ES8304202A1 - Un metodo de produccion del antibiotico narasina. - Google Patents

Un metodo de produccion del antibiotico narasina.

Info

Publication number
ES8304202A1
ES8304202A1 ES511916A ES511916A ES8304202A1 ES 8304202 A1 ES8304202 A1 ES 8304202A1 ES 511916 A ES511916 A ES 511916A ES 511916 A ES511916 A ES 511916A ES 8304202 A1 ES8304202 A1 ES 8304202A1
Authority
ES
Spain
Prior art keywords
narasin
preparing
producing
carbohydrate
variant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511916A
Other languages
English (en)
Other versions
ES511916A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES8304202A1 publication Critical patent/ES8304202A1/es
Publication of ES511916A0 publication Critical patent/ES511916A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

METODO DE PRODUCCION DEL ANTIBIOTICO NARASINA. SE CULTIVA ~ASTREPTOMYCES GRANULORUBER~B NRRL 12389 O UN MUTANTE O VARIANTE DEL MISMO, PRODUCTOR DE NARASINA, EN UN MEDIO DE CULTIVO QUE CONTIENE FUENTES ASIMILABLES DE HIDRATOS DE CARBONO, NITROGENO Y SALES INORGANICAS, BAJO CONDICIONES DE FERMENTACION AEROBIA SUMERGIDA, HASTA QUE EL CITADO ORGANISMO PRODUCE EN EL MEDIO DE CULTIVO MENCIONADO UNA CANTIDAD SUSTANCIAL DE ACTIVIDAD ANTIBIOTICA. POSTERIORMENTE SE SEPARA LA NARASINA DEL MEDIO DE CULTIVO. SE UTILIZA CONTRA LAS BACTERIAS GRAM-POSITIVAS, BACTERIAS ANAEROBIAS Y LOS HONGOS Y ES UTIL COMO AGENTE ANTICOCCIDIAL Y COMO AGENTE PARA AUMENTAR LA UTILIZACION DEL PIENSO EN LOS RUMIANTES.
ES511916A 1981-05-06 1982-05-04 Un metodo de produccion del antibiotico narasina. Granted ES511916A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/261,068 US4342829A (en) 1981-05-06 1981-05-06 Process for preparing narasin

Publications (2)

Publication Number Publication Date
ES8304202A1 true ES8304202A1 (es) 1983-02-16
ES511916A0 ES511916A0 (es) 1983-02-16

Family

ID=22991818

Family Applications (1)

Application Number Title Priority Date Filing Date
ES511916A Granted ES511916A0 (es) 1981-05-06 1982-05-04 Un metodo de produccion del antibiotico narasina.

Country Status (25)

Country Link
US (1) US4342829A (es)
EP (1) EP0064409B1 (es)
JP (1) JPS57202291A (es)
KR (1) KR850001230B1 (es)
AR (1) AR227589A1 (es)
AT (1) ATE10289T1 (es)
AU (1) AU557316B2 (es)
CA (1) CA1177425A (es)
CS (1) CS227700B2 (es)
DD (1) DD202589A5 (es)
DE (1) DE3261230D1 (es)
DK (1) DK201682A (es)
EG (1) EG15730A (es)
ES (1) ES511916A0 (es)
FI (1) FI70595C (es)
GB (1) GB2097794B (es)
GR (1) GR76520B (es)
HU (1) HU189578B (es)
IE (1) IE52295B1 (es)
IL (1) IL65691A (es)
PH (1) PH17799A (es)
PL (1) PL129644B1 (es)
PT (1) PT74842B (es)
RO (1) RO84111B (es)
ZA (1) ZA823056B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513086A (en) * 1981-10-15 1985-04-23 Eli Lilly And Company Cloning vectors for use in streptomyces and related organisms
US5444043A (en) * 1994-02-18 1995-08-22 The Regents Of The University Of California Cyclic heptapeptide anti-inflammatory agent
TWI656872B (zh) 2014-11-13 2019-04-21 美商益農美國公司 甲基鹽黴素於豬飼料中之抗病毒效果

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038384A (en) * 1974-06-10 1977-07-26 Eli Lilly And Company Antibiotic a-28086 and process for production thereof
US4309504A (en) * 1980-01-28 1982-01-05 Eli Lilly And Company Process for preparing narasin

Also Published As

Publication number Publication date
ATE10289T1 (de) 1984-11-15
GB2097794A (en) 1982-11-10
DE3261230D1 (de) 1984-12-20
US4342829A (en) 1982-08-03
FI70595C (fi) 1986-09-24
IE52295B1 (en) 1987-09-02
AR227589A1 (es) 1982-11-15
CS227700B2 (en) 1984-05-14
PT74842A (en) 1982-06-01
AU8341282A (en) 1982-11-11
DK201682A (da) 1982-11-07
FI821548A0 (fi) 1982-05-03
FI821548L (fi) 1982-11-07
GR76520B (es) 1984-08-10
RO84111A (ro) 1984-05-23
GB2097794B (en) 1985-10-02
KR830010197A (ko) 1983-12-26
KR850001230B1 (ko) 1985-08-23
IL65691A (en) 1985-05-31
HU189578B (en) 1986-07-28
EG15730A (en) 1986-09-30
RO84111B (ro) 1984-07-30
CA1177425A (en) 1984-11-06
IE821067L (en) 1982-11-06
PT74842B (en) 1985-06-28
EP0064409B1 (en) 1984-11-14
JPS57202291A (en) 1982-12-11
PL129644B1 (en) 1984-05-31
ZA823056B (en) 1983-03-30
IL65691A0 (en) 1982-08-31
PH17799A (en) 1984-12-13
ES511916A0 (es) 1983-02-16
PL236281A1 (es) 1982-11-08
FI70595B (fi) 1986-06-06
EP0064409A1 (en) 1982-11-10
AU557316B2 (en) 1986-12-18
DD202589A5 (de) 1983-09-21

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