ES8308299A1 - Procedimiento para la obtencion de nuevos derivados de cis-biciclo 3.3.0 octano. - Google Patents

Procedimiento para la obtencion de nuevos derivados de cis-biciclo 3.3.0 octano.

Info

Publication number
ES8308299A1
ES8308299A1 ES517545A ES517545A ES8308299A1 ES 8308299 A1 ES8308299 A1 ES 8308299A1 ES 517545 A ES517545 A ES 517545A ES 517545 A ES517545 A ES 517545A ES 8308299 A1 ES8308299 A1 ES 8308299A1
Authority
ES
Spain
Prior art keywords
compounds
medicines
bicyclo
cis
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES517545A
Other languages
English (en)
Spanish (es)
Other versions
ES517545A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Grünenthal GmbH
Original Assignee
Grünenthal GmbH
Chemie Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal GmbH, Chemie Gruenenthal GmbH filed Critical Grünenthal GmbH
Publication of ES517545A0 publication Critical patent/ES517545A0/es
Publication of ES8308299A1 publication Critical patent/ES8308299A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018—Esters of cycloaliphatic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES517545A 1981-11-21 1982-11-20 Procedimiento para la obtencion de nuevos derivados de cis-biciclo 3.3.0 octano. Expired ES8308299A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3146278A DE3146278C2 (de) 1981-11-21 1981-11-21 cis-Bicyclo[3.3.0]octanderivate, diese enthaltende Arzneimittel und Verfahren zur Herstellung dieser Verbindungen

Publications (2)

Publication Number Publication Date
ES517545A0 ES517545A0 (es) 1983-08-16
ES8308299A1 true ES8308299A1 (es) 1983-08-16

Family

ID=6146953

Family Applications (1)

Application Number Title Priority Date Filing Date
ES517545A Expired ES8308299A1 (es) 1981-11-21 1982-11-20 Procedimiento para la obtencion de nuevos derivados de cis-biciclo 3.3.0 octano.

Country Status (21)

Country Link
US (1) US4510323A (enExample)
EP (1) EP0080061B1 (enExample)
JP (1) JPS5892637A (enExample)
AT (1) ATE11668T1 (enExample)
AU (1) AU556560B2 (enExample)
CA (1) CA1202968A (enExample)
DD (1) DD207196A5 (enExample)
DE (2) DE3146278C2 (enExample)
DK (1) DK155934C (enExample)
ES (1) ES8308299A1 (enExample)
GR (1) GR77643B (enExample)
HK (1) HK40488A (enExample)
HU (1) HU187814B (enExample)
IE (1) IE53785B1 (enExample)
MY (1) MY8700890A (enExample)
PL (1) PL137185B1 (enExample)
PT (1) PT75694B (enExample)
SG (1) SG5788G (enExample)
SU (1) SU1225482A3 (enExample)
YU (1) YU42604B (enExample)
ZA (1) ZA826928B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3408699A1 (de) * 1984-03-08 1985-09-12 Schering AG, 1000 Berlin und 4709 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3914735A1 (de) * 1989-05-05 1990-11-08 Gruenenthal Gmbh Pharmakologisch wirksame ester, diese enthaltende arzneimittel und die herstellung dieser ester und arzneimittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201699A (en) * 1922-06-02 1923-08-09 Joseph Gardner Improvements in mechanical lubricators
DE2912409A1 (de) * 1978-03-31 1979-10-11 Ono Pharmaceutical Co 6,9-methano-pgi tief 2 -analoge
CA1201712A (en) * 1980-02-28 1986-03-11 Paul A. Aristoff Carbacyclin analogs
JPS56145239A (en) * 1980-04-11 1981-11-11 Sumitomo Chem Co Ltd Novel bicyclooctane derivative and its preparation

Also Published As

Publication number Publication date
US4510323A (en) 1985-04-09
AU556560B2 (en) 1986-11-06
ATE11668T1 (de) 1985-02-15
HK40488A (en) 1988-06-10
DE3146278C2 (de) 1984-10-31
PT75694B (de) 1985-01-10
JPH0336821B2 (enExample) 1991-06-03
YU42604B (en) 1988-10-31
SG5788G (en) 1989-06-02
DK513982A (da) 1983-05-22
DK155934B (da) 1989-06-05
ES517545A0 (es) 1983-08-16
HU187814B (en) 1986-02-28
ZA826928B (en) 1983-11-30
DK155934C (da) 1989-10-09
GR77643B (enExample) 1984-09-25
EP0080061B1 (de) 1985-02-06
IE53785B1 (en) 1989-02-15
AU8881382A (en) 1983-05-26
MY8700890A (en) 1987-12-31
DD207196A5 (de) 1984-02-22
PT75694A (de) 1982-11-01
DE3262233D1 (en) 1985-03-21
IE822252L (en) 1983-04-21
PL137185B1 (en) 1986-05-31
JPS5892637A (ja) 1983-06-02
CA1202968A (en) 1986-04-08
PL239099A1 (en) 1983-05-23
DE3146278A1 (de) 1983-06-01
YU257882A (en) 1985-03-20
SU1225482A3 (ru) 1986-04-15
EP0080061A1 (de) 1983-06-01

Similar Documents

Publication Publication Date Title
ES2071510T3 (es) Derivados de pirrolidina y de tiazolidina, su preparacion y los medicamentos que les contienen.
ES2196806T3 (es) Derivados de fenilurea y de feniltiourea.
GR1001619B (el) Παράγωγα ινδόλης.
AR009212A1 (es) Un derivado de 3-piperidil-4-oxoquinazolina; una composicion farmaceutica, un inhibidor de la proteina de transferencia de los trigliceridos microsomal(mtp) y un agente terapeutico o preventivo para la hiperlipemia o la arteriosclerosis que lo contienen
KR950700323A (ko) 엔케팔리나제 및 안지오텐신 전환 효소의 억제제로서 유용한 아미노아세틸머캅토아세틸아미드 유도체(Aminoacetylmercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ACE)
ES8206491A1 (es) Un procedimiento para la preparacion de derivados de 2,4-diaminoquinazolina.
FR2430932A1 (fr) Metaphenylenediamines et compositions tinctoriales les contenant
ES2087477T3 (es) Derivados de pirimidina-4-carboxamida, su preparacion y su aplicacion en terapeutica.
ES2126370T3 (es) Nuevos derivados de n,n'-di(aralquil)-n,n'-di(2-azaaralquil)alquilenodiamina y su utilizacion en unas composiciones farmaceuticas y cosmeticas.
ES8801618A1 (es) Un procedimiento para preparar derivados de arilciclobutilalquilamina
MX168030B (es) Procedimiento para la preparacion de derivados de alcano y alcoxialcano
MX3488E (es) Procedimiento para la preparacion de derivados de oxadiazolinona
ES2032752T3 (es) Procedimiento de preparacion de derivados de la 1-bencenosulfonil-2-oxo-5-alcoxi-pirrolidina.
ES2001094A6 (es) Un procedimiento para la preparacion de un derivado de guanina
AR010098A1 (es) COMPOSICION Y PROCEDIMIENTO PARA LA DEFORMACION PERMANENTE DEL CABELLO, Y PROCEDIMIENTO DE PREPARACIoN DE DICHA COMPOSICION
ES2189736T3 (es) Derivados de la benzamida y medicamentos que los contienen.
AR002749A1 (es) Derivados de estiril bencimidazol y composicion farmaceutica que los comprende.
ES8504179A1 (es) "procedimiento para preparar derivados de 1,4-dihidropiridina".
ES8707498A1 (es) Un procedimiento para preparar derivados de azetidinona
DK0745081T3 (da) Indan-2-mercaptoacetylamiddisulfidderivater, der er anvendelige som enkephalinase-inhibitorer
ES2023151B3 (es) Derivados de p-hidroxicinamamida e inhibidor de melanina que los contiene.
AR220300A1 (es) Nuevos compuestos derivados de 2,2'-dimetil-3'-vinil-ciclopropanocarboxilato de 4-fenil-,bencil o alquil(c1-c4)maleimidometilo,procedimiento para obtenerlos y composiciones insecticidas que los contienen
ES2135824T3 (es) Derivados de 6h-dibenz(c,e)(1,2)oxafosforin-6-oxido para la estabilizacion de 3,4-epoxiciclohexilmetil(met)acrilato.
ES8402819A1 (es) Procedimiento para la produccion de una 3,3-dialquil-o 3,3-dialquileno-indolina.
ES8300091A1 (es) Procedimiento para preparar derivados de indol o de indolina

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519