ES8400435A1 - Procedimiento para preparar 1,2-dihidropirido (3,4 6) pirazinas. - Google Patents

Procedimiento para preparar 1,2-dihidropirido (3,4 6) pirazinas.

Info

Publication number
ES8400435A1
ES8400435A1 ES515559A ES515559A ES8400435A1 ES 8400435 A1 ES8400435 A1 ES 8400435A1 ES 515559 A ES515559 A ES 515559A ES 515559 A ES515559 A ES 515559A ES 8400435 A1 ES8400435 A1 ES 8400435A1
Authority
ES
Spain
Prior art keywords
dihydropyrido
pyrazines
novel
preparing same
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES515559A
Other languages
English (en)
Other versions
ES515559A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Southern Research Institute
Original Assignee
Southern Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/354,164 external-priority patent/US4450160A/en
Application filed by Southern Research Institute filed Critical Southern Research Institute
Publication of ES8400435A1 publication Critical patent/ES8400435A1/es
Publication of ES515559A0 publication Critical patent/ES515559A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA PREPARAR 1,2-DIHIDROPIRIDO (3,4-B) PIRAZINAS.SE SOMETE A AMINACION INFERIOR A UN 6-AMINO-4CLORO-5-NITROPIRIDIN-2-ILCARBAMATO CON UN ALFA-AMINOALCOHOL (II) PARA DAR UN COMPUESTO (III), AL CUAL SE OXIDA PARA DAR UNA CETONA, LA CUAL SE SOMETE A HIDROGENACION CATALITICA. SE OBTIENE (I) DONDE X ES 1, 2 O 3; R1 ES UN ALCOHILO INFERIOR; R2 ES HIDROGENO, RADICALES ALCOHILO, ALQUENILO, CICLOALCOHILO, ARALCOHILO O ALCARILO; R3 Y R4 SON AMBOS HIDROGENO O UNO DE ELLOS ES HIDROGENO U EL OTRO UN GRUPO ALCOHILO INFERIOR.
ES515559A 1981-03-24 1982-09-08 Procedimiento para preparar 1,2-dihidropirido (3,4 6) pirazinas. Granted ES515559A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24715881A 1981-03-24 1981-03-24
US06/354,164 US4450160A (en) 1981-12-07 1982-03-03 1,2-Dihydropyrido[3,4-b]-pyrazines and method and intermediates for preparing same

Publications (2)

Publication Number Publication Date
ES8400435A1 true ES8400435A1 (es) 1983-10-16
ES515559A0 ES515559A0 (es) 1983-10-16

Family

ID=26938495

Family Applications (2)

Application Number Title Priority Date Filing Date
ES515559A Granted ES515559A0 (es) 1981-03-24 1982-09-08 Procedimiento para preparar 1,2-dihidropirido (3,4 6) pirazinas.
ES515558A Expired ES8400434A1 (es) 1981-03-24 1982-09-08 "un procedimiento para preparar 1,2-dihidropirido(3,4-b)pirazinas".

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES515558A Expired ES8400434A1 (es) 1981-03-24 1982-09-08 "un procedimiento para preparar 1,2-dihidropirido(3,4-b)pirazinas".

Country Status (9)

Country Link
EP (2) EP0061178B1 (es)
JP (3) JPH01279863A (es)
AU (1) AU547435B2 (es)
CA (1) CA1198111A (es)
DE (1) DE3269284D1 (es)
DK (1) DK164160C (es)
ES (2) ES515559A0 (es)
FI (1) FI75567C (es)
NO (1) NO156942C (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4600716A (en) * 1982-03-26 1986-07-15 Southern Research Institute 1,2-dihydropyrido[3,4-b]pyrazines
US4866059A (en) * 1988-04-04 1989-09-12 Warner-Lambert Company '(2S)-(5-amino-1,2-dihydro-2-methyl-3-phenylpyrido(3,4-b)pyrazin-7-yl)-carbamic acid, ethyl ester
US6388076B1 (en) * 1995-06-19 2002-05-14 Ontogen Corporation Protein tyrosine phosphatase-inhibiting compounds
JP4380847B2 (ja) 1999-07-21 2009-12-09 東京自動機工株式会社 伝動機の伝達体加圧制御装置

Also Published As

Publication number Publication date
ES515558A0 (es) 1983-10-16
EP0061178B1 (en) 1986-02-26
NO156942C (no) 1987-12-23
JPH01279864A (ja) 1989-11-10
JPH0428697B2 (es) 1992-05-15
AU547435B2 (en) 1985-10-17
DE3269284D1 (en) 1986-04-03
NO820953L (no) 1982-09-27
ES8400434A1 (es) 1983-10-16
EP0151765A3 (en) 1985-09-18
AU8182282A (en) 1982-09-30
EP0061178A3 (en) 1982-12-01
JPH0428263B2 (es) 1992-05-13
ES515559A0 (es) 1983-10-16
JPH0427234B2 (es) 1992-05-11
FI75567B (fi) 1988-03-31
JPH01279865A (ja) 1989-11-10
EP0061178A2 (en) 1982-09-29
NO156942B (no) 1987-09-14
DK164160B (da) 1992-05-18
FI75567C (fi) 1988-07-11
DK133782A (da) 1982-09-25
EP0151765B1 (en) 1987-07-08
FI820982L (fi) 1982-09-25
CA1198111A (en) 1985-12-17
EP0151765A2 (en) 1985-08-21
DK164160C (da) 1992-11-02
JPH01279863A (ja) 1989-11-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303