092A ES 8403096 A1 ES8403096 A1 ES 8403096A1
Authority
ES
Spain
Prior art keywords
decarboxylase
inhibiting
diamine derivatives
fluorinated alkane
alkane diamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES515092A
Other languages
English (en)
Other versions
ES515092A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merrell Toraude et Cie
Original Assignee
Merrell Toraude et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude et Cie filed Critical Merrell Toraude et Cie
Publication of ES515092A0 publication Critical patent/ES515092A0/es
Publication of ES8403096A1 publication Critical patent/ES8403096A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/09—Diamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS FLUORADOS DE ALCANO DIAMINA, INHIBIDORES DE DECARBOXILASA, DE FORMULA GENERAL (I), EN LA QUE RC REPRESENTA HIDROGENO O CARBOXI; R1 REPRESENTA HIDROGENO O C1 - C6 ALQUILO; Z REPRESENTA METILENO U OXIGENO; M Y N REPRESENTAN 0, 1 O 2; Y P REPRESENTA 1 O 2, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN LA AMINACION DE UN DERIVADO AMINO-PROTEGIDO DEL CORRESPONDIENTE COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R1, M, N Y P TIENEN LOS SIGNIFICADOS YA INDICADOS; R6 REPRESENTA HIDROGENO O CIANO; E Y REPRESENTA UN GRUPO SALIENTE,PARA CONVERTIR EL GRUPO CARBOXI EN UN GRUPO AMINO.DE APLICACION EN EL TRATAMIENTO DE MAMIFEROS PARA EL CONTROL DEL CRECIMIENTO O PROLIFERACION CELULAR INDESEABLE.
ES515092A 1981-08-19 1982-08-18 Procedimiento para preparar derivados fluorados de alcano diamina, inhibidores de decarboxilasa. Expired ES8403096A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8125354 1981-08-19
GB8125361 1981-08-19

Publications (2)

Publication Number Publication Date
ES515092A0 ES515092A0 (es) 1984-03-16
ES8403096A1 true ES8403096A1 (es) 1984-03-16

Family

ID=26280520

Family Applications (1)

Application Number Title Priority Date Filing Date
ES515092A Expired ES8403096A1 (es) 1981-08-19 1982-08-18 Procedimiento para preparar derivados fluorados de alcano diamina, inhibidores de decarboxilasa.

Country Status (14)

Country Link
EP (1) EP0072761B1 (es)
KR (1) KR890001807B1 (es)
AU (1) AU555407B2 (es)
CA (1) CA1204775A (es)
DE (1) DE3268403D1 (es)
DK (1) DK163300C (es)
ES (1) ES8403096A1 (es)
GB (1) GB2104520B (es)
GR (1) GR77602B (es)
IE (1) IE54326B1 (es)
IL (1) IL66570A0 (es)
NO (1) NO153172C (es)
NZ (1) NZ201591A (es)
PH (1) PH17294A (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2847578A1 (fr) * 2002-11-21 2004-05-28 Rhodia Chimie Sa Composes amines porteurs d'au moins un allyle et d'un difluoromethyle et procede utile a leur synthese
FR2838436A1 (fr) * 2002-04-16 2003-10-17 Rhodia Chimie Sa Composes amines porteurs d'au moins un allyle et d'un difluoromethyle et procede utile a leur synthese
JP2005523339A (ja) * 2002-04-16 2005-08-04 ロディア・シミ 少なくともアリル及びジフルオロメチルを有するアミノ化化合物及びそれらの合成に使用される方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2083031B (en) * 1980-08-23 1984-04-18 Merrell Toraude & Co Preparation of aminoacetonitrile derivatives

Also Published As

Publication number Publication date
AU8724582A (en) 1983-02-24
NO153172B (no) 1985-10-21
EP0072761B1 (en) 1986-01-08
PH17294A (en) 1984-07-12
GB2104520A (en) 1983-03-09
IE821943L (en) 1983-02-19
NO822808L (no) 1983-02-21
DK163300C (da) 1992-07-13
IE54326B1 (en) 1989-08-30
KR840001121A (ko) 1984-03-28
DE3268403D1 (de) 1986-02-20
NO153172C (no) 1986-01-29
NZ201591A (en) 1985-07-12
KR890001807B1 (ko) 1989-05-23
CA1204775A (en) 1986-05-20
EP0072761A1 (en) 1983-02-23
GR77602B (es) 1984-09-25
AU555407B2 (en) 1986-09-25
IL66570A0 (en) 1982-12-31
ES515092A0 (es) 1984-03-16
GB2104520B (en) 1985-01-09
DK163300B (da) 1992-02-17
DK370982A (da) 1983-02-20

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401