ES8303442A1 - "procedimiento para la preparacion de plasminogeno practicamente exento de virus de hepatitis". - Google Patents

"procedimiento para la preparacion de plasminogeno practicamente exento de virus de hepatitis".

Info

Publication number
ES8303442A1
ES8303442A1 ES511982A ES511982A ES8303442A1 ES 8303442 A1 ES8303442 A1 ES 8303442A1 ES 511982 A ES511982 A ES 511982A ES 511982 A ES511982 A ES 511982A ES 8303442 A1 ES8303442 A1 ES 8303442A1
Authority
ES
Spain
Prior art keywords
plasminogen
prepared
preparation
plasmin
saccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511982A
Other languages
English (en)
Other versions
ES511982A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Publication of ES8303442A1 publication Critical patent/ES8303442A1/es
Publication of ES511982A0 publication Critical patent/ES511982A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE PLASMINOGENO PRACTICAMENTE EXENTO DE VIRUS DE HEPATITIS. CONSISTE EN EL CALENTAMIENTO DE UNA DISOLUCION DE PLASMINOGENO, QUE CONTIENE UN AMINOACIDO EN CONCENTRACION NO INFERIOR A 3 MOLES/LITRO Y/O UN SACARIDO, ASI COMO UN INHIBIDOR DE PROTEINASA CON ESPECIFICIDAD PARA PLASMINA, TAL COMO APROTIMINA. EL CALENTAMIENTO SE EFECTUA A TEMPERATURAS ENTRE 30 C Y 100 C DURANTE 1 MINUTO A 48 HORAS. ESTE COMPUESTO TIENE APLICACIONES PARA EL TRATAMIENTO DE LA TROMBOLISIS.
ES511982A 1981-05-14 1982-05-07 "procedimiento para la preparacion de plasminogeno practicamente exento de virus de hepatitis". Granted ES511982A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813119157 DE3119157A1 (de) 1981-05-14 1981-05-14 Verfahren zur herstellung von und danach hergestelltes plasminogen

Publications (2)

Publication Number Publication Date
ES8303442A1 true ES8303442A1 (es) 1983-02-01
ES511982A0 ES511982A0 (es) 1983-02-01

Family

ID=6132282

Family Applications (1)

Application Number Title Priority Date Filing Date
ES511982A Granted ES511982A0 (es) 1981-05-14 1982-05-07 "procedimiento para la preparacion de plasminogeno practicamente exento de virus de hepatitis".

Country Status (11)

Country Link
US (1) US4442213A (es)
EP (1) EP0065256B1 (es)
JP (1) JPS57193418A (es)
AT (1) ATE21824T1 (es)
AU (1) AU547139B2 (es)
CA (1) CA1187411A (es)
DE (2) DE3119157A1 (es)
ES (1) ES511982A0 (es)
IL (1) IL65752A (es)
MX (1) MX7033E (es)
NZ (1) NZ200589A (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604358A (en) * 1983-04-14 1986-08-05 Armour Pharmaceutical Company Preparation of pasteurized human plasminogen
DE3584902D1 (de) * 1984-02-29 1992-01-30 Asahi Chemical Ind Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren.
US4699525A (en) * 1985-07-18 1987-10-13 Ebara Corporation Thrust bearing
JPS62153224A (ja) * 1985-12-27 1987-07-08 Green Cross Corp:The プラスミノゲン製剤
US4857320A (en) * 1987-02-19 1989-08-15 Monsanto Company Method of enhancing the solubility of tissue plasminogen activator
AT402367B (de) * 1990-10-11 1997-04-25 Immuno Ag Pharmazeutische zubereitung auf basis von lys-plasminogen
EP0835931A4 (en) * 1995-06-26 2000-11-15 Daiichi Pure Chemicals Co Ltd STABLE PLASMINE SOLUTION
US6969515B2 (en) 1999-11-13 2005-11-29 Talecris Biotherapeutics, Inc. Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
US6964764B2 (en) * 1999-11-13 2005-11-15 Talecris Biotherapeutics, Inc. Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
US7544500B2 (en) * 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
US6355243B1 (en) * 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
BRPI0913397B8 (pt) * 2008-06-04 2021-05-25 Grifols Therapeutics Inc método para preparar plasmina
JP5789521B2 (ja) 2009-03-03 2015-10-07 グリフオルス・セラピユーテイクス・インコーポレーテツドＧｒｉｆｏｌｓ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． プラスミノーゲンを製造するための組成物、方法およびキット；ならびにそれから製造されるプラスミン
EP3233111B1 (en) * 2014-12-19 2024-08-07 Kedrion Biopharma Inc. Pharmaceutical composition comprising plasminogen and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2347048A2 (fr) * 1976-04-07 1977-11-04 Choay Sa Compositions constituees par des composes du type plasminogene, notamment d'origine placentaire, procede d'obtention des ces compositions, et medicaments contenant ces compositions
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
JPS5716824A (en) * 1980-07-03 1982-01-28 Green Cross Corp:The Plasminogen pharmaceutical and stabilizing method thereof
GB2068002B (en) * 1980-01-25 1983-06-29 Green Cross Corp Plasminogen preparation and their production
JPS56106594A (en) * 1980-01-25 1981-08-24 Green Cross Corp:The Stabilizing method of plasminogen
FR2504921A1 (fr) * 1981-04-30 1982-11-05 Choay Sa Medicament nouveau constitue par un complexe aprotinine-plasmine et procede de preparation de ce nouveau complexe

Also Published As

Publication number Publication date
DE3272987D1 (en) 1986-10-09
JPS57193418A (en) 1982-11-27
DE3119157A1 (de) 1982-12-09
AU547139B2 (en) 1985-10-10
ATE21824T1 (de) 1986-09-15
JPH0366292B2 (es) 1991-10-16
US4442213A (en) 1984-04-10
ES511982A0 (es) 1983-02-01
EP0065256B1 (de) 1986-09-03
NZ200589A (en) 1985-04-30
EP0065256A3 (en) 1984-01-18
IL65752A (en) 1985-05-31
AU8366182A (en) 1982-11-18
CA1187411A (en) 1985-05-21
MX7033E (es) 1987-03-03
IL65752A0 (en) 1982-08-31
EP0065256A2 (de) 1982-11-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010402