ES8307202A1 - "procedimiento para preparar un acido alcanoico substituido en posicion alfa con un grupo aromatico, opticamente activo". - Google Patents
"procedimiento para preparar un acido alcanoico substituido en posicion alfa con un grupo aromatico, opticamente activo".Info
- Publication number
- ES8307202A1 ES8307202A1 ES513077A ES513077A ES8307202A1 ES 8307202 A1 ES8307202 A1 ES 8307202A1 ES 513077 A ES513077 A ES 513077A ES 513077 A ES513077 A ES 513077A ES 8307202 A1 ES8307202 A1 ES 8307202A1
- Authority
- ES
- Spain
- Prior art keywords
- optically active
- aromatic
- alkanones
- substituted
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 239000002841 Lewis acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001335 aliphatic alkanes Chemical class 0.000 abstract 1
- 230000001760 anti-analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 150000001491 aromatic compounds Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 239000002917 insecticide Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ACIDOS ALCANOICOS SUSTITUIDOS EN POSICION ALFA CON UN GRUPO AROMATICO, OPTICAMENTE ACTIVOS, DE SUS ESTERES Y DE SUS ACIDOS, DE FORMULA (I), EN LA QUE AR ES UN GRUPO AROMATICO; R ES ALQUILO; Y R ES HIDROGENO, ALCOHILO O HIDROXIALCOHILO. CONSISTE EN LA REACCION DE UN HALOGENURO DE ACIDO, OPTICAMENTE ACTIVO, DE FORMULA (II) CON UN COMPUESTO AROMATICO DE FORMULA ARH, EN LAS QUE X ES HALOGENO O SULFONILOXI, Y ES HALOGENO, Y R Y AR TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I); SEGUIDA DE LA TRANSPOSICION DE LA L-ALCANONA FORMADA. LA REACCION SE EFECTUA EN PRESENCIA DE UN ACIDO DE LEWIS, A UNA TEMPERATURA ENTRE -10 C Y 100 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANALGESICOS, ANTIINFLAMATORIOS Y ANTIPIRETICOS Y COMO AGENTES HERBICIDAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56090978A JPS5810525A (ja) | 1981-06-15 | 1981-06-15 | 光学活性な1−芳香族基置換−1−アルカノン類の製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES513077A0 ES513077A0 (es) | 1983-06-01 |
ES8307202A1 true ES8307202A1 (es) | 1983-06-01 |
Family
ID=14013600
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES513077A Expired ES8307202A1 (es) | 1981-06-15 | 1982-06-14 | "procedimiento para preparar un acido alcanoico substituido en posicion alfa con un grupo aromatico, opticamente activo". |
Country Status (14)
Country | Link |
---|---|
US (1) | US4539420A (es) |
EP (1) | EP0067698A3 (es) |
JP (1) | JPS5810525A (es) |
KR (1) | KR840000463A (es) |
AU (1) | AU8479782A (es) |
DK (1) | DK267482A (es) |
ES (1) | ES8307202A1 (es) |
FI (1) | FI822132A0 (es) |
HU (1) | HU186526B (es) |
IL (1) | IL66055A0 (es) |
NO (2) | NO821971L (es) |
PL (1) | PL236908A1 (es) |
PT (1) | PT75049B (es) |
ZA (1) | ZA824179B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4654438A (en) * | 1981-04-30 | 1987-03-31 | Syntex Pharmaceuticals International Limited | Manufacture of alpha-arylalkanoic acids and precursors |
FI82680C (fi) * | 1981-12-11 | 1991-04-10 | Syntex Pharma Int | Framstaellning av - arylalkansyror. |
IT1212709B (it) * | 1983-03-07 | 1989-11-30 | Zambon Spa | Alfa-alogenoalchilarilchetali particolarmente utili per la sintesi di acidi alfa-arilalcanoici. |
DE3404336A1 (de) * | 1984-02-08 | 1985-08-08 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von estern optisch aktiver 2-arylalkansaeuren |
ATE39691T1 (de) * | 1984-04-06 | 1989-01-15 | Zambon Spa | Optisch wirksame ketale, verfahren zu deren herstellung und deren verwendung in der synthese von alpha-arylalkansaeuren. |
IT1174084B (it) * | 1984-05-10 | 1987-07-01 | Blaschim Spa | Procentimento per preparare il naproxen |
IT1190362B (it) * | 1985-05-30 | 1988-02-16 | Zambon Spa | Preparazione del (6-metossi-2-naftil)-(1-bormoetil)-chetone e dei suoi derivati |
IT1188181B (it) * | 1985-07-31 | 1988-01-07 | Zambon Spa | Processo per la preparazione di acidi carbossilici otticamente attivi e relativi intermedi |
IT1201443B (it) * | 1985-07-31 | 1989-02-02 | Zambon Spa | Intermedi per la sintesi di acidi carbossilici |
JPH0692653B2 (ja) * | 1987-05-13 | 1994-11-16 | 大阪セメント株式会社 | 粉粒体材料充填装置 |
EP0421600A1 (en) * | 1989-09-01 | 1991-04-10 | Schering Corporation | Asymmetric chemical synthesis and intermediates for making antifungal compounds |
US5264577A (en) * | 1992-04-22 | 1993-11-23 | Warner-Lambert Company | Cyclic amino acids and derivatives thereof |
FR2723942B1 (fr) * | 1994-08-24 | 1996-09-27 | Rhone Poulenc Chimie | Procede d'acylation d'ethers aromatiques |
FR2739098B1 (fr) * | 1995-09-25 | 1997-11-28 | Rhone Poulenc Chimie | Procede d'acylation d'un compose aromatique |
KR100433268B1 (ko) * | 2000-10-05 | 2004-05-31 | 대한민국 | 악취물질의 생물학적 처리용 발효제 조성물 및 그 제조방법 |
US20050245764A1 (en) * | 2001-08-08 | 2005-11-03 | Koki Yamashita | Process for producing optically active 2-substituted carboxylic acid |
CN106008183B (zh) * | 2016-06-07 | 2019-05-07 | 浙江普洛康裕制药有限公司 | 麻黄碱或伪麻黄碱及麻黄碱或伪麻黄碱中间体的制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1473806A (fr) * | 1960-04-07 | 1967-03-24 | Thomae Gmbh Dr K | Procédé pour préparer des alpha-pyrrolidinocétones |
JPS5312837A (en) * | 1976-07-23 | 1978-02-04 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid derivatives |
GB1578360A (en) * | 1976-12-21 | 1980-11-05 | Merck & Co Inc | Production of methyl varillyl ketone |
US4169858A (en) * | 1976-12-21 | 1979-10-02 | Merck & Co., Inc. | Process for preparing a ketone |
DE2808459A1 (de) * | 1977-05-17 | 1979-08-30 | Merck Patent Gmbh | Hydroxyalkylphenone und ihre verwendung als photosensibilisatoren |
DE2722264C2 (de) * | 1977-05-17 | 1984-06-28 | Merck Patent Gmbh, 6100 Darmstadt | Verwendung von substituierten Oxyalkylphenonen als Photosensibilisatoren |
IL56878A (en) * | 1978-03-31 | 1984-03-30 | Rhone Poulenc Inc | Ketoximinoethers and their use as insecticides |
IT1109200B (it) * | 1979-02-20 | 1985-12-16 | Montedison Spa | Processo per la preparazione di esteri di acidi arilacetici da alfa-alo-alchilarilchetoni |
IE50898B1 (en) * | 1980-02-26 | 1986-08-06 | Blaschim Spa | Process for preparing esters of 2-(6'-methoxy-2'-naphthyl)-propionic acid via rearrangement of new ketals of 2-halo-1-(6'-methoxy-2'-naphthyl)-propan-1-one |
NZ198271A (en) * | 1980-09-11 | 1985-05-31 | Syntex Pharma Int | Preparation of alpha-aromatic-substituted alkanoic acids and intermediates |
-
1981
- 1981-06-15 JP JP56090978A patent/JPS5810525A/ja active Granted
-
1982
- 1982-06-11 AU AU84797/82A patent/AU8479782A/en not_active Abandoned
- 1982-06-11 US US06/387,585 patent/US4539420A/en not_active Expired - Fee Related
- 1982-06-14 ES ES513077A patent/ES8307202A1/es not_active Expired
- 1982-06-14 FI FI822132A patent/FI822132A0/fi not_active Application Discontinuation
- 1982-06-14 PL PL23690882A patent/PL236908A1/xx unknown
- 1982-06-14 HU HU821915A patent/HU186526B/hu unknown
- 1982-06-14 DK DK267482A patent/DK267482A/da not_active Application Discontinuation
- 1982-06-14 EP EP82303068A patent/EP0067698A3/en not_active Withdrawn
- 1982-06-14 ZA ZA824179A patent/ZA824179B/xx unknown
- 1982-06-14 IL IL66055A patent/IL66055A0/xx unknown
- 1982-06-14 NO NO821971A patent/NO821971L/no unknown
- 1982-06-14 PT PT75049A patent/PT75049B/pt unknown
- 1982-06-14 KR KR1019820002636A patent/KR840000463A/ko unknown
-
1983
- 1983-03-03 NO NO830730A patent/NO830730L/no unknown
Also Published As
Publication number | Publication date |
---|---|
PT75049A (en) | 1982-07-01 |
DK267482A (da) | 1982-12-16 |
JPH0255408B2 (es) | 1990-11-27 |
EP0067698A2 (en) | 1982-12-22 |
AU8479782A (en) | 1983-01-20 |
NO821971L (no) | 1982-12-16 |
PL236908A1 (en) | 1983-02-28 |
FI822132A0 (fi) | 1982-06-14 |
ES513077A0 (es) | 1983-06-01 |
HUT35235A (en) | 1985-06-28 |
PT75049B (en) | 1984-02-21 |
HU186526B (en) | 1985-08-28 |
US4539420A (en) | 1985-09-03 |
ZA824179B (en) | 1984-01-25 |
NO830730L (no) | 1982-12-16 |
EP0067698A3 (en) | 1983-10-05 |
JPS5810525A (ja) | 1983-01-21 |
KR840000463A (ko) | 1984-02-22 |
IL66055A0 (en) | 1982-09-30 |
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