ES8307208A1 - Un procedimiento para la produccion de un derivado de acido cinamoilantralinico sustituido en el nucleo. - Google Patents

Un procedimiento para la produccion de un derivado de acido cinamoilantralinico sustituido en el nucleo.

Info

Publication number
ES8307208A1
ES8307208A1 ES515401A ES515401A ES8307208A1 ES 8307208 A1 ES8307208 A1 ES 8307208A1 ES 515401 A ES515401 A ES 515401A ES 515401 A ES515401 A ES 515401A ES 8307208 A1 ES8307208 A1 ES 8307208A1
Authority
ES
Spain
Prior art keywords
intermediates
production
nuclear substituted
acid derivatives
substituted cinnamoylanthranilic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES515401A
Other languages
English (en)
Other versions
ES515401A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Publication of ES515401A0 publication Critical patent/ES515401A0/es
Publication of ES8307208A1 publication Critical patent/ES8307208A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ACIDO CINAMOILANTRANILICO, SUSTITUIDOS EN EL NUCLEO, DE FORMULA (I), EN LA QUE R Y R SON HIDROXI O ALCOXI C <- . CONSISTE EN LA REACCION DE UN DERIVADO DE BENZALDEHIDO DE FORMULA (II), CON ACIDO 2-CARBOXIMALONANILICO Y UNA AMINA CICLICA, DE FORMULA (III), EN LAS QUE X ES METILENO U OXIGENO, N VALE 1 O 2, Y R Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), EN UN DISOLVENTE ORGANICO INERTE; SEGUIDA DEL TRATAMIENTO DEL PRODUCTO FORMADO CON UN REACTIVO ACIDO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ASMA, FIEBRE DEL HENO, DERMATITIS ATOPICA Y URTICARIA.
ES515401A 1981-09-01 1982-08-31 Un procedimiento para la produccion de un derivado de acido cinamoilantralinico sustituido en el nucleo. Expired ES8307208A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56137344A JPS5838244A (ja) 1981-09-01 1981-09-01 核置換シンナモイルアントラニル酸塩およびその製造方法

Publications (2)

Publication Number Publication Date
ES515401A0 ES515401A0 (es) 1983-07-01
ES8307208A1 true ES8307208A1 (es) 1983-07-01

Family

ID=15196441

Family Applications (1)

Application Number Title Priority Date Filing Date
ES515401A Expired ES8307208A1 (es) 1981-09-01 1982-08-31 Un procedimiento para la produccion de un derivado de acido cinamoilantralinico sustituido en el nucleo.

Country Status (13)

Country Link
US (2) US4486597A (es)
EP (1) EP0074725B1 (es)
JP (1) JPS5838244A (es)
AT (1) ATE17115T1 (es)
AU (1) AU562861B2 (es)
CA (1) CA1189090A (es)
DE (1) DE3268129D1 (es)
DK (1) DK158467C (es)
ES (1) ES8307208A1 (es)
FI (1) FI75148C (es)
HU (1) HU186968B (es)
NO (1) NO159849C (es)
PT (1) PT75452B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536346A (en) * 1983-05-06 1985-08-20 American Cyanamid Company Aralkanamidophenyl compounds
JPS60214766A (ja) * 1984-04-04 1985-10-28 Terumo Corp アミド誘導体およびこれを有効成分として含有する５−リポキシゲナ−ゼ作用阻害剤
JPH0784424B2 (ja) * 1987-04-15 1995-09-13 味の素株式会社 チロシン誘導体及びその用途
KR970006473B1 (ko) * 1987-06-08 1997-04-28 오노 화아마슈티칼 캄파니 리미팃드 신나모일아미드 유도체, 그들의 제조방법, 그들을 함유하는 제약학적 조성물 및 그들의 사용
WO2002055454A2 (en) * 2001-01-10 2002-07-18 Smithkline Beecham Corporation Process and product
DE10208778B4 (de) * 2002-02-28 2004-08-12 Thyssenkrupp Stahl Ag Aus Stahl-Hohlprofilen gebildete Tragstruktur für Fahrzeuge
DE10254872A1 (de) 2002-11-25 2004-06-03 Symrise Gmbh & Co. Kg Anthranilsäureamide und deren Derivate als kosmetische und pharmazeutische Wirkstoffe
KR101593708B1 (ko) * 2007-12-21 2016-02-12 피브로테크 세라퓨틱 피티와이 엘티디 항섬유증 제제의 할로겐화 유사체

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755603A (en) * 1970-07-01 1973-08-28 Syntex Corp Biphenylyloxyacetic acids in pharmaceutical compositions
JPS5640710B2 (es) * 1973-01-18 1981-09-22
JPS5848545B2 (ja) * 1974-04-18 1983-10-28 キツセイヤクヒンコウギヨウ カブシキガイシヤ シンキホウコウゾクカルボンサンアミドユウドウタイ ノ セイゾウホウホウ
JPS511440A (ja) * 1974-04-18 1976-01-08 Kissei Pharmaceutical Shinkihokozokukarubonsanjudotai no seizohoho
US4337270A (en) * 1980-05-21 1982-06-29 Hisamitsu Pharmaceutical Co., Inc. Novel anthranilic acid derivatives
JPS568858A (en) * 1980-06-23 1981-01-29 Hitachi Ltd Resin sealing type semiconductor device

Also Published As

Publication number Publication date
FI822953L (fi) 1983-03-02
FI822953A0 (fi) 1982-08-25
US4623724A (en) 1986-11-18
NO159849C (no) 1989-02-15
DK158467C (da) 1990-10-22
JPS5838244A (ja) 1983-03-05
DK158467B (da) 1990-05-21
NO822943L (no) 1983-03-02
EP0074725B1 (en) 1985-12-27
CA1189090A (en) 1985-06-18
ES515401A0 (es) 1983-07-01
EP0074725A1 (en) 1983-03-23
FI75148B (fi) 1988-01-29
HU186968B (en) 1985-10-28
DE3268129D1 (en) 1986-02-06
ATE17115T1 (de) 1986-01-15
AU8714882A (en) 1983-03-10
US4486597A (en) 1984-12-04
AU562861B2 (en) 1987-06-18
PT75452A (en) 1982-09-01
PT75452B (en) 1984-11-19
FI75148C (fi) 1988-05-09
NO159849B (no) 1988-11-07
JPH0136462B2 (es) 1989-07-31
DK389582A (da) 1983-03-02

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