ES8308890A1 - Procedimiento para la preparacion de cetales de 3'-deshidro -cardenolido-tridigitoxosidos. - Google Patents

Procedimiento para la preparacion de cetales de 3'-deshidro -cardenolido-tridigitoxosidos.

Info

Publication number
ES8308890A1
ES8308890A1 ES517673A ES517673A ES8308890A1 ES 8308890 A1 ES8308890 A1 ES 8308890A1 ES 517673 A ES517673 A ES 517673A ES 517673 A ES517673 A ES 517673A ES 8308890 A1 ES8308890 A1 ES 8308890A1
Authority
ES
Spain
Prior art keywords
ketals
image
tridigitoxosides
preparation
cardenolide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES517673A
Other languages
English (en)
Other versions
ES517673A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES8308890A1 publication Critical patent/ES8308890A1/es
Publication of ES517673A0 publication Critical patent/ES517673A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J19/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
    • C07J19/005Glycosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Processing Of Color Television Signals (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE CETALES DE 3 -DESHIDRO-CARDENOLIDO-TRIDIGITOXOSIDOS, DE FORMULA GENERAL (I), EN LA QUE R<1 Y R<2 REPRESENTAN GRUPOS ALCOHILOS O UN CETAL CICLICO; R<3 REPRESENTA HIDROGENO; Y R<4 REPRESENTA HIDROGENO O UN GRUPO ACILO O ALCOHILO INFERIOR. CONSISTE EN HACER REACCIONAR COMPUESTOS DE FORMULA (II), EN LA QUE R<3 SIGNIFICA HIDROGENO O UN ATOMO DE OXIGENO; Y R<4 SIGNIFICA HIDROGENO O UN GRUPO ACILO O ALCOHILO INFERIOR, CON ALCANOLES MONOVALENTES CON 1 A 3 ATOMOS DE CARBONO O CON ALCANOLES DIVALENTES CON 2 A 6 ATOMOS DE CARBONO. DE APLICACION EN LA PREPARACION DE MEDICAMENTOS CONTRA LA INSUFICIENCIA CARDIACA.
ES517673A 1981-11-26 1982-11-25 Procedimiento para la preparacion de cetales de 3'-deshidro -cardenolido-tridigitoxosidos. Granted ES517673A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813146899 DE3146899A1 (de) 1981-11-26 1981-11-26 Neue ketale von 3'''-dehydro-cardenolid-tridigitoxosiden, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
ES8308890A1 true ES8308890A1 (es) 1983-08-16
ES517673A0 ES517673A0 (es) 1983-08-16

Family

ID=6147267

Family Applications (1)

Application Number Title Priority Date Filing Date
ES517673A Granted ES517673A0 (es) 1981-11-26 1982-11-25 Procedimiento para la preparacion de cetales de 3'-deshidro -cardenolido-tridigitoxosidos.

Country Status (17)

Country Link
US (1) US4436735A (es)
EP (1) EP0080675B1 (es)
JP (1) JPS5892699A (es)
KR (1) KR840002412A (es)
AT (1) ATE12238T1 (es)
AU (1) AU9075582A (es)
CA (1) CA1205071A (es)
DD (1) DD204928A5 (es)
DE (2) DE3146899A1 (es)
DK (1) DK523582A (es)
ES (1) ES517673A0 (es)
FI (1) FI824062L (es)
GR (1) GR77738B (es)
HU (1) HU185753B (es)
IL (1) IL67324A0 (es)
PT (1) PT75901B (es)
ZA (1) ZA828642B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0530224A1 (en) * 1990-05-07 1993-03-10 The Board Of Regents Of The University Of Washington Novel steroid glycosides useful in the early detection of hypertension
DE60218341D1 (de) * 2001-12-14 2007-04-05 Merck & Co Inc Neues, aus kulturfermentierungen isoliertes sordarinderivat und wirkungen als antipilzmittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE752284Q (en) * 1969-08-11 1970-12-21 Boehringer Mannheim Gmbh Digoxine ethers having pharmaceutical prop- - erties
BE759912A (fr) * 1969-12-05 1971-06-04 Boehringer Mannheim Gmbh Procede perfectionne de preparation d'ethers monomethyliques dedigoxin
DE2343400C3 (de) 1973-08-29 1979-11-08 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur 12 ß -Hydroxylierung von Digitalis-Glykosiden der A-Reihe
DE2354119A1 (de) 1973-10-29 1975-05-15 Boehringer Sohn Ingelheim Neue orthoformiatderivate des digitoxins, verfahren zu deren herstellung sowie diese enthaltende arzneimittel

Also Published As

Publication number Publication date
KR840002412A (ko) 1984-07-02
EP0080675A1 (de) 1983-06-08
FI824062L (fi) 1983-05-27
DK523582A (da) 1983-05-27
GR77738B (es) 1984-09-25
PT75901B (de) 1985-10-04
ATE12238T1 (de) 1985-04-15
EP0080675B1 (de) 1985-03-20
ES517673A0 (es) 1983-08-16
JPS5892699A (ja) 1983-06-02
DD204928A5 (de) 1983-12-14
CA1205071A (en) 1986-05-27
DE3146899A1 (de) 1983-06-01
FI824062A0 (fi) 1982-11-25
HU185753B (en) 1985-03-28
US4436735A (en) 1984-03-13
IL67324A0 (en) 1983-03-31
AU9075582A (en) 1983-06-02
ZA828642B (en) 1983-10-26
PT75901A (de) 1982-12-01
DE3262707D1 (en) 1985-04-25

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