ES8302664A1 - Un procedimiento para la preparacion de hidrocloruro del acido 4-(1-imidazolilmetil) cinamico monohidrato. - Google Patents
Un procedimiento para la preparacion de hidrocloruro del acido 4-(1-imidazolilmetil) cinamico monohidrato.Info
- Publication number
- ES8302664A1 ES8302664A1 ES509459A ES509459A ES8302664A1 ES 8302664 A1 ES8302664 A1 ES 8302664A1 ES 509459 A ES509459 A ES 509459A ES 509459 A ES509459 A ES 509459A ES 8302664 A1 ES8302664 A1 ES 8302664A1
- Authority
- ES
- Spain
- Prior art keywords
- imidazolylmethyl
- cinnamic acid
- acid hydrochloride
- hydrochloride monohydrate
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BVGINDBNCSPHPC-UHFFFAOYSA-N 3-[4-(1h-imidazol-2-ylmethyl)phenyl]prop-2-enoic acid;hydrate;hydrochloride Chemical compound O.Cl.C1=CC(C=CC(=O)O)=CC=C1CC1=NC=CN1 BVGINDBNCSPHPC-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 206010008190 Cerebrovascular accident Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 108010069102 Thromboxane-A synthase Proteins 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002460 imidazoles Chemical class 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000001589 microsome Anatomy 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56018488A JPS57131769A (en) | 1981-02-10 | 1981-02-10 | 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate, its preparation and drug containing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES509459A0 ES509459A0 (es) | 1983-01-16 |
| ES8302664A1 true ES8302664A1 (es) | 1983-01-16 |
Family
ID=11973016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509459A Expired ES8302664A1 (es) | 1981-02-10 | 1982-02-09 | Un procedimiento para la preparacion de hidrocloruro del acido 4-(1-imidazolilmetil) cinamico monohidrato. |
Country Status (14)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5855466A (ja) * | 1981-09-28 | 1983-04-01 | Kissei Pharmaceut Co Ltd | 新規な１，３−二置換イミダゾ−ル誘導体及びその製造方法 |
| TW208013B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1990-03-01 | 1993-06-21 | Daiichi Co Ltd | |
| US5215973A (en) * | 1991-03-07 | 1993-06-01 | Magis Farmaceutici S.P.A. | Optically active and racemic hydrated diacetylesters of α-glycero-phosphoryl-choline |
| CN114436964A (zh) * | 2020-10-16 | 2022-05-06 | 赤峰经方医药技术开发有限责任公司 | 一种奥扎格雷的连续制备方法 |
| US20240336638A1 (en) * | 2021-07-01 | 2024-10-10 | Guoqin ZHUGE | Imidazole compound, and intermediate and application thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55313A (en) * | 1978-06-13 | 1980-01-05 | Kissei Pharmaceut Co Ltd | Imidazole derivative |
-
1981
- 1981-02-10 JP JP56018488A patent/JPS57131769A/ja active Granted
-
1982
- 1982-02-02 ZA ZA82639A patent/ZA82639B/xx unknown
- 1982-02-03 AU AU80154/82A patent/AU546907B2/en not_active Ceased
- 1982-02-05 GR GR67226A patent/GR75408B/el unknown
- 1982-02-05 FI FI820379A patent/FI77028C/fi not_active IP Right Cessation
- 1982-02-08 CA CA000395781A patent/CA1173839A/en not_active Expired
- 1982-02-09 DK DK054982A patent/DK155736C/da not_active IP Right Cessation
- 1982-02-09 DE DE8282300619T patent/DE3261987D1/de not_active Expired
- 1982-02-09 IE IE289/82A patent/IE52519B1/en not_active IP Right Cessation
- 1982-02-09 EP EP82300619A patent/EP0058079B1/en not_active Expired
- 1982-02-09 ES ES509459A patent/ES8302664A1/es not_active Expired
- 1982-02-09 YU YU274/82A patent/YU42757B/xx unknown
- 1982-02-10 US US06/347,616 patent/US4607046A/en not_active Expired - Lifetime
- 1982-02-10 KR KR8200564A patent/KR880001865B1/ko not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI77028C (fi) | 1989-01-10 |
| KR830009043A (ko) | 1983-12-17 |
| JPS57131769A (en) | 1982-08-14 |
| EP0058079B1 (en) | 1985-01-23 |
| JPH0234941B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-08-07 |
| DK54982A (da) | 1982-08-11 |
| YU27482A (en) | 1985-03-20 |
| AU546907B2 (en) | 1985-09-26 |
| ZA82639B (en) | 1983-01-26 |
| YU42757B (en) | 1988-12-31 |
| ES509459A0 (es) | 1983-01-16 |
| KR880001865B1 (ko) | 1988-09-23 |
| DK155736B (da) | 1989-05-08 |
| IE52519B1 (en) | 1987-11-25 |
| EP0058079A2 (en) | 1982-08-18 |
| GR75408B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-07-13 |
| EP0058079A3 (en) | 1982-09-08 |
| CA1173839A (en) | 1984-09-04 |
| FI820379L (fi) | 1982-08-11 |
| FI77028B (fi) | 1988-09-30 |
| US4607046A (en) | 1986-08-19 |
| DK155736C (da) | 1989-09-25 |
| AU8015482A (en) | 1982-08-19 |
| DE3261987D1 (en) | 1985-03-07 |
| IE820289L (en) | 1982-08-10 |
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