ES8303442A1 - "procedimiento para la preparacion de plasminogeno practicamente exento de virus de hepatitis". - Google Patents
"procedimiento para la preparacion de plasminogeno practicamente exento de virus de hepatitis".Info
- Publication number
- ES8303442A1 ES8303442A1 ES511982A ES511982A ES8303442A1 ES 8303442 A1 ES8303442 A1 ES 8303442A1 ES 511982 A ES511982 A ES 511982A ES 511982 A ES511982 A ES 511982A ES 8303442 A1 ES8303442 A1 ES 8303442A1
- Authority
- ES
- Spain
- Prior art keywords
- plasminogen
- prepared
- preparation
- plasmin
- saccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/484—Plasmin (3.4.21.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE PLASMINOGENO PRACTICAMENTE EXENTO DE VIRUS DE HEPATITIS. CONSISTE EN EL CALENTAMIENTO DE UNA DISOLUCION DE PLASMINOGENO, QUE CONTIENE UN AMINOACIDO EN CONCENTRACION NO INFERIOR A 3 MOLES/LITRO Y/O UN SACARIDO, ASI COMO UN INHIBIDOR DE PROTEINASA CON ESPECIFICIDAD PARA PLASMINA, TAL COMO APROTIMINA. EL CALENTAMIENTO SE EFECTUA A TEMPERATURAS ENTRE 30 C Y 100 C DURANTE 1 MINUTO A 48 HORAS. ESTE COMPUESTO TIENE APLICACIONES PARA EL TRATAMIENTO DE LA TROMBOLISIS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813119157 DE3119157A1 (de) | 1981-05-14 | 1981-05-14 | Verfahren zur herstellung von und danach hergestelltes plasminogen |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8303442A1 true ES8303442A1 (es) | 1983-02-01 |
ES511982A0 ES511982A0 (es) | 1983-02-01 |
Family
ID=6132282
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES511982A Granted ES511982A0 (es) | 1981-05-14 | 1982-05-07 | "procedimiento para la preparacion de plasminogeno practicamente exento de virus de hepatitis". |
Country Status (11)
Country | Link |
---|---|
US (1) | US4442213A (es) |
EP (1) | EP0065256B1 (es) |
JP (1) | JPS57193418A (es) |
AT (1) | ATE21824T1 (es) |
AU (1) | AU547139B2 (es) |
CA (1) | CA1187411A (es) |
DE (2) | DE3119157A1 (es) |
ES (1) | ES511982A0 (es) |
IL (1) | IL65752A (es) |
MX (1) | MX7033E (es) |
NZ (1) | NZ200589A (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4604358A (en) * | 1983-04-14 | 1986-08-05 | Armour Pharmaceutical Company | Preparation of pasteurized human plasminogen |
DE3584902D1 (de) * | 1984-02-29 | 1992-01-30 | Asahi Chemical Ind | Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren. |
US4699525A (en) * | 1985-07-18 | 1987-10-13 | Ebara Corporation | Thrust bearing |
JPS62153224A (ja) * | 1985-12-27 | 1987-07-08 | Green Cross Corp:The | プラスミノゲン製剤 |
US4857320A (en) * | 1987-02-19 | 1989-08-15 | Monsanto Company | Method of enhancing the solubility of tissue plasminogen activator |
AT402367B (de) * | 1990-10-11 | 1997-04-25 | Immuno Ag | Pharmazeutische zubereitung auf basis von lys-plasminogen |
EP0835931A4 (en) * | 1995-06-26 | 2000-11-15 | Daiichi Pure Chemicals Co Ltd | STABLE PLASMINE SOLUTION |
US6969515B2 (en) | 1999-11-13 | 2005-11-29 | Talecris Biotherapeutics, Inc. | Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin |
US6964764B2 (en) * | 1999-11-13 | 2005-11-15 | Talecris Biotherapeutics, Inc. | Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin |
US7544500B2 (en) * | 1999-11-13 | 2009-06-09 | Talecris Biotherapeutics, Inc. | Process for the production of a reversibly inactive acidified plasmin composition |
US6355243B1 (en) * | 1999-11-13 | 2002-03-12 | Bayer Corporation | Method of thrombolysis by local delivery of active plasmin |
BRPI0913397B8 (pt) * | 2008-06-04 | 2021-05-25 | Grifols Therapeutics Inc | método para preparar plasmina |
JP5789521B2 (ja) | 2009-03-03 | 2015-10-07 | グリフオルス・セラピユーテイクス・インコーポレーテツドGrifols Therapeutics,Inc. | プラスミノーゲンを製造するための組成物、方法およびキット;ならびにそれから製造されるプラスミン |
EP3233111B1 (en) * | 2014-12-19 | 2024-08-07 | Kedrion Biopharma Inc. | Pharmaceutical composition comprising plasminogen and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2347048A2 (fr) * | 1976-04-07 | 1977-11-04 | Choay Sa | Compositions constituees par des composes du type plasminogene, notamment d'origine placentaire, procede d'obtention des ces compositions, et medicaments contenant ces compositions |
DE2916711A1 (de) * | 1979-04-25 | 1980-11-06 | Behringwerke Ag | Blutgerinnungsfaktoren und verfahren zu ihrer herstellung |
JPS5716824A (en) * | 1980-07-03 | 1982-01-28 | Green Cross Corp:The | Plasminogen pharmaceutical and stabilizing method thereof |
GB2068002B (en) * | 1980-01-25 | 1983-06-29 | Green Cross Corp | Plasminogen preparation and their production |
JPS56106594A (en) * | 1980-01-25 | 1981-08-24 | Green Cross Corp:The | Stabilizing method of plasminogen |
FR2504921A1 (fr) * | 1981-04-30 | 1982-11-05 | Choay Sa | Medicament nouveau constitue par un complexe aprotinine-plasmine et procede de preparation de ce nouveau complexe |
-
1981
- 1981-05-14 DE DE19813119157 patent/DE3119157A1/de not_active Withdrawn
-
1982
- 1982-05-07 ES ES511982A patent/ES511982A0/es active Granted
- 1982-05-11 EP EP82104059A patent/EP0065256B1/de not_active Expired
- 1982-05-11 AT AT82104059T patent/ATE21824T1/de not_active IP Right Cessation
- 1982-05-11 DE DE8282104059T patent/DE3272987D1/de not_active Expired
- 1982-05-12 US US06/377,312 patent/US4442213A/en not_active Expired - Lifetime
- 1982-05-12 IL IL65752A patent/IL65752A/xx not_active IP Right Cessation
- 1982-05-12 NZ NZ200589A patent/NZ200589A/xx unknown
- 1982-05-13 JP JP57079248A patent/JPS57193418A/ja active Granted
- 1982-05-13 AU AU83661/82A patent/AU547139B2/en not_active Ceased
- 1982-05-13 MX MX8210074U patent/MX7033E/es unknown
- 1982-05-13 CA CA000402887A patent/CA1187411A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE3272987D1 (en) | 1986-10-09 |
JPS57193418A (en) | 1982-11-27 |
DE3119157A1 (de) | 1982-12-09 |
AU547139B2 (en) | 1985-10-10 |
ATE21824T1 (de) | 1986-09-15 |
JPH0366292B2 (es) | 1991-10-16 |
US4442213A (en) | 1984-04-10 |
ES511982A0 (es) | 1983-02-01 |
EP0065256B1 (de) | 1986-09-03 |
NZ200589A (en) | 1985-04-30 |
EP0065256A3 (en) | 1984-01-18 |
IL65752A (en) | 1985-05-31 |
AU8366182A (en) | 1982-11-18 |
CA1187411A (en) | 1985-05-21 |
MX7033E (es) | 1987-03-03 |
IL65752A0 (en) | 1982-08-31 |
EP0065256A2 (de) | 1982-11-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20010402 |